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Record W4409567989 · doi:10.1111/jsr.70060

Prevalence of Altered Craniofacial Morphology in Children With <scp>OSA</scp>

2025· article· en· W4409567989 on OpenAlexafffundabout
Nelly Huynh, Jingjing Zhang, Benjamin T. Pliska, Reshma Amin, Indra Narang, Neil K. Chadha, Marie‐Claude Cholette, Val Kirk, Andrée Montpetit, Kevin Vézina, Sheila V. Jacob, Sophie Laberge, Mona M. Hamoda, Fernanda R. Almeida

Bibliographic record

VenueJournal of Sleep Research · 2025
Typearticle
Languageen
FieldMedicine
TopicObstructive Sleep Apnea Research
Canadian institutionsAlberta Children's HospitalBC Children's HospitalHospital for Sick ChildrenUniversity of British ColumbiaUniversité de MontréalCentre Hospitalier Universitaire Sainte-Justine
FundersCanadian Institutes of Health Research
KeywordsCraniofacialMedicinePolysomnographySleep BruxismCraniofacial abnormalityMalocclusionDentistryPediatricsInternal medicineApneaElectromyographyPhysical medicine and rehabilitation

Abstract

fetched live from OpenAlex

Snoring and obstructive sleep apnoea (OSA) affect a significant percentage of children. Recent studies have suggested that altered craniofacial morphology may contribute to the multifactorial pathophysiology of OSA. This study aims to determine the prevalence of craniofacial abnormalities and malocclusion in children referred for polysomnography due to OSA suspicion. This is a multicentre prevalence study completed across four Canadian sites. Otherwise, healthy children (≥ 4 years old) who were seen at the sleep clinic were recruited. Upon arrival for their hospital-based overnight sleep recording, a clinical orthodontic assessment and a series of paediatric sleep questionnaires were completed for each participant. Data from 315 children (age 9.37 ± 3.70) revealed significant risk factors associated with the presence of OSA, including male sex, presence of snoring, endomorph body type, and hypertrophic tonsils. The intra-oral and facial morphologic characteristics were not significantly different between children with (AHI 9.51 ± 10.94) and without (AHI 0.84 ± 0.50) PSG-verified OSA. Factors such as maxillary constriction/posterior crossbite and a retrognathic mandible showed similar (p > 0.05) prevalence between groups. Hierarchical regression analysis showed no statistically significant facial and dental variables in predicting AHI. In conclusion, a multidisciplinary approach involving dental professionals with expertise in growth and development is crucial for the assessment of possible craniofacial abnormalities in children with OSA. Craniofacial morphology may play a limited role in the pathophysiology of OSA in most children, as no differences in the prevalence of these variables in children with and without OSA were found in this large, multicentre study.

Fetched live from OpenAlex and de-inverted. Abstracts are not stored in this database: the inverted indexes are 8.6 GB of the frame’s 9.3 GB of text, and the host has 13 GB free.

How this classification was reachedexpand

Full frame distilled prediction

Teacher imitation

Not calibrated prevalence, not ground truth. Human validation pending. Learned from the 10,348 direct Codex labels and 10,348 direct Gemma labels. Candidate is the union of thresholded teacher heads; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels or direct frontier model labels.

metaresearch head score (Codex)0.003
metaresearch head score (Gemma)0.003
Version: codex-gemma-dda1882f352aValidation status: machine_predicted_unvalidated
Candidate categoriesnone
Consensus categoriesnone
DomainCandidate signal: none · Consensus signal: none
Study designCandidate signal: Observational · Consensus signal: Observational
GenreCandidate signal: Empirical · Consensus signal: Empirical
Teacher disagreement score0.018
Threshold uncertainty score0.845

Codex and Gemma teacher scores by category

CategoryCodexGemma
Metaresearch0.0030.003
Meta-epidemiology (narrow)0.0000.000
Meta-epidemiology (broad)0.0010.000
Bibliometrics0.0020.002
Science and technology studies0.0000.001
Scholarly communication0.0000.000
Open science0.0010.000
Research integrity0.0000.002
Insufficient payload (model declined to judge)0.0000.000

Machine scores (provisional)

The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.

Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.

Opus teacher head0.030
GPT teacher head0.365
Teacher spread0.335 · how far apart the two teachers sit on this one work
Validation statusscore_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from it

Classification

machine, unvalidated

Machine predicted; a candidate call from one teacher head, not a consensus.

The models applied no category: nothing in the taxonomy fit this work.
Study designObservational
Domainnot available
GenreEmpirical

How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".

Quick stats

Citations5
Published2025
Admission routes3
Has abstractyes

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