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Record W4409671966 · doi:10.1016/j.inpm.2025.100586

Lumbar facet joint denervation targeting the medial branch in the sub-mammillary fossa: An anatomical optimization study

2025· article· en· W4409671966 on OpenAlexaff
John Tran, Aaron Conger, Keaton Lightfoot, Zachary L. McCormick, Eldon Loh

Bibliographic record

VenueInterventional Pain Medicine · 2025
Typearticle
Languageen
FieldMedicine
TopicSpine and Intervertebral Disc Pathology
Canadian institutionsParkwood InstituteUniversity of TorontoWestern University
FundersInternational Pain and Spine Intervention Society
KeywordsMammillary bodyFacet (psychology)Facet jointMedicineAnatomyLumbarDenervationRadiologyPsychologyThalamus

Abstract

fetched live from OpenAlex

Introduction: Recent anatomical studies have identified the sub-mammillary fossa as a potential target site to extend the length and more reliably capture the medial branch during lumbar facet joint denervation. Although a clinical case series was published describing positive outcomes targeting the sub-mammillary fossa, the ideal location for radiofrequency cannula placement has not been assessed. Further anatomical investigation of this novel technique is warranted to refine fluoroscopic landmarks for optimal placement. Methods: Twelve cannulae were placed under fluoroscopic guidance targeting the L3, L4, & L5 medial branches in 2 embalmed cadaveric specimens. Dissection, digitization, and high-fidelity 3D modelling methodology was used to identify fluoroscopic landmarks. Lesion simulation was performed on 3D models to analyze nerve capture. Results: In 5 of 12 placements (41.7 %), the medial branch capture rate was classified as "complete," as the simulated lesion overlapped with the medial branch trunk or all of its distal branches. In 4 of 12 placements (33.3 %), the nerve capture rate was "partial" with at least one distal branch found beyond the boundary of the simulated lesion. In the remaining 3 placements (25.0 %), the capture rate was classified as "none," as the medial branch trunk and all distal branches transited beyond the simulated lesion boundary. Refined fluoroscopic landmarks proposed were the lateral boundary of mammillary process (AP view); the mamillo-accessory notch/inferior boundary of facet joint line (oblique view); and the inferior aspect of the mammillary process (lateral view). Conclusions: This anatomy optimization study used dissection, imaging correlation, and high-fidelity modelling to assess cannula placement for capture of the medial branch at the sub-mammillary fossa for lumbar facet joint denervation. Based on the present analysis, refined fluoroscopic landmarks were proposed for further investigation.

Fetched live from OpenAlex and de-inverted. Abstracts are not stored in this database: the inverted indexes are 8.6 GB of the frame’s 9.3 GB of text, and the host has 13 GB free.

How this classification was reachedexpand

Full frame distilled prediction

Teacher imitation

Not calibrated prevalence, not ground truth. Human validation pending. Learned from the 10,348 direct Codex labels and 10,348 direct Gemma labels. Candidate is the union of thresholded teacher heads; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels or direct frontier model labels.

metaresearch head score (Codex)0.006
metaresearch head score (Gemma)0.002
Version: codex-gemma-dda1882f352aValidation status: machine_predicted_unvalidated
Candidate categoriesnone
Consensus categoriesnone
DomainCandidate signal: none · Consensus signal: none
Study designCandidate signal: Observational · Consensus signal: Observational
GenreCandidate signal: Empirical · Consensus signal: Empirical
Teacher disagreement score0.448
Threshold uncertainty score0.473

Codex and Gemma teacher scores by category

CategoryCodexGemma
Metaresearch0.0060.002
Meta-epidemiology (narrow)0.0000.000
Meta-epidemiology (broad)0.0000.000
Bibliometrics0.0000.001
Science and technology studies0.0000.000
Scholarly communication0.0000.000
Open science0.0000.000
Research integrity0.0000.000
Insufficient payload (model declined to judge)0.0000.000

Machine scores (provisional)

The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.

Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.

Opus teacher head0.033
GPT teacher head0.338
Teacher spread0.305 · how far apart the two teachers sit on this one work
Validation statusscore_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from it

Classification

machine, unvalidated

Machine predicted; a candidate call from one teacher head, not a consensus.

The models applied no category: nothing in the taxonomy fit this work.
Study designObservational
Domainnot available
GenreEmpirical

How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".

Quick stats

Citations1
Published2025
Admission routes1
Has abstractyes

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