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Record W4409710238 · doi:10.3389/fped.2025.1565897

Long-term health outcomes of preterm birth: a narrative review

2025· review· en· W4409710238 on OpenAlexafffund
Faith Gette, Sumera Aziz Ali, Matthew Ho, Lindsay L. Richter, Edmond S. Chan, Connie Yang, Emily Kieran, Cherry Mammen, Ashley Roberts, Kristopher T. Kang, Jonathan Wong, Shahrad R. Rassekh, Michael Castaldo, Kevin C. Harris, James A. Lee, Carol Lam, Natalie Chan, Sarka Lisonkova, Joseph Ting

Bibliographic record

VenueFrontiers in Pediatrics · 2025
Typereview
Languageen
FieldMedicine
TopicNeonatal Respiratory Health Research
Canadian institutionsUniversity of TorontoUniversity of British ColumbiaUniversity of Alberta
FundersCanadian Institutes of Health ResearchAlberta InnovatesUniversity of Alberta
KeywordsMedicinePsychological interventionIntensive care medicinePediatricsPopulationIncidence (geometry)Health careNarrative reviewPsychiatryEnvironmental health

Abstract

fetched live from OpenAlex

Despite a significant reduction in neonatal mortality due to advances in neonatal care, preterm birth (PTB) continues to pose a challenge due to the escalating incidence of long-term complications, which refer to health issues that persist or emerge beyond the immediate neonatal period. The impact of PTB, particularly in extremely preterm infants born before 28 weeks of gestational age, is not confined to the early years but extends across the lifespan, influencing physical, cognitive, and social development, as well as long-term health outcomes. These complications, which often persist from childhood into adulthood, span multiple systems and create a broad spectrum of health concerns. This comprehensive narrative review of literature delves into the breadth of well-characterized long-term complications associated with PTB, including neurodevelopmental, respiratory, cardiovascular, renal, gastrointestinal, and endocrine system disorders. By providing health care providers with a holistic understanding of the potential complications following PTB, this review aims to summarize the current literature and underscore the value of long-term monitoring strategies and proactive evaluations of this population. Our objective is to foster a clinical approach that anticipates these complications, enabling early interventions and better management of these at-risk infants.

Fetched live from OpenAlex and de-inverted. Abstracts are not stored in this database: the inverted indexes are 8.6 GB of the frame’s 9.3 GB of text, and the host has 13 GB free.

How this classification was reachedexpand

Full frame machine prediction

Teacher imitation

Not calibrated prevalence, not ground truth. Human validation pending. The Gemma side is a direct model label for every work in the frame, read from the title-only record. The Codex side is a classifier learned from the 10,348 direct Codex labels and calibrated to design-weighted sample rates; fields without enough sample support carry no Codex call. Candidate is the union of the two sides; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels.

metaresearch head score (Codex)0.001
metaresearch head score (Gemma)0.006
Version: metacan-v3-hybrid-931329e0061cValidation status: machine_predicted_unvalidated
Candidate categoriesnone
Consensus categoriesnone
DomainCandidate signal: none · Consensus signal: none
Study designCandidate signal: Not applicable · Consensus signal: none
GenreCandidate signal: Review · Consensus signal: Review
Teacher disagreement score0.004
Threshold uncertainty score0.013

Distilled classifier scores by category (both heads)

CategoryCodexGemma
Metaresearch0.0010.006
Meta-epidemiology (narrow)0.0010.000
Meta-epidemiology (broad)0.0010.002
Bibliometrics0.0040.004
Science and technology studies0.0000.000
Scholarly communication0.0010.001
Open science0.0010.001
Research integrity0.0010.001
Insufficient payload (model declined to judge)0.0040.000

Machine scores (provisional)

The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.

Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.

Opus teacher head0.063
GPT teacher head0.447
Teacher spread0.384 · how far apart the two teachers sit on this one work
Validation statusscore_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from it

Classification

machine, unvalidated

Machine predicted; a candidate call from one source (direct Gemma or distilled Codex), not a consensus.

The models applied no category: nothing in the taxonomy fit this work.
Study designNot applicable
Domainnot available
GenreReview

How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".

Quick stats

Citations23
Published2025
Admission routes2
Has abstractyes

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