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Record W4409717891 · doi:10.1021/acs.est.4c11276

Unintended Consequences of Aquatic Enrichment in Experimental Biology

2025· review· en· W4409717891 on OpenAlexafffund
Tamzin A. Blewett, Kerri Lynn Ackerly, Josefin Sundin, Thomas D. Clark, Lauren E. Rowsey, Robert Griffin, Moa Metz, Luis Kuchenmüller, Robine H. J. Leeuwis, Marie Levet, Sidney Martin, Ben Speers‐Roesch, Fredrik Jutfelt, Shira Joudan

Bibliographic record

VenueEnvironmental Science & Technology · 2025
Typereview
Languageen
FieldVeterinary
TopicAnimal testing and alternatives
Canadian institutionsUniversité de MontréalUniversity of New BrunswickUniversity of Alberta
FundersNatural Sciences and Engineering Research Council of CanadaAustralian Government
KeywordsUnintended consequencesEnvironmental chemistryBiologyEnvironmental scienceBiochemical engineeringChemistryEngineeringPolitical science

Abstract

fetched live from OpenAlex

Enrichment in aquatic animal studies is important for promoting welfare and maintaining animal health and can be categorized by physical, sensory, social, occupational, and dietary enrichment. However, the risk of potential chemical leaching associated with physical enrichment items has been largely overlooked (i.e., artificial plants or shelter). Most enrichment items lack information on their chemical composition and have not undergone testing for plastic or metal leachates that can alter water chemistry and impair animal physiology. In fish and invertebrate research, these leachates have the potential to modify the health of aquatic animals or their reproductive processes. Moreover, in toxicology research, altered chemical exposure concentrations and interactive effects with leachates could invalidate toxicity assays and lead to misleading results. We identify key contaminants associated with common enrichment items and highlight the substantial lack of empirical research focusing on the confounding factors associated with aquatic enrichment. We explore the mechanisms through which relevant leachates can complicate experimental outcomes, detailing the pathways by which these substances may interact with both the experimental environment and the animals themselves. We conclude that there is widespread potential for serious complications to research outcomes and chronic toxicity from enrichment materials. Therefore, we advocate for the establishment of standardized regulations and a global certification system for aquatic enrichment items to ensure the validity of studies and to safeguard animal welfare. We encourage researchers to critically consider the implications of leaching from aquatic enrichment when designing experimental systems.

Fetched live from OpenAlex and de-inverted. Abstracts are not stored in this database: the inverted indexes are 8.6 GB of the frame’s 9.3 GB of text, and the host has 13 GB free.

How this classification was reachedexpand

Full frame machine prediction

Teacher imitation

Not calibrated prevalence, not ground truth. Human validation pending. The Gemma side is a direct model label for every work in the frame, read from the title-only record. The Codex side is a classifier learned from the 10,348 direct Codex labels and calibrated to design-weighted sample rates; fields without enough sample support carry no Codex call. Candidate is the union of the two sides; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels.

metaresearch head score (Codex)0.007
metaresearch head score (Gemma)0.008
Version: metacan-v3-hybrid-931329e0061cValidation status: machine_predicted_unvalidated
Candidate categoriesnone
Consensus categoriesnone
DomainCandidate signal: none · Consensus signal: none
Study designCandidate signal: Not applicable · Consensus signal: none
GenreCandidate signal: Review · Consensus signal: Review
Teacher disagreement score0.007
Threshold uncertainty score0.036

Distilled classifier scores by category (both heads)

CategoryCodexGemma
Metaresearch0.0070.008
Meta-epidemiology (narrow)0.0010.000
Meta-epidemiology (broad)0.0010.001
Bibliometrics0.0010.001
Science and technology studies0.0000.003
Scholarly communication0.0010.002
Open science0.0020.001
Research integrity0.0020.002
Insufficient payload (model declined to judge)0.0040.001

Machine scores (provisional)

The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.

Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.

Opus teacher head0.107
GPT teacher head0.419
Teacher spread0.313 · how far apart the two teachers sit on this one work
Validation statusscore_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from it

Classification

machine, unvalidated

Machine predicted; a candidate call from one source (direct Gemma or distilled Codex), not a consensus.

The models applied no category: nothing in the taxonomy fit this work.
Study designNot applicable
Domainnot available
GenreReview

How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".

Quick stats

Citations3
Published2025
Admission routes2
Has abstractyes

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