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Record W4409732777 · doi:10.11124/jbies-24-00556

Systems for assessing the certainty or confidence of evidence in health care: a scoping review protocol

2025· review· en· W4409732777 on OpenAlexaff
Lucylynn Lizarondo, Heather Loveday, Susan Salmond, Kay Cooper, Christina Godfrey, Danielle Pollock, Kendra L. Rieger, Amanda Vandyk, Chandrashekar Janakiram, Nisha Kurian, Jacopo Fiorini, Cindy Stern

Bibliographic record

VenueJBI Evidence Synthesis · 2025
Typereview
Languageen
FieldDecision Sciences
TopicMeta-analysis and systematic reviews
Canadian institutionsUniversity of OttawaTrinity Western UniversityWestern UniversityQueen's University
Fundersnot available
KeywordsCertaintyCritical appraisalManagement scienceSystematic reviewHealth careProtocol (science)Computer scienceData extractionGrey literatureMEDLINEMedicineEngineeringAlternative medicinePolitical science

Abstract

fetched live from OpenAlex

OBJECTIVE: This scoping review aims to identify existing systems, frameworks, or approaches for assessing certainty or confidence in quantitative, qualitative, and mixed methods evidence, providing a foundation for developing a unified framework tailored to mixed methods reviews. INTRODUCTION: Assessing the certainty or confidence in evidence is essential for developing health care recommendations, yet current frameworks are often limited to either quantitative or qualitative paradigms. With the rise of mixed methods research, which integrates quantitative and qualitative evidence to address complex health care questions, there is a growing need for systems capable of evaluating certainty across these diverse evidence types. ELIGIBILITY CRITERIA: This scoping review will include systems, frameworks, or approaches explicitly developed to assess the certainty or confidence in evidence from quantitative, qualitative, or mixed methods studies. Eligible papers must describe the methodology, criteria, or principles of these systems or discuss their development, validation, or theoretical foundations. Systems focused solely on critical appraisal or quality assessment of individual studies will be excluded unless they integrate these assessments into a broader framework for assessing certainty in a body of evidence. METHODS: This review will be conducted in accordance with the JBI methodology for scoping reviews and reported using the Preferred Reporting Items for Systematic Reviews and Meta-Analyses extension for scoping reviews (PRISMA-ScR) guidelines. A comprehensive 3-step search strategy will identify published, unpublished, and gray literature from databases, organizational websites, and reference lists. Data will be extracted using a piloted extraction table and presented in tables, figures, and a narrative summary to map existing systems, frameworks, or approaches for assessing certainty or confidence in evidence. REVIEW REGISTRATION: OSF https://osf.io/36n78/.

Fetched live from OpenAlex and de-inverted. Abstracts are not stored in this database: the inverted indexes are 8.6 GB of the frame’s 9.3 GB of text, and the host has 13 GB free.

How this classification was reachedexpand

Full frame machine prediction

Teacher imitation

Not calibrated prevalence, not ground truth. Human validation pending. The Gemma side is a direct model label for every work in the frame, read from the title-only record. The Codex side is a classifier learned from the 10,348 direct Codex labels and calibrated to design-weighted sample rates; fields without enough sample support carry no Codex call. Candidate is the union of the two sides; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels.

metaresearch head score (Codex)0.290
metaresearch head score (Gemma)0.311
Version: metacan-v3-hybrid-931329e0061cValidation status: machine_predicted_unvalidated
Candidate categoriesMetaresearch
Consensus categoriesMetaresearch
DomainCandidate signal: Methods · Consensus signal: none
Study designCandidate signal: Not applicable · Consensus signal: none
GenreCandidate signal: Protocol · Consensus signal: Protocol
Teacher disagreement score0.710
Threshold uncertainty score0.876

Distilled classifier scores by category (both heads)

CategoryCodexGemma
Metaresearch0.2900.311
Meta-epidemiology (narrow)0.0050.007
Meta-epidemiology (broad)0.0100.016
Bibliometrics0.0300.027
Science and technology studies0.0080.009
Scholarly communication0.0140.013
Open science0.0080.016
Research integrity0.0120.012
Insufficient payload (model declined to judge)0.0830.029

Machine scores (provisional)

The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.

Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.

Opus teacher head0.789
GPT teacher head0.657
Teacher spread0.132 · how far apart the two teachers sit on this one work
Validation statusscore_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from it

Classification

machine, unvalidated

Machine predicted; the direct Gemma label and the distilled Codex classifier agree on what is shown here.

Study designNot applicable
DomainMethods
GenreProtocol

How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".

Quick stats

Citations1
Published2025
Admission routes1
Has abstractyes

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