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Record W4409737869 · doi:10.1016/j.watres.2025.123714

Legislative and precautionary approaches to managing pharmaceutical contaminants in Canadian freshwaters

2025· review· en· W4409737869 on OpenAlexafffundabout
Oluwatosin Joseph Aladekoyi, Patricia Hania, Rania Hamza, Kimberley Gilbride

Bibliographic record

VenueWater Research · 2025
Typereview
Languageen
FieldEnvironmental Science
TopicPharmaceutical and Antibiotic Environmental Impacts
Canadian institutionsToronto ZooUniversity of Toronto
FundersSocial Sciences and Humanities Research Council
KeywordsLegislaturePrecautionary principleEnvironmental planningWater contaminationEnvironmental scienceContaminationEnvironmental protectionBusinessPolitical scienceLawEcologyBiology

Abstract

fetched live from OpenAlex

• Pharmaceuticals pose serious risks to Canada’s freshwater ecosystems. • Outdated wastewater treatment plants are unable to effectively remove harmful pharmaceutical residues. • Europe’s innovative strategies provide actionable solutions to safeguard Canada’s water resources. • The recent CEPA amendments may offer solutions to mitigating pharmaceutical pollution in Canadian freshwater. Pharmaceuticals are increasingly recognized as contaminants of emerging concern in aquatic environments due to their potential ecological impacts. In Canada, pharmaceutical pollution remains an under-regulated issue within federal chemical management policy. This study critically examines the extent to which Canada’s Chemicals Management Plan (CMP), under the Canadian Environmental Protection Act (CEPA), addresses the risks posed by pharmaceuticals in freshwater systems. Through a review of recent legislation and scientific information, the study identifies regulatory gaps, including limitations in current wastewater treatment practices and ecological risk assessments. The CMP sets out guidelines for assessing and managing chemicals under CEPA to minimize the risks posed by toxic substances. Despite scientific evidence of toxicity to aquatic ecosystems, relatively few pharmaceuticals have been assessed under the CMP. This article explores how Canada’s multi-level governments can strengthen pharmaceutical pollution governance, particularly in light of the 2023 legislative amendments to CEPA. Drawing on comparative insights from the European Union, the study emphasizes the need to integrate expanded pharmaceutical screening criteria, enhanced monitoring, and revised persistence and bioaccumulation thresholds into the CMP framework. These improvements would enable Canada to adopt a more adaptive and precautionary approach to managing pharmaceutical pollution in aquatic ecosystems while contributing to global efforts that advance sustainable water management practices.

Fetched live from OpenAlex and de-inverted. Abstracts are not stored in this database: the inverted indexes are 8.6 GB of the frame’s 9.3 GB of text, and the host has 13 GB free.

How this classification was reachedexpand

Full frame machine prediction

Teacher imitation

Not calibrated prevalence, not ground truth. Human validation pending. The Gemma side is a direct model label for every work in the frame, read from the title-only record. The Codex side is a classifier learned from the 10,348 direct Codex labels and calibrated to design-weighted sample rates; fields without enough sample support carry no Codex call. Candidate is the union of the two sides; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels.

metaresearch head score (Codex)0.018
metaresearch head score (Gemma)0.023
Version: metacan-v3-hybrid-931329e0061cValidation status: machine_predicted_unvalidated
Candidate categoriesnone
Consensus categoriesnone
DomainCandidate signal: none · Consensus signal: none
Study designCandidate signal: Not applicable · Consensus signal: none
GenreCandidate signal: Review · Consensus signal: none
Teacher disagreement score0.172
Threshold uncertainty score0.960

Distilled classifier scores by category (both heads)

CategoryCodexGemma
Metaresearch0.0180.023
Meta-epidemiology (narrow)0.0010.001
Meta-epidemiology (broad)0.0010.001
Bibliometrics0.0060.005
Science and technology studies0.0150.010
Scholarly communication0.0090.003
Open science0.0060.005
Research integrity0.0050.006
Insufficient payload (model declined to judge)0.0030.000

Machine scores (provisional)

The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.

Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.

Opus teacher head0.330
GPT teacher head0.431
Teacher spread0.101 · how far apart the two teachers sit on this one work
Validation statusscore_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from it

Classification

machine, unvalidated

Machine predicted; a candidate call from one source (direct Gemma or distilled Codex), not a consensus.

The models applied no category: nothing in the taxonomy fit this work.
Study designNot applicable
Domainnot available
GenreReview

How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".

Quick stats

Citations4
Published2025
Admission routes3
Has abstractyes

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