Is robotic-arm-assisted total knee arthroplasty less traumatic? A meta-analysis
Bibliographic record
Abstract
Objective was to identify inflammatory responses that predict postoperative total knee arthroplasty (TKA) outcome. The robotic TKA has resulted decreased tissue trauma. This review aims to determine the level 1 evidence of inflammatory responses following robotic and conventional jig-based TKA as inflammatory markers provide an objective method for assessing the invasiveness of the surgery. A systematic search according to the guidelines for preferred reporting items for systematic reviews and meta-analysis (PRISMA) of the existing literature was performed on the electronic databases PubMed, Scopus and Ovid until the 1st of June 2023. Inclusion criteria were randomized controlled trials (RCTs), written in the English language and published in the last ten years, focusing on studies that evaluated the influence of inflammatory markers (O) on robotic TKA (I) and conventional jig based (C) TKA in end-stage knee osteoarthritis patients (P) were included in the study. The inverse variance method analyzed continuous outcomes as standard mean difference (SMD), random effect model and 95% confidence intervals (CI). In total, among the 557 articles, four studies were included. One hundred sixty-five patients were included, and various inflammatory markers and patient-reported outcome measures were analysed. This meta-analysis showed that R-TKA showed a decreased inflammatory response compared to C-TKA [interleukin (IL)-6 (Std. mean diff. {IV, random, 95 CI}=-1.22 {-1.78, -0.66}, C reactive protein (CRP) (-1.07 {-2.01, -0.13}, erythrocyte sedimentation rate (ESR)=-0.65 {-1.17,-0.12} with a significant p<0.05] with no significant changes in terms of patient-reported outcome measures Western Ontario and McMaster universities osteoarthritis index (WOMAC)=-0.25 {-0.59,0.09}, knee society score (KSS)=0.18 {-0.34, 0.70}, and functional outcome range of motion (ROM)=-0.22 {-0.62, 0.17} with a p>0.05. Robotic-arm-assisted TKA has decreased early postoperative inflammatory response. High powered studies assessing the predictive value of metabolic and inflammatory factors pre and post-surgery and the already evidenced risk factors with follow-up greater than one year after TKA are warranted.
Fetched live from OpenAlex and de-inverted. Abstracts are not stored in this database: the inverted indexes are 8.6 GB of the frame’s 9.3 GB of text, and the host has 13 GB free.
How this classification was reachedexpand
Full frame distilled prediction
Teacher imitationNot calibrated prevalence, not ground truth. Human validation pending. Learned from the 10,348 direct Codex labels and 10,348 direct Gemma labels. Candidate is the union of thresholded teacher heads; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels or direct frontier model labels.
Codex and Gemma teacher scores by category
| Category | Codex | Gemma |
|---|---|---|
| Metaresearch | 0.004 | 0.002 |
| Meta-epidemiology (narrow) | 0.000 | 0.000 |
| Meta-epidemiology (broad) | 0.001 | 0.002 |
| Bibliometrics | 0.004 | 0.003 |
| Science and technology studies | 0.000 | 0.000 |
| Scholarly communication | 0.000 | 0.000 |
| Open science | 0.000 | 0.000 |
| Research integrity | 0.000 | 0.002 |
| Insufficient payload (model declined to judge) | 0.001 | 0.000 |
Machine scores (provisional)
The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.
Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.
score_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from itClassification
machine, unvalidatedMachine predicted; a candidate call from one teacher head, not a consensus.
How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".