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Record W4409818715 · doi:10.1017/rsm.2025.20

Same, same, but different: A method to harmonise and deduplicate study records from WHO ICTRP and ClinicalTrials.gov prior to screening

2025· article· en· W4409818715 on OpenAlexaff
Zahra Premji, Chris Cooper

Bibliographic record

VenueResearch Synthesis Methods · 2025
Typearticle
Languageen
FieldHealth Professions
TopicMedical Coding and Health Information
Canadian institutionsUniversity of Victoria
Fundersnot available
KeywordsComputer scienceMedicineStatisticsMathematics

Abstract

fetched live from OpenAlex

Trials registry records represent a challenge in deduplication compared to deduplicating studies reported in journals and exported from bibliographic databases such as MEDLINE. We demonstrate why this is the case and propose a method to deduplicate registry records from the WHO International Clinical Trials Registry Platform (ICTRP) and ClinicalTrials.gov (CTG) specifically in the reference management tool EndNote (desktop version). We believe that our method is not only more efficient but that it will minimise the risk of registry records being incorrectly removed as duplicates in automated deduplication. The method has seven steps and is detailed in this tutorial as a step-by-step guide.

Fetched live from OpenAlex and de-inverted. Abstracts are not stored in this database: the inverted indexes are 8.6 GB of the frame’s 9.3 GB of text, and the host has 13 GB free.

How this classification was reachedexpand

Full frame machine prediction

Teacher imitation

Not calibrated prevalence, not ground truth. Human validation pending. The Gemma side is a direct model label for every work in the frame, read from the title-only record. The Codex side is a classifier learned from the 10,348 direct Codex labels and calibrated to design-weighted sample rates; fields without enough sample support carry no Codex call. Candidate is the union of the two sides; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels.

metaresearch head score (Codex)0.142
metaresearch head score (Gemma)0.457
Version: metacan-v3-hybrid-931329e0061cValidation status: machine_predicted_unvalidated
Candidate categoriesMetaresearch
Consensus categoriesnone
DomainCandidate signal: Methods · Consensus signal: none
Study designCandidate signal: Simulation or modeling · Consensus signal: none
GenreCandidate signal: Methods · Consensus signal: Methods
Teacher disagreement score0.858
Threshold uncertainty score0.752

Distilled classifier scores by category (both heads)

CategoryCodexGemma
Metaresearch0.1420.457
Meta-epidemiology (narrow)0.0020.003
Meta-epidemiology (broad)0.0020.003
Bibliometrics0.0220.017
Science and technology studies0.0030.002
Scholarly communication0.0080.010
Open science0.0040.008
Research integrity0.0030.004
Insufficient payload (model declined to judge)0.0300.014

Machine scores (provisional)

The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.

Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.

Opus teacher head0.656
GPT teacher head0.684
Teacher spread0.028 · how far apart the two teachers sit on this one work
Validation statusscore_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from it

Classification

machine, unvalidated

Machine predicted; a candidate call from one source (direct Gemma or distilled Codex), not a consensus.

Study designSimulation or modeling
DomainMethods
GenreMethods

How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".

Quick stats

Citations0
Published2025
Admission routes1
Has abstractyes

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