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Record W4409916942 · doi:10.1371/journal.pgph.0003606

Sepsis research in Canada: An environmental scan of sepsis investigators, research, and funding

2025· article· en· W4409916942 on OpenAlexaffabout
Muhadisa Ali, Saad Y. Salim, Fatima Sheikh, Alison Fox‐Robichaud

Bibliographic record

VenuePLOS Global Public Health · 2025
Typearticle
Languageen
FieldMedicine
TopicSepsis Diagnosis and Treatment
Canadian institutionsHamilton Health SciencesImpactMcMaster University
Fundersnot available
KeywordsSepsisScope (computer science)MedicineDescriptive statisticsFamily medicineInternal medicineStatistics

Abstract

fetched live from OpenAlex

Sepsis is the world's second leading cause of mortality. In 2017, the World Health Assembly declared sepsis a global priority and adopted a resolution prompting member states to improve the prevention, recognition, and management of sepsis. This cross-sectional study examines the sepsis research landscape in Canada, including demographics, scope, and funding. Using convenient sampling, sepsis researchers in Canada were asked to complete an online 20-question survey. We also scanned the CIHR funding database from 2012-2022 to quantify national research dollars spent on sepsis-related projects. Quantitative data was summarized using descriptive statistics, and textual descriptions of current sepsis research activities were analyzed thematically. With a response rate of 46% (69 of the 150), respondents were primarily men (n = 46/69, 67%), who identified as White/European (n = 49/69, 71%), and were professors or clinical professors (n = 36/69, 52%). The predominant areas of research focus were identification of sepsis (n = 21/55, 38%) and treatment/management (29/55, 53%) of sepsis, while sepsis prevention (n = 4/55, 7%) and sepsis education (n = 5/55, 9%) garnered less attention. Past 10 years of CIHR funding data revealed that only 0.7% ($85 million) of total funding ($11 billion) was towards sepsis research, of which only 2 were new-investigator awards. This study illustrates the need for improving the diversity of sepsis researchers in Canada; expanding the scope of research to address sepsis prevention, recovery, and education; and increasing overall funding to sepsis.

Fetched live from OpenAlex and de-inverted. Abstracts are not stored in this database: the inverted indexes are 8.6 GB of the frame’s 9.3 GB of text, and the host has 13 GB free.

How this classification was reachedexpand

Full frame distilled prediction

Teacher imitation

Not calibrated prevalence, not ground truth. Human validation pending. Learned from the 10,348 direct Codex labels and 10,348 direct Gemma labels. Candidate is the union of thresholded teacher heads; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels or direct frontier model labels.

metaresearch head score (Codex)0.002
metaresearch head score (Gemma)0.000
Version: codex-gemma-dda1882f352aValidation status: machine_predicted_unvalidated
Candidate categoriesnone
Consensus categoriesnone
DomainCandidate signal: none · Consensus signal: none
Study designCandidate signal: Observational · Consensus signal: Observational
GenreCandidate signal: Empirical · Consensus signal: Empirical
Teacher disagreement score0.107
Threshold uncertainty score0.994

Codex and Gemma teacher scores by category

CategoryCodexGemma
Metaresearch0.0020.000
Meta-epidemiology (narrow)0.0000.000
Meta-epidemiology (broad)0.0000.000
Bibliometrics0.0000.002
Science and technology studies0.0000.000
Scholarly communication0.0000.000
Open science0.0000.000
Research integrity0.0000.000
Insufficient payload (model declined to judge)0.0000.000

Machine scores (provisional)

The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.

Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.

Opus teacher head0.419
GPT teacher head0.466
Teacher spread0.046 · how far apart the two teachers sit on this one work
Validation statusscore_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from it

Classification

machine, unvalidated

Machine predicted; a candidate call from one teacher head, not a consensus.

The models applied no category: nothing in the taxonomy fit this work.
Study designObservational
Domainnot available
GenreEmpirical

How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".

Quick stats

Citations0
Published2025
Admission routes2
Has abstractyes

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