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Record W4409980549 · doi:10.51253/pafmj.v75i2.11240

Comparison of Corticosteroids Effectiveness via High Volume Nasal Irrigation versus Conventional Nasal Spray after Endoscopic Sinus Surgery in Nasal Polyposi

2025· article· en· W4409980549 on OpenAlexaff
Chaudhry Muhammad Bilal Akram, Abdul Hakim, Aftab Hussain, Muhammad Zubair Khan, Maryam Khan, Kamran Ashfaq Ahmed Butt

Bibliographic record

VenuePakistan Armed Forces Medical Journal · 2025
Typearticle
Languageen
FieldMedicine
TopicSinusitis and nasal conditions
Canadian institutionsBombardier (Canada)
Fundersnot available
KeywordsMedicineNasal sprayEndoscopic sinus surgerySurgeryNasal administrationChronic rhinosinusitisAnesthesiaPharmacology

Abstract

fetched live from OpenAlex

Objective: To compare the efficacy of two different methods of topical corticosteroid delivery techniques; conventional nasal spray versus high volume nasal irrigation with squeeze bottle, post-operatively in patients of nasal polyposis. Study Design: Quasi-experimental study. Place and Duration of Study: Department of Ear Nose Throat, Combined Military Hospital, Kohat Pakistan, from Sep 2021 to Aug 2022. Methodology: A total of 80 patients diagnosed with nasal polyposis were recruited for this study. Selected patients were divided into two equal groups. Pre-operatively all patients were carefully assessed with the help of Sino-nasal outcome test 22 (SNOT 22) and Lund Kennedy Endoscopy score for severity of symptoms. Post-operatively, Group-A received Betamethasone via high volume irrigation by squeeze bottle whereas Group-B received the Beclomethasone via conventional nasal spray. This treatment plan continued for 3 months. Post-operatively, SNOT 22 and Lund Kennedy Endoscopy score assessment was carried out at 3 months. Results: Both groups were comparable with respect to demographic data. In Group-A pre-op median and interquartile range for SNOT score was 68 and 10 respectively and it was reduced to 14 and 5 post-operatively, whereas in Group-B, it was 68 and 10; 27 and 5.5 pre and post-operatively. Post-operative difference was significant (p-value=0.001). Similarly, in Group-A, pre and post-operative median and interquartile range for LKE score 6 and 1 respectively and 2 and 0, whereas in Group-B it was 6.22 and 0.4 and 1.5 with statistically significant post-operative difference (p-value=0.001). Conclusion: High volume irrigation with squeeze bottle is more effective method of delivering....

Fetched live from OpenAlex and de-inverted. Abstracts are not stored in this database: the inverted indexes are 8.6 GB of the frame’s 9.3 GB of text, and the host has 13 GB free.

How this classification was reachedexpand

Full frame machine prediction

Teacher imitation

Not calibrated prevalence, not ground truth. Human validation pending. The Gemma side is a direct model label for every work in the frame, read from the title-only record. The Codex side is a classifier learned from the 10,348 direct Codex labels and calibrated to design-weighted sample rates; fields without enough sample support carry no Codex call. Candidate is the union of the two sides; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels.

metaresearch head score (Codex)0.001
metaresearch head score (Gemma)0.001
Version: metacan-v3-hybrid-931329e0061cValidation status: machine_predicted_unvalidated
Candidate categoriesnone
Consensus categoriesnone
DomainCandidate signal: none · Consensus signal: none
Study designCandidate signal: Observational · Consensus signal: none
GenreCandidate signal: Empirical · Consensus signal: Empirical
Teacher disagreement score0.001
Threshold uncertainty score0.004

Distilled classifier scores by category (both heads)

CategoryCodexGemma
Metaresearch0.0010.001
Meta-epidemiology (narrow)0.0000.000
Meta-epidemiology (broad)0.0010.000
Bibliometrics0.0000.000
Science and technology studies0.0000.000
Scholarly communication0.0000.000
Open science0.0000.000
Research integrity0.0000.000
Insufficient payload (model declined to judge)0.0010.000

Machine scores (provisional)

The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.

Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.

Opus teacher head0.017
GPT teacher head0.352
Teacher spread0.335 · how far apart the two teachers sit on this one work
Validation statusscore_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from it

Classification

machine, unvalidated

Machine predicted; a candidate call from one source (direct Gemma or distilled Codex), not a consensus.

The models applied no category: nothing in the taxonomy fit this work.
Study designObservational
Domainnot available
GenreEmpirical

How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".

Quick stats

Citations0
Published2025
Admission routes1
Has abstractyes

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