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Record W4410031308 · doi:10.1097/dad.0000000000002991

A Rare Presentation of Pancreatic Panniculitis-like Reaction After a Wasp Sting

2025· article· en· W4410031308 on OpenAlexaff
Sophia Luyten, Apoorva Mehta, Alejandro A. Gru, Sadia Salim

Bibliographic record

VenueAmerican Journal of Dermatopathology · 2025
Typearticle
Languageen
FieldMedicine
TopicFood Allergy and Anaphylaxis Research
Canadian institutionsNexen (Canada)
Fundersnot available
KeywordsPanniculitisStingMedicineDermatologyNecrosisPathologyErythema

Abstract

fetched live from OpenAlex

ABSTRACT: Localized skin necrosis after bee and wasp stings is an exceptionally rare phenomenon, with few reported cases documented in the literature. Hymenoptera stings, including those from wasps, bees, and stinging ants, are common worldwide and typically result in localized reactions such as pain, erythema, and swelling. Although systemic complications, including anaphylaxis and multiorgan damage, are well recognized, localized skin necrosis remains poorly understood. In this study, we present a rare case of localized dermal necrosis in a 75-year-old woman with no systemic involvement after a yellow jacket sting. Notably, histopathologic examination revealed a lobal panniculitis with fat saponification with calcium deposition and ghost adipocytes-findings strikingly similar to pancreatic panniculitis. No infectious organisms or retained arthropod parts were identified. Wasp venom components include enzymes, proteins, and amines that cause type I hypersensitivity reactions and cause direct toxin-mediated tissue damage, yet the direct mechanism behind cutaneous damage is not well understood. This case represents the first reported instance of a pancreatic panniculitis-like reaction after a wasp sting, and contributes to the limited literature on wasp venom-induced skin necrosis.

Fetched live from OpenAlex and de-inverted. Abstracts are not stored in this database: the inverted indexes are 8.6 GB of the frame’s 9.3 GB of text, and the host has 13 GB free.

How this classification was reachedexpand

Full frame distilled prediction

Teacher imitation

Not calibrated prevalence, not ground truth. Human validation pending. Learned from the 10,348 direct Codex labels and 10,348 direct Gemma labels. Candidate is the union of thresholded teacher heads; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels or direct frontier model labels.

metaresearch head score (Codex)0.000
metaresearch head score (Gemma)0.000
Version: codex-gemma-dda1882f352aValidation status: machine_predicted_unvalidated
Candidate categoriesnone
Consensus categoriesnone
DomainCandidate signal: none · Consensus signal: none
Study designCandidate signal: Observational · Consensus signal: Observational
GenreCandidate signal: Empirical · Consensus signal: Empirical
Teacher disagreement score0.215
Threshold uncertainty score0.291

Codex and Gemma teacher scores by category

CategoryCodexGemma
Metaresearch0.0000.000
Meta-epidemiology (narrow)0.0000.000
Meta-epidemiology (broad)0.0000.000
Bibliometrics0.0000.000
Science and technology studies0.0000.000
Scholarly communication0.0000.000
Open science0.0000.000
Research integrity0.0000.000
Insufficient payload (model declined to judge)0.0000.000

Machine scores (provisional)

The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.

Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.

Opus teacher head0.009
GPT teacher head0.304
Teacher spread0.295 · how far apart the two teachers sit on this one work
Validation statusscore_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from it

Classification

machine, unvalidated

Machine predicted; a candidate call from one teacher head, not a consensus.

The models applied no category: nothing in the taxonomy fit this work.
Study designObservational
Domainnot available
GenreEmpirical

How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".

Quick stats

Citations0
Published2025
Admission routes1
Has abstractyes

Explore more

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