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Record W4410075193 · doi:10.1101/2025.04.29.651003

Task-specificity of local load feedback depends on intersegmental information in an insect walking system

2025· preprint· en· W4410075193 on OpenAlexaff
Angelina Ruthe, Alkan Özyer, Turgay Akay, Ansgar Büschges

Bibliographic record

VenuebioRxiv (Cold Spring Harbor Laboratory) · 2025
Typepreprint
Languageen
FieldNeuroscience
TopicNeurobiology and Insect Physiology Research
Canadian institutionsDalhousie University
FundersDeutsche Forschungsgemeinschaft
KeywordsInsectTask (project management)Computer scienceControl theory (sociology)Human–computer interactionCommunicationBiological systemNeuroscienceBiologyPsychologyArtificial intelligenceEcologyEngineeringControl (management)Systems engineering

Abstract

fetched live from OpenAlex

Abstract Load proprioceptive feedback measured by campaniform sensilla (CS) substantially contributes to the generation of leg stepping during walking. In stick insects, the effect of load feedback on the antagonistic protractor and retractor motor neurons (MNs) reverses depending on the walking direction to support the functional stance MN pool in both stepping directions. However, this was shown in highly reduced preparations in which the stimulated leg did not perform actual stepping movements, but the effect was inferred from MN activity profiles. It is still largely unknown whether the load feedback similarly shows a direction dependent reversal in its effects on protractor and retractor activity during actual stepping of the stimulated leg. Here, we implemented load stimulation in a single-middle leg preparation and recorded protractor and retractor MN activity extracellularly during fictive forward and backward stepping. We show that CS stimulation during the stance phase prolonged stance (retractor) activity for the duration of the stimulation and induced stance (retractor) activity when applied during the swing phase in forward stepping. During backward stepping, when protractor and retractor switch phases, the same stimulation again prolonged stance (protractor) activity for the duration of the stimulation. However, it rarely induced stance (protractor) activity when applied during the swing phase. We provide evidence that this is due to the absence of signals about the stepping direction of the neighboring legs, thus highlighting the importance of intersegmental signals for task-specific processing of load proprioceptive feedback. New and Noteworthy Proprioceptive feedback needs to be processed in a task-dependent manner to serve its function, even when the leg kinematics change to generate different behaviors. We show for forward and backward stepping that load signals initiate and maintain the activity of the functional stance phase motor neuron pool and that intersegmental signals about stepping of the neighboring legs are relevant for the task-specific processing of load feedback.

Fetched live from OpenAlex and de-inverted. Abstracts are not stored in this database: the inverted indexes are 8.6 GB of the frame’s 9.3 GB of text, and the host has 13 GB free.

How this classification was reachedexpand

Full frame machine prediction

Teacher imitation

Not calibrated prevalence, not ground truth. Human validation pending. The Gemma side is a direct model label for every work in the frame, read from the title-only record. The Codex side is a classifier learned from the 10,348 direct Codex labels and calibrated to design-weighted sample rates; fields without enough sample support carry no Codex call. Candidate is the union of the two sides; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels.

metaresearch head score (Codex)0.000
metaresearch head score (Gemma)0.000
Version: metacan-v3-hybrid-931329e0061cValidation status: machine_predicted_unvalidated
Candidate categoriesnone
Consensus categoriesnone
DomainCandidate signal: none · Consensus signal: none
Study designCandidate signal: Bench or experimental · Consensus signal: Bench or experimental
GenreCandidate signal: Empirical · Consensus signal: Empirical
Teacher disagreement score0.001
Threshold uncertainty score0.003

Distilled classifier scores by category (both heads)

CategoryCodexGemma
Metaresearch0.0000.000
Meta-epidemiology (narrow)0.0000.000
Meta-epidemiology (broad)0.0000.000
Bibliometrics0.0000.000
Science and technology studies0.0000.000
Scholarly communication0.0000.000
Open science0.0000.000
Research integrity0.0000.000
Insufficient payload (model declined to judge)0.0010.000

Machine scores (provisional)

The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.

Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.

Opus teacher head0.025
GPT teacher head0.253
Teacher spread0.228 · how far apart the two teachers sit on this one work
Validation statusscore_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from it

Classification

machine, unvalidated

Machine predicted; a candidate call from one source (direct Gemma or distilled Codex), not a consensus.

The models applied no category: nothing in the taxonomy fit this work.
Study designBench or experimental
Domainnot available
GenreEmpirical

How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".

Quick stats

Citations0
Published2025
Admission routes1
Has abstractyes

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