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Record W4410122829 · doi:10.1227/neu.0000000000003485

Timing of Gastrostomy Relative to Tracheostomy After Complete Cervical Spinal Cord Injury: Impact on Hospitalization Outcomes and Complication Rates

2025· article· en· W4410122829 on OpenAlexaff
Armaan K. Malhotra, Avery B. Nathens, Eva Y. Yuan, Yingshi He, François Mathieu, Michael C. Sklar, Jefferson R. Wilson, Jetan H. Badhiwala

Bibliographic record

VenueNeurosurgery · 2025
Typearticle
Languageen
FieldNursing
TopicClinical Nutrition and Gastroenterology
Canadian institutionsSt. Michael's HospitalHealth Sciences CentreSunnybrook Health Science CentrePublic Health OntarioUniversity of Toronto
Fundersnot available
KeywordsMedicineGastrostomyMechanical ventilationPropensity score matchingRetrospective cohort studySpinal cord injuryIntensive care unitSurgeryIncidence (geometry)Univariate analysisComplicationTracheotomyAnesthesiaMultivariate analysisSpinal cordInternal medicine

Abstract

fetched live from OpenAlex

BACKGROUND AND OBJECTIVES: Tracheostomy and gastrostomy are frequently performed to facilitate prolonged ventilation and nutritional support in spinal cord injury (SCI) patients. The aim of this study was to evaluate the impact of gastrostomy timing relative to tracheostomy on in-hospital outcomes and complications in complete traumatic cervical SCI patients. METHODS: A multicenter retrospective observational study was performed using data from the Trauma Quality Improvement Program of the American College of Surgeons, between 2010 and 2020. The study included complete traumatic cervical SCI patients who underwent both tracheostomy and gastrostomy. Gastrostomy timing was categorized relative to tracheostomy timing as same-day (within 24 hours of tracheostomy) and delayed (more than 24 hours after tracheostomy). Outcomes of interest included intensive care unit (ICU) and hospital length of stay (LOS), mechanical ventilation duration, incidence of major in-hospital complications, immobility complications, and surgical site infections. Univariate and multivariable models were constructed to assess associations. We conducted a sensitivity analysis using propensity score matching to determine the robustness of our findings. RESULTS: Of 2958 patients included, 2168 underwent same-day tracheostomy and gastrostomy and 790 underwent delayed gastrostomy after tracheostomy. Patients in the same-day group had significantly shorter ICU and hospital LOS and reduced mechanical ventilation duration (adjusted mean difference [MD] -5.83, 95% CI -7.51 to -4.16, P < .001, adjusted MD -8.98, 95% CI -11.33 to -6.63, P < .001, and adjusted MD -5.93, 95% CI -7.80 to -4.07, P < .001, respectively). No evident difference was noted in the occurrence of major hospital adverse events between the groups. The sensitivity analysis recapitulated the primary analysis findings, demonstrating the consistency and robustness of effect estimates. CONCLUSION: Same-day tracheostomy and gastrostomy in complete traumatic cervical SCI patients was associated with better outcomes than delayed gastrostomy. Specifically, grouping these procedures may shorten ICU and overall hospital LOS, and reduce ventilation duration.

Fetched live from OpenAlex and de-inverted. Abstracts are not stored in this database: the inverted indexes are 8.6 GB of the frame’s 9.3 GB of text, and the host has 13 GB free.

How this classification was reachedexpand

Full frame machine prediction

Teacher imitation

Not calibrated prevalence, not ground truth. Human validation pending. The Gemma side is a direct model label for every work in the frame, read from the title-only record. The Codex side is a classifier learned from the 10,348 direct Codex labels and calibrated to design-weighted sample rates; fields without enough sample support carry no Codex call. Candidate is the union of the two sides; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels.

metaresearch head score (Codex)0.001
metaresearch head score (Gemma)0.008
Version: metacan-v3-hybrid-931329e0061cValidation status: machine_predicted_unvalidated
Candidate categoriesnone
Consensus categoriesnone
DomainCandidate signal: none · Consensus signal: none
Study designCandidate signal: Observational · Consensus signal: Observational
GenreCandidate signal: Empirical · Consensus signal: Empirical
Teacher disagreement score0.004
Threshold uncertainty score0.007

Distilled classifier scores by category (both heads)

CategoryCodexGemma
Metaresearch0.0010.008
Meta-epidemiology (narrow)0.0000.000
Meta-epidemiology (broad)0.0000.001
Bibliometrics0.0010.001
Science and technology studies0.0000.000
Scholarly communication0.0010.000
Open science0.0000.000
Research integrity0.0000.001
Insufficient payload (model declined to judge)0.0010.000

Machine scores (provisional)

The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.

Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.

Opus teacher head0.037
GPT teacher head0.371
Teacher spread0.334 · how far apart the two teachers sit on this one work
Validation statusscore_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from it

Classification

machine, unvalidated

Machine predicted; a candidate call from one source (direct Gemma or distilled Codex), not a consensus.

The models applied no category: nothing in the taxonomy fit this work.
Study designObservational
Domainnot available
GenreEmpirical

How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".

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Citations0
Published2025
Admission routes1
Has abstractyes

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