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Global Trends and Hotspots in Dulaglutide in the Fields of Diabetes, Obesity, and Cardiovascular Research: A Bibliometric Analysis

2025· article· en· W4410132717 on OpenAlex

Why this work is in the frame

A frame that forgets how it found something cannot be audited. These are the routes that admitted this work.

aboutThe title or abstract carries a Canadian signal from the geographic lexicon.
no affNo Canadian affiliation: this work is invisible to an affiliation-only frame.
No Canadian affiliation. An affiliation-only frame, the usual design, would never have seen this work. It is one of the works that make the case for inverting the frame.

Bibliographic record

VenueCurrent Bioactive Compounds · 2025
Typearticle
Languageen
FieldMedicine
TopicDiabetes Treatment and Management
Canadian institutionsnot available
Fundersnot available
KeywordsDulaglutideObesityDiabetes mellitusMedicineGeographyInternal medicineType 2 diabetesEndocrinology

Abstract

fetched live from OpenAlex

Aims: Dulaglutide, a glucagon-like peptide-1 (GLP-1) receptor agonist, has captured significant attention in the fields of diabetes, obesity, and cardiovascular research. This scientometric analysis was to identify global trends and hotspots in Dulaglutide research (DGR). Methods: A comprehensive search of the Scopus database was conducted to retrieve Englishlanguage data-driven studies published from the inception of the DGR from 2010 to December 2023. The collected data were subsequently analyzed using VOSviewer and Bibliometrix software. This study sheds light on the intellectual structure of the DGR, which includes identifying key research areas, influential authors, and collaborations, as well as the conceptual structure comprising the identified themes and trends within DGR. Results: The study identified a significant growth in DGR, with the United States, China, and the United Kingdom leading in research output. Canada exhibited strong international collaboration. A small group of highly productive authors contributed disproportionately to the literature, consistent with Lotka’s law. Research trends have evolved from broad themes in cardiovascular health to more specialized studies focusing on the drug’s mechanisms, comparative effectiveness, and emerging applications, such as non-alcoholic fatty liver disease. Citation analysis revealed cardiovascular outcomes, real-world effectiveness, and GLP-1 receptor interactions are among the most researched areas. Conclusion: DGR is a rapidly expanding field with shifting priorities from general diabetes management to specific pharmacological and clinical outcomes. The findings underscore the need for more diverse geographic representation in research and highlight knowledge gaps that future studies should address. This bibliometric analysis provides valuable insights into the intellectual landscape of Dulaglutide research, aiding future investigations and clinical applications.

Fetched live from OpenAlex and de-inverted. Abstracts are not stored in this database: the inverted indexes are 8.6 GB of the frame’s 9.3 GB of text, and the host has 13 GB free.

Full frame distilled prediction

Teacher imitation

Not calibrated prevalence, not ground truth. Human validation pending. Learned from the 10,348 direct Codex labels and 10,348 direct Gemma labels. Candidate is the union of thresholded teacher heads; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels or direct frontier model labels.

metaresearch head score (Codex)0.001
metaresearch head score (Gemma)0.000
Version: codex-gemma-dda1882f352aValidation status: machine_predicted_unvalidated
Candidate categoriesBibliometrics
Consensus categoriesBibliometrics
DomainCandidate signal: none · Consensus signal: none
Study designCandidate signal: Observational · Consensus signal: Observational
GenreCandidate signal: Empirical · Consensus signal: Empirical
Teacher disagreement score0.140
Threshold uncertainty score0.976

Codex and Gemma teacher scores by category

CategoryCodexGemma
Metaresearch0.0010.000
Meta-epidemiology (narrow)0.0000.000
Meta-epidemiology (broad)0.0010.000
Bibliometrics0.0350.104
Science and technology studies0.0000.000
Scholarly communication0.0000.000
Open science0.0000.000
Research integrity0.0000.000
Insufficient payload (model declined to judge)0.0000.000

Machine scores (provisional)

The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.

Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.

Opus teacher head0.062
GPT teacher head0.366
Teacher spread0.305 · how far apart the two teachers sit on this one work
Validation statusscore_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from it