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Record W4410153786 · doi:10.1371/journal.pone.0323007

Exploration of combined factors related to quality of life after knee replacement surgery

2025· article· en· W4410153786 on OpenAlexaboutno aff
Kohki Santoh, Hayato Shigetoh, Hiroaki Yamano, Kohtaroh Torizawa, Hiroshi Takasaki, Daisuke Uritani

Bibliographic record

VenuePLoS ONE · 2025
Typearticle
Languageen
FieldMedicine
TopicTotal Knee Arthroplasty Outcomes
Canadian institutionsnot available
Fundersnot available
KeywordsWOMACMedicineOsteoarthritisQuality of life (healthcare)Physical therapyJoint replacementKnee replacementArthroplastyInternal medicineSurgeryAlternative medicine

Abstract

fetched live from OpenAlex

In this study, we aimed to identify combined factors associated with lower postoperative quality of life (QOL) in knee replacement (KR) patients, utilising data from the Osteoarthritis Initiative (OAI) database. The data of 44 individuals from the OAI who underwent KR surgery was included in this study. Preoperative baseline data, including demographic information, comorbidities, depressive symptoms, knee-joint symptoms, and health-related QOL, were analysed using association rule analysis to identify single and combined factors linked to low postoperative QOL that were assessed with Short Form-12. Preoperative factors such as comorbidities, high Western Ontario and McMaster Universities Osteoarthritis Index (WOMAC)-pain scores, poor physical function, and older age were strongly associated with lower postoperative physical component scores (PCS) at 2 years. When combined, these factors showed even stronger associations with lower PCS. No significant associations were found with PCS and mental component scores (MCS) at 1 and 2 years postoperatively. Our findings emphasize the importance of evaluating combined preoperative factors, including comorbidities, pain levels, physical function, and age, as they may be associated with lower postoperative QOL in patients who underwent KR. Considering combined factors, rather than assessing single factors in isolation, may provide a more appropriate understanding of postoperative outcomes.

Fetched live from OpenAlex and de-inverted. Abstracts are not stored in this database: the inverted indexes are 8.6 GB of the frame’s 9.3 GB of text, and the host has 13 GB free.

How this classification was reachedexpand

Full frame machine prediction

Teacher imitation

Not calibrated prevalence, not ground truth. Human validation pending. The Gemma side is a direct model label for every work in the frame, read from the title-only record. The Codex side is a classifier learned from the 10,348 direct Codex labels and calibrated to design-weighted sample rates; fields without enough sample support carry no Codex call. Candidate is the union of the two sides; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels.

metaresearch head score (Codex)0.002
metaresearch head score (Gemma)0.007
Version: metacan-v3-hybrid-931329e0061cValidation status: machine_predicted_unvalidated
Candidate categoriesnone
Consensus categoriesnone
DomainCandidate signal: none · Consensus signal: none
Study designCandidate signal: Observational · Consensus signal: Observational
GenreCandidate signal: Empirical · Consensus signal: Empirical
Teacher disagreement score0.002
Threshold uncertainty score0.009

Distilled classifier scores by category (both heads)

CategoryCodexGemma
Metaresearch0.0020.007
Meta-epidemiology (narrow)0.0000.000
Meta-epidemiology (broad)0.0010.001
Bibliometrics0.0020.002
Science and technology studies0.0000.000
Scholarly communication0.0010.001
Open science0.0000.001
Research integrity0.0000.001
Insufficient payload (model declined to judge)0.0010.000

Machine scores (provisional)

The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.

Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.

Opus teacher head0.078
GPT teacher head0.295
Teacher spread0.217 · how far apart the two teachers sit on this one work
Validation statusscore_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from it

Classification

machine, unvalidated

Machine predicted; a candidate call from one source (direct Gemma or distilled Codex), not a consensus.

The models applied no category: nothing in the taxonomy fit this work.
Study designObservational
Domainnot available
GenreEmpirical

How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".

Quick stats

Citations2
Published2025
Admission routes1
Has abstractyes

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