Heart Conditioning as a Healthy Strategy in Management of Cardiac Enlargement
Bibliographic record
Abstract
Background: Remote ischemic conditioning (RIC) is widely recognized for its cardioprotective effects in the context of ischemic heart disease. Lately, it has been shown that heart conditioning can be utilized as a healthy strategy in the reversion of disease and aging. In this regard, we examine the impact of RIC on patients with cardiac enlargement. Methods: Forty-four patients with cardiac enlargement were prospectively enrolled and randomly assigned into RIC group (n = 22) and control group (n = 22). RIC protocol is 3-min inflation/deflation of the blood pressure cuff applied in the upper arm to create transient arm ischemia. RIC treatment was performed once a day for 1 year. Left atrial and ventricular dimensions and left ventricular ejection fraction (LVEF) were all assessed in two groups. Results: RIC was well-tolerated. After 1 year treatment, left atrial and ventricular dimensions were significantly decreased in the RIC group. Moreover, LVEF showed a significant increase, from 46.24% to 56.45% (P < 0.0001). Conclusion: The research indicates that a year-long healthy regimen of RIC treatment may effectively reverse cardiac enlargement, thereby endorsing the broader implementation of RIC in the daily routines of these patients.
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How this classification was reachedexpand
Full frame distilled prediction
Teacher imitationNot calibrated prevalence, not ground truth. Human validation pending. Learned from the 10,348 direct Codex labels and 10,348 direct Gemma labels. Candidate is the union of thresholded teacher heads; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels or direct frontier model labels.
Codex and Gemma teacher scores by category
| Category | Codex | Gemma |
|---|---|---|
| Metaresearch | 0.002 | 0.000 |
| Meta-epidemiology (narrow) | 0.000 | 0.000 |
| Meta-epidemiology (broad) | 0.001 | 0.000 |
| Bibliometrics | 0.000 | 0.001 |
| Science and technology studies | 0.000 | 0.000 |
| Scholarly communication | 0.000 | 0.000 |
| Open science | 0.000 | 0.000 |
| Research integrity | 0.000 | 0.000 |
| Insufficient payload (model declined to judge) | 0.000 | 0.000 |
Machine scores (provisional)
The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.
Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.
score_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from itClassification
machine, unvalidatedMachine predicted; a candidate call from one teacher head, not a consensus.
How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".