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Record W4410161295 · doi:10.1038/s41467-025-56910-x

Characterising acute and chronic care needs: insights from the Global Burden of Disease Study 2019

2025· article· en· W4410161295 on OpenAlexafffund
Masayuki Teramoto

Bibliographic record

VenueNature Communications · 2025
Typearticle
Languageen
FieldMedicine
TopicChronic Disease Management Strategies
Canadian institutionsAlberta Health ServicesSt. Thomas HospitalUniversity of CalgaryQueen's UniversityUniversity of AlbertaManitoba HealthCentre for Advancing Health OutcomesUniversity of WindsorDalhousie UniversityUniversity of OttawaMcGill UniversityPublic Health Agency of CanadaPopulation Health Research InstituteWestern UniversityUniversity of TorontoHamilton Health SciencesUniversity of British ColumbiaUniversity of ManitobaSt. Joseph’s Healthcare HamiltonUniversity of WaterlooMcMaster UniversityUniversité de MontréalUniversity of New BrunswickUniversity of SaskatchewanLawson Health Research Institute
FundersBiotechnology Industry Research Assistance CouncilFundação para a Ciência e a TecnologiaNational Health and Medical Research CouncilMedical Research CouncilDepartment of Epidemiology, Biostatistics and Occupational Health, McGill UniversityScience and Engineering Research BoardDirectorate for Mathematical and Physical SciencesMadda Walabu UniversityWestern Sydney UniversityFogarty International CenterIdorsia PharmaceuticalsApplied Molecular Biosciences UnitI.M. Sechenov First Moscow State Medical UniversityUniversitatea de Medicină şi Farmacie "Carol Davila" BucureştiFakultet Medicinskih Nauka, Univerziteta U KragujevcuKhulna UniversityCase Western Reserve UniversityInstitute for Health Metrics and EvaluationUniversity of SydneyUniversity of Agriculture, FaisalabadGuilan University of Medical SciencesMasarykova UniverzitaCabrini FoundationIndian Institute of Technology DelhiShaqra UniversityChina Medical UniversityUniversiteit StellenboschUniversity of DhakaDirectorate for Biological SciencesGöteborgs UniversitetLung Foundation AustraliaKing's College LondonImperial College LondonShiraz UniversityUniversidade Federal de Minas GeraisNational Institutes of HealthChinese University of Hong KongCharotar University of Science and TechnologyTaipei Medical UniversityTehran University of Medical Sciences and Health ServicesTsinghua UniversityAteneo de Manila UniversityKing Abdulaziz UniversityIsfahan University of Medical SciencesMinistero della SaluteCharles Sturt UniversityScience and Technology Development FundSRM Institute of Science and TechnologyInstitute for Advanced Studies in Basic SciencesPohang University of Science and TechnologyShiraz University of Medical SciencesAin Shams UniversityAcademy of Scientific Research and TechnologyDeakin UniversityShaheed Benazir Bhutto UniversityUniversity College LondonIndian Council of Medical ResearchUniversity of Central FloridaResearch Institute for Endocrine Sciences, Shahid Beheshti University of Medical SciencesUniversity of TasmaniaArthritis AustraliaUniversity of AlbertaNational Human Genome Research InstituteMacquarie UniversityThe Wellcome Trust DBT India AllianceNational Institute for Health and Care ResearchSanjay Gandhi Postgraduate Institute of Medical SciencesAsia UniversityUniversity of PretoriaUniversity of New South WalesJawaharlal Nehru UniversityDepartment of Science and Technology, Ministry of Science and Technology, IndiaNeyshabur University of Medical SciencesSouth African Medical Research CouncilKasturba Medical College, ManipalAsian Institute of Medicine, Science and TechnologySydney Medical SchoolAstraZenecaEuropean CommissionUniversity of TsukubaShahrekord University of Medical SciencesRMIT UniversityKermanshah University of Medical SciencesHCF Research FoundationU.S. Department of Veterans AffairsRafsanjan University of Medical SciencesUniversity of Engineering and Technology, LahoreRegeneron PharmaceuticalsShahrekord UniversityMylanNankai UniversityFresenius Medical Care North AmericaDivision of Mathematical SciencesTaibah UniversityTrường Đại học Duy TânWellcome TrustSecretaría Nacional de Ciencia, Tecnología e InnovaciónBanaras Hindu UniversityFederation University AustraliaJazan UniversityAlexion PharmaceuticalsUniversity of OtagoAuckland University of Technology, New ZealandLondon School of Hygiene and Tropical MedicineNational Institute for Research in TuberculosisMcGill UniversityInternational Parkinson and Movement Disorder SocietyAlexander von Humboldt-StiftungSanofiAmgenUniversità degli Studi di SassariPfizerEli Lilly and CompanyDepartment of Biotechnology, Ministry of Science and Technology, IndiaEmory University
KeywordsMedicineMultimorbidityChronic diseaseAcute careBurden of diseaseChronic conditionHealth careLong-term careHealthcare systemGerontologyDisease burdenChronic careDiseaseIntensive care medicinePsychiatryInternal medicine

Abstract

fetched live from OpenAlex

Chronic care manages long-term, progressive conditions, while acute care addresses short-term conditions. Chronic conditions increasingly strain health systems, which are often unprepared for these demands. This study examines the burden of conditions requiring acute versus chronic care, including sequelae. Conditions and sequelae from the Global Burden of Diseases Study 2019 were classified into acute or chronic care categories. Data were analysed by age, sex, and socio-demographic index, presenting total numbers and contributions to burden metrics such as Disability-Adjusted Life Years (DALYs), Years Lived with Disability (YLD), and Years of Life Lost (YLL). Approximately 68% of DALYs were attributed to chronic care, while 27% were due to acute care. Chronic care needs increased with age, representing 86% of YLDs and 71% of YLLs, and accounting for 93% of YLDs from sequelae. These findings highlight that chronic care needs far exceed acute care needs globally, necessitating health systems to adapt accordingly. Chronic care manages long-term, progressive conditions, while acute care handles short-term ones. Here, authors show chronic conditions account for most of the global health burden, with 68% of DALYs and 93% of YLDs attributed to chronic care needs.

Fetched live from OpenAlex and de-inverted. Abstracts are not stored in this database: the inverted indexes are 8.6 GB of the frame’s 9.3 GB of text, and the host has 13 GB free.

How this classification was reachedexpand

Full frame machine prediction

Teacher imitation

Not calibrated prevalence, not ground truth. Human validation pending. The Gemma side is a direct model label for every work in the frame, read from the title-only record. The Codex side is a classifier learned from the 10,348 direct Codex labels and calibrated to design-weighted sample rates; fields without enough sample support carry no Codex call. Candidate is the union of the two sides; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels.

metaresearch head score (Codex)0.002
metaresearch head score (Gemma)0.005
Version: metacan-v3-hybrid-931329e0061cValidation status: machine_predicted_unvalidated
Candidate categoriesnone
Consensus categoriesnone
DomainCandidate signal: none · Consensus signal: none
Study designCandidate signal: Observational · Consensus signal: Observational
GenreCandidate signal: Empirical · Consensus signal: Empirical
Teacher disagreement score0.023
Threshold uncertainty score0.046

Distilled classifier scores by category (both heads)

CategoryCodexGemma
Metaresearch0.0020.005
Meta-epidemiology (narrow)0.0000.000
Meta-epidemiology (broad)0.0000.001
Bibliometrics0.0030.006
Science and technology studies0.0000.000
Scholarly communication0.0010.001
Open science0.0000.002
Research integrity0.0000.001
Insufficient payload (model declined to judge)0.0030.000

Machine scores (provisional)

The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.

Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.

Opus teacher head0.015
GPT teacher head0.339
Teacher spread0.324 · how far apart the two teachers sit on this one work
Validation statusscore_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from it

Classification

machine, unvalidated

Machine predicted; a candidate call from one source (direct Gemma or distilled Codex), not a consensus.

The models applied no category: nothing in the taxonomy fit this work.
Study designObservational
Domainnot available
GenreEmpirical

How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".

Quick stats

Citations26
Published2025
Admission routes2
Has abstractyes

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