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Record W4410199010 · doi:10.1016/j.cdnut.2025.107458

Hemoglobin Concentrations and Prevalence of Anemia During Pregnancy: Results from the Brazilian Maternal and Child Nutrition Consortium

2025· article· en· W4410199010 on OpenAlex
Nathalia Freitas-Costa, Thaís Rangel Bousquet Carrilho, Paula Costa, Helena Mendes Constante, Elizabeth Fujimori, Ana Paula Sayuri Sato, Gilberto Kac

Why this work is in the frame

A frame that forgets how it found something cannot be audited. These are the routes that admitted this work.

affAt least one author lists a Canadian institution in the pinned OpenAlex snapshot.
fundA Canadian funder is recorded on the work.

Bibliographic record

VenueCurrent Developments in Nutrition · 2025
Typearticle
Languageen
FieldMedicine
TopicIron Metabolism and Disorders
Canadian institutionsUniversity of British Columbia
FundersUniversidade Federal do Rio de JaneiroConselho Nacional de Desenvolvimento Científico e TecnológicoFundação Carlos Chagas Filho de Amparo à Pesquisa do Estado do Rio de JaneiroMichael Smith Health Research BCUniversidade Federal do Espírito SantoUniversidade Federal de PelotasUniversidade de São PauloNational Research Council
KeywordsPregnancyAnemiaHemoglobinMedicineObstetricsEnvironmental healthPediatricsBiologyInternal medicine

Abstract

fetched live from OpenAlex

Background Anemia is a common among pregnant women from low- and middle-income countries, but national estimates are scarce. This study assessed hemoglobin (Hb) concentrations and the anemia prevalence in Brazil. Methods Data included 12,287 pregnant women aged 15-49 years and 17,967 measurements from seven studies (2007-2014) participating in the Brazilian Maternal and Child Nutrition Consortium. Hb (g/dL) was obtained from medical records (six studies, 17,565 measurements) or capillary blood samples (one study, 402 measurements). Hb <11, <10.5, and <11 g/dL were used to define anemia at the first, second, and third trimesters using the 2024 World Health Organization guideline. Identification of implausible Hb values and heterogeneity analysis were performed. We estimated medians and interquartile ranges for the Hb concentration and prevalence and 95% confidence intervals (CI) of anemia according to maternal pre-pregnancy body mass index, age and education, gestational trimester, and year of data collection. Results Median Hb was 12.0 (95%CI: 11.2-12.8) g/dL; no differences were observed according to the studied co-variables. Anemia prevalence was 14.1% (95%CI: 13.6-14.6), and highest during 2013 (27.9%; [95%CI: 17.3-38.6]) and in the third trimester (23.5% [95%CI: 22.5-24.6]). Higher anemia prevalence in the third compared to the first trimester was also observed among women aged 15-19 (1 st : 8.02% [95%CI: 6.2-9.9]; 3 rd : 28.1% [95%CI: 25.4-30.8]) than those aged 20-49 years (1 st : 6.5%; [5.8-7.2]; 3 rd : 22.6% [95%CI: 21.4-23.7]). Anemia prevalence for those with education ≤ 4 years (15.9%; 95%CI: 14.1-17.8) and women with pre-pregnancy underweight (19.2%; 95%CI: 15.9-22.4) and normal weight (15.3%; 95%CI: 14.4-16.2) were higher than those with 9-11 (13.1%; 95%CI: 12.4-13.8) and 12-18 years (10.3%; 95%CI: 9.2-11.0), and overweight (12.2%; 95%CI:10.8-13.6) and obesity (9.9%; 95%CI: 8.1-11.7). Conclusion Anemia was higher in adolescents compared to older women and in the third trimester compared to the first, underscoring the need for targeted monitoring during these periods.

Fetched live from OpenAlex and de-inverted. Abstracts are not stored in this database: the inverted indexes are 8.6 GB of the frame’s 9.3 GB of text, and the host has 13 GB free.

Full frame distilled prediction

Teacher imitation

Not calibrated prevalence, not ground truth. Human validation pending. Learned from the 10,348 direct Codex labels and 10,348 direct Gemma labels. Candidate is the union of thresholded teacher heads; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels or direct frontier model labels.

metaresearch head score (Codex)0.000
metaresearch head score (Gemma)0.000
Version: codex-gemma-dda1882f352aValidation status: machine_predicted_unvalidated
Candidate categoriesnone
Consensus categoriesnone
DomainCandidate signal: none · Consensus signal: none
Study designCandidate signal: Observational · Consensus signal: Observational
GenreCandidate signal: Empirical · Consensus signal: Empirical
Teacher disagreement score0.023
Threshold uncertainty score0.391

Codex and Gemma teacher scores by category

CategoryCodexGemma
Metaresearch0.0000.000
Meta-epidemiology (narrow)0.0000.000
Meta-epidemiology (broad)0.0000.000
Bibliometrics0.0000.000
Science and technology studies0.0000.000
Scholarly communication0.0000.000
Open science0.0000.000
Research integrity0.0000.000
Insufficient payload (model declined to judge)0.0000.000

Machine scores (provisional)

The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.

Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.

Opus teacher head0.011
GPT teacher head0.269
Teacher spread0.259 · how far apart the two teachers sit on this one work
Validation statusscore_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from it