MétaCan
Menu
← Back to cohort
Record W4410216180 · doi:10.1101/2025.05.01.651648

Within- and Between-Assessor Reliability of Lower-Limb Inter-Joint Coordination During Gait in Individuals With and Without Cerebral Palsy

2025· preprint· en· W4410216180 on OpenAlexaff
C Picard, Yosra Cherni, Mickael Fonseca, Léna Carcreff, Fabien Leboeuf, Stéphane Armand

Bibliographic record

VenuebioRxiv (Cold Spring Harbor Laboratory) · 2025
Typepreprint
Languageen
FieldMedicine
TopicCerebral Palsy and Movement Disorders
Canadian institutionsUniversité de Montréal
Fundersnot available
KeywordsCerebral palsyGaitPhysical medicine and rehabilitationReliability (semiconductor)Joint (building)PsychologyMedicineEngineering

Abstract

fetched live from OpenAlex

Abstract Background Inter-joint coordination plays a key role in walking, particularly in people with cerebral palsy (CP), who experience altered movement patterns. The Continuous Relative Phase (CRP) method quantifies lower-limb coordination by assessing the phase relationships between joints. However, the reliability of CRP measurements during walking in individuals with CP remains unexplored, and may be affected by measurement variability due to marker placement errors, soft tissue artifacts, and natural movement fluctuations. Quantifying this reliability is important for appropriate clinical comparisons. This study aimed to quantify within- and between-assessor reliability of lower-limb CRP measurements in individuals with CP and their non-impaired (NI) peers. Methods CP (n=19, age=18.4±7.3 years, GMFCS I–III) and NI (n=19, age=18.3±11.2 years) individuals completed two gait assessment sessions, each including 3D motion capture of at least 10 walking trials. Two trained assessors independently placed reflective markers and conducted gait analyses. Standard error of measurement (SEM) and minimal detectable change (MDC) were computed for knee-hip and ankle-knee coordination across gait subphases. Findings The SEM and MDC were lower for knee-hip than ankle-knee coordination, suggesting higher measurement reliability for proximal joint coupling. For knee-hip coordination, MDC reached 15.1±0.7°(CP) and 9.3±0.6°(NI) between assessors, and 23.8±3.0°(CP) and 9.1±1.6°(NI) within assessors. For ankle-knee coordination, MDC reached 29.0±2.6°(CP) and 25.0±3.5°(NI) between assessors, peaking at 47.3±10.9°(CP) and 28.6±1.5°(NI) in mid-swing within assessors. Interpretation This study provides the first metrological reference for reliability of CRP-based inter-joint coordination during gait in CP. Results showed poor reliability, emphazing that such measurements must be interpreted with caution. Highlights - Knee-hip showed greater reliability than ankle-knee coordination across gait phases - Cerebral palsy individuals showed higher variability than non-impaired peers The beginning and the end of gait cycle showed the poorest reliability Pre-post comparisons should account for MDC thresholds to avoid misinterpretation

Fetched live from OpenAlex and de-inverted. Abstracts are not stored in this database: the inverted indexes are 8.6 GB of the frame’s 9.3 GB of text, and the host has 13 GB free.

How this classification was reachedexpand

Full frame machine prediction

Teacher imitation

Not calibrated prevalence, not ground truth. Human validation pending. The Gemma side is a direct model label for every work in the frame, read from the title-only record. The Codex side is a classifier learned from the 10,348 direct Codex labels and calibrated to design-weighted sample rates; fields without enough sample support carry no Codex call. Candidate is the union of the two sides; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels.

metaresearch head score (Codex)0.003
metaresearch head score (Gemma)0.011
Version: metacan-v3-hybrid-931329e0061cValidation status: machine_predicted_unvalidated
Candidate categoriesnone
Consensus categoriesnone
DomainCandidate signal: none · Consensus signal: none
Study designCandidate signal: Observational · Consensus signal: Observational
GenreCandidate signal: Empirical · Consensus signal: Empirical
Teacher disagreement score0.009
Threshold uncertainty score0.017

Distilled classifier scores by category (both heads)

CategoryCodexGemma
Metaresearch0.0030.011
Meta-epidemiology (narrow)0.0000.000
Meta-epidemiology (broad)0.0000.000
Bibliometrics0.0010.000
Science and technology studies0.0000.000
Scholarly communication0.0010.000
Open science0.0010.001
Research integrity0.0000.000
Insufficient payload (model declined to judge)0.0010.000

Machine scores (provisional)

The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.

Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.

Opus teacher head0.013
GPT teacher head0.244
Teacher spread0.230 · how far apart the two teachers sit on this one work
Validation statusscore_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from it

Classification

machine, unvalidated

Machine predicted; a candidate call from one source (direct Gemma or distilled Codex), not a consensus.

The models applied no category: nothing in the taxonomy fit this work.
Study designObservational
Domainnot available
GenreEmpirical

How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".

Quick stats

Citations0
Published2025
Admission routes1
Has abstractyes

Explore more

Same venuebioRxiv (Cold Spring Harbor Laboratory)→Same topicCerebral Palsy and Movement Disorders→French-language works237,207→