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Record W4410266644 · doi:10.1111/vsu.14267

Prognostic factors for short‐term survival of cats that experienced postattenuation neurologic signs after surgical attenuation of single congenital portosystemic shunts

2025· article· en· W4410266644 on OpenAlexaff
Ignacio Otero Balda, Laura E. Selmic, Polina Stamenova, Matthew Simpson, Victoria J. Lipscomb, Anne Kummeling, Nausikaa Devriendt, H. de Rooster, Katarzyna M. Grzywa, Mickey Tivers, Guillaume Chanoit, Adrien Maggiar, Jean‐Philippe Billet, Alberto Oramas, Ameet Singh, Ronan A. Mullins

Bibliographic record

VenueVeterinary Surgery · 2025
Typearticle
Languageen
FieldMedicine
TopicLiver Disease and Transplantation
Canadian institutionsUniversity of Guelph
Fundersnot available
KeywordsCATSMedicineRetrospective cohort studyPropofolClinical significanceMedical recordOdds ratioLogistic regressionPortosystemic shuntSurgeryInternal medicinePortal hypertension

Abstract

fetched live from OpenAlex

OBJECTIVE: To report 30-day survival of cats that experienced postattenuation neurologic signs (PANS) after surgical attenuation of a single congenital portosystemic shunt (cPSS), and to investigate prognostic factors for short-term survival. STUDY DESIGN: Multi-institutional retrospective study. SAMPLE POPULATION: A total of 59 cats with cPSS that experienced PANS. METHODS: The medical records of 10 institutions were retrospectively reviewed to identify cats that underwent cPSS attenuation from January 1, 2010 through June 30, 2023 and developed PANS within 7 days postoperatively. Exclusion criteria were cats with arteriovenous malformation and cats lost-to-follow-up prior to 30 days. Logistic regression identified factors associated with 30-day survival. Odds Ratios (OR) and 95% CIs were calculated. RESULTS: A total of 46 (78.0%) PANS-affected cats survived to 30 days. A total of 13 (50.0%) of 26 cats that experienced postattenuation seizures (PAS) survived to 30 days, with most non-surviving cats experiencing generalized PAS. Cats that experienced PAS (p < .01, OR: 0.015, 95% CI: <0.001-0.281) and treatment of PANS with propofol (p < .01, OR: 0.112, 95% CI: 0.022-0.569) were associated with decreased odds of 30-day survival. CONCLUSION: Most cats that experienced PANS survived to 30 days; however, short-term survival rate was worse for cats that experienced PAS. CLINICAL SIGNIFICANCE: The prognosis for cats that experience PANS is generally good but experiencing PAS and requiring treatment with propofol are negative prognostic factors.

Fetched live from OpenAlex and de-inverted. Abstracts are not stored in this database: the inverted indexes are 8.6 GB of the frame’s 9.3 GB of text, and the host has 13 GB free.

How this classification was reachedexpand

Full frame distilled prediction

Teacher imitation

Not calibrated prevalence, not ground truth. Human validation pending. Learned from the 10,348 direct Codex labels and 10,348 direct Gemma labels. Candidate is the union of thresholded teacher heads; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels or direct frontier model labels.

metaresearch head score (Codex)0.000
metaresearch head score (Gemma)0.000
Version: codex-gemma-dda1882f352aValidation status: machine_predicted_unvalidated
Candidate categoriesnone
Consensus categoriesnone
DomainCandidate signal: none · Consensus signal: none
Study designCandidate signal: Observational · Consensus signal: Observational
GenreCandidate signal: Empirical · Consensus signal: Empirical
Teacher disagreement score0.077
Threshold uncertainty score0.581

Codex and Gemma teacher scores by category

CategoryCodexGemma
Metaresearch0.0000.000
Meta-epidemiology (narrow)0.0000.000
Meta-epidemiology (broad)0.0000.000
Bibliometrics0.0000.000
Science and technology studies0.0000.000
Scholarly communication0.0000.000
Open science0.0000.000
Research integrity0.0000.000
Insufficient payload (model declined to judge)0.0000.000

Machine scores (provisional)

The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.

Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.

Opus teacher head0.075
GPT teacher head0.305
Teacher spread0.230 · how far apart the two teachers sit on this one work
Validation statusscore_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from it

Classification

machine, unvalidated

Machine predicted; a candidate call from one teacher head, not a consensus.

The models applied no category: nothing in the taxonomy fit this work.
Study designObservational
Domainnot available
GenreEmpirical

How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".

Quick stats

Citations1
Published2025
Admission routes1
Has abstractyes

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