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Record W4410267978 · doi:10.1164/rccm.202501-0280oc

Social Determinants of Health and Racial Disparities in Lung Function: Findings from the National Health and Nutrition Examination Survey, 2007–2012

2025· article· en· W4410267978 on OpenAlexafffund
Amin Adibi, Christopher Carlsten, Emily Brigham, Don D. Sin, Peter Loewen, Mohsen Sadatsafavi

Bibliographic record

VenueAmerican Journal of Respiratory and Critical Care Medicine · 2025
Typearticle
Languageen
FieldSocial Sciences
TopicHealth disparities and outcomes
Canadian institutionsSt. Paul's HospitalCentre for Advancing Health OutcomesUniversity of British Columbia
FundersCanadian Institutes of Health Research
KeywordsMedicineDemographyNational Health and Nutrition Examination SurveyEthnic groupHealth equityAsian americansObesityGerontologyMexican americansSocial determinants of healthPublic healthPopulationEnvironmental healthInternal medicine

Abstract

fetched live from OpenAlex

Abstract Rationale We hypothesized that the disproportionate impact of social determinants of health (SDoH) captured in survey data could help explain a larger proportion of racial gaps in lung function than previously reported. Objective To estimate the contribution of SDoH to racial gaps in lung function. Methods We defined a series of nested, increasingly healthy reference populations using data from the National Health and Nutrition Examination Survey, 2007–2012. Starting with nonsmokers without respiratory symptoms or diagnoses, we sequentially excluded those with confirmed occupational exposure to dust and/or fumes, physical inactivity, maternal or secondhand tobacco use, obesity, no home ownership, no insurance, lower education, and self-reported unhealthy diet. Across successive populations, we compared average age-, sex-, and height-adjusted differences in FEV1 and FVC between racial and ethnic minority groups and non-Hispanic White participants for adults (aged ≥20 yr) and children (aged 6–19 yr). Measurements and Main Results In successively healthier reference populations, the proportion of represented participants declined for non-Hispanic Black, Mexican American, and other Hispanic participants; increased for non-Hispanic White participants; and remained stable for non-Hispanic Asian participants. At baseline, adjusted FEV1 and FVC were similar for Mexican American and non-Hispanic White American participants but lower for other racial and ethnic minority groups. After excluding individuals with unfavorable SDoH, racial disparities in FEV1 and FVC decreased for non-Hispanic Black children (24.8% and 26.2%) and adults (26.3% and 19.4%), other Hispanic children (15.2% and 19.3%) and adults (85.9% and 12.4%), and non-Hispanic Asian children (6.6% and 12.5%), but they increased for non-Hispanic Asian adults (14.1% and 11.1%). Conclusions Unfavorable SDoH disproportionately affected non-Hispanic Black, Mexican American, and other Hispanic populations and explained a higher proportion of racial disparities in lung function than previously reported.

Fetched live from OpenAlex and de-inverted. Abstracts are not stored in this database: the inverted indexes are 8.6 GB of the frame’s 9.3 GB of text, and the host has 13 GB free.

How this classification was reachedexpand

Full frame machine prediction

Teacher imitation

Not calibrated prevalence, not ground truth. Human validation pending. The Gemma side is a direct model label for every work in the frame, read from the title-only record. The Codex side is a classifier learned from the 10,348 direct Codex labels and calibrated to design-weighted sample rates; fields without enough sample support carry no Codex call. Candidate is the union of the two sides; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels.

metaresearch head score (Codex)0.001
metaresearch head score (Gemma)0.003
Version: metacan-v3-hybrid-931329e0061cValidation status: machine_predicted_unvalidated
Candidate categoriesnone
Consensus categoriesnone
DomainCandidate signal: none · Consensus signal: none
Study designCandidate signal: Observational · Consensus signal: Observational
GenreCandidate signal: Empirical · Consensus signal: Empirical
Teacher disagreement score0.043
Threshold uncertainty score0.086

Distilled classifier scores by category (both heads)

CategoryCodexGemma
Metaresearch0.0010.003
Meta-epidemiology (narrow)0.0000.000
Meta-epidemiology (broad)0.0000.001
Bibliometrics0.0010.001
Science and technology studies0.0000.000
Scholarly communication0.0000.000
Open science0.0010.001
Research integrity0.0000.000
Insufficient payload (model declined to judge)0.0010.000

Machine scores (provisional)

The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.

Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.

Opus teacher head0.051
GPT teacher head0.415
Teacher spread0.364 · how far apart the two teachers sit on this one work
Validation statusscore_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from it

Classification

machine, unvalidated

Machine predicted; a candidate call from one source (direct Gemma or distilled Codex), not a consensus.

The models applied no category: nothing in the taxonomy fit this work.
Study designObservational
Domainnot available
GenreEmpirical

How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".

Quick stats

Citations4
Published2025
Admission routes2
Has abstractyes

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