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Record W4410269557 · doi:10.1093/pubmed/fdaf053

The COVID-19 pandemic’s impact on sexually transmitted infections and the modifying role of public health funding: an interrupted time series study

2025· article· en· W4410269557 on OpenAlexafffundabout
Naomi Schwartz, Stephen Hunter, Samantha M. Forbes, Dionne Gesink, Erin Hobin, Laura N. Anderson, Steven Rebellato, Roman Pabayo, Brendan T. Smith

Bibliographic record

VenueJournal of Public Health · 2025
Typearticle
Languageen
FieldImmunology and Microbiology
TopicReproductive tract infections research
Canadian institutionsImpactMcMaster UniversityUniversity of TorontoUniversity of Alberta
FundersCanadian Institutes of Health Research
KeywordsMedicinePublic healthGonorrheaSyphilisChlamydiaDemographyIncidence (geometry)PandemicRate ratioEnvironmental healthPopulationEpidemiologyInfectious disease (medical specialty)ImmunologyCoronavirus disease 2019 (COVID-19)Internal medicineHuman immunodeficiency virus (HIV)Disease

Abstract

fetched live from OpenAlex

BACKGROUND: This study investigated whether the COVID-19 pandemic was associated with changes in sexually transmitted infection (STI) incidence and trajectories in Ontario, Canada and the modifying role of public health funding for infectious and communicable diseases (ICD). METHODS: A repeated cross-sectional study was conducted using population-level age and sex standardized incidence of chlamydia, gonorrhea, and infectious syphilis by public health unit (PHU) in Ontario from January 2015-October 2022. A negative binomial regression interrupted time series analysis estimated trends in STI incidence rates pre- and post-pandemic-onset and whether associations differed by public health ICD funding per capita. RESULTS: There was an immediate reduction post- compared to pre-pandemic onset in chlamydia (Rate Ratio (RR) = 0.27, 95% confidence interval (CI): 0.21-0.35), gonorrhea (RR = 0.15, 95% CI: 0.02-0.94), and syphilis (RR = 0.16, 95% CI: 0.02-1.18). Post-pandemic onset, a dollar increase in PHU's ICD funding per capita was associated with greater incidence of chlamydia (RR = 1.10, 95% CI: 1.08-1.12), gonorrhea (RR = 1.14, 95% CI: 0.99-1.32) and syphilis (RR = 1.11, 95% CI: 0.97-1.28). Following this initial drop, trends in STI incidence did not differ importantly by ICD funding. CONCLUSIONS: Findings are consistent with a role of public health funding in mitigating observed decreases in STIs. Results suggest that public health funding plays a role in maintaining STI detection services during a public health emergency.

Fetched live from OpenAlex and de-inverted. Abstracts are not stored in this database: the inverted indexes are 8.6 GB of the frame’s 9.3 GB of text, and the host has 13 GB free.

How this classification was reachedexpand

Full frame machine prediction

Teacher imitation

Not calibrated prevalence, not ground truth. Human validation pending. The Gemma side is a direct model label for every work in the frame, read from the title-only record. The Codex side is a classifier learned from the 10,348 direct Codex labels and calibrated to design-weighted sample rates; fields without enough sample support carry no Codex call. Candidate is the union of the two sides; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels.

metaresearch head score (Codex)0.006
metaresearch head score (Gemma)0.015
Version: metacan-v3-hybrid-931329e0061cValidation status: machine_predicted_unvalidated
Candidate categoriesnone
Consensus categoriesnone
DomainCandidate signal: none · Consensus signal: none
Study designCandidate signal: Observational · Consensus signal: Observational
GenreCandidate signal: Empirical · Consensus signal: Empirical
Teacher disagreement score0.360
Threshold uncertainty score0.716

Distilled classifier scores by category (both heads)

CategoryCodexGemma
Metaresearch0.0060.015
Meta-epidemiology (narrow)0.0000.000
Meta-epidemiology (broad)0.0010.001
Bibliometrics0.0010.002
Science and technology studies0.0000.001
Scholarly communication0.0010.001
Open science0.0010.001
Research integrity0.0010.001
Insufficient payload (model declined to judge)0.0020.000

Machine scores (provisional)

The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.

Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.

Opus teacher head0.133
GPT teacher head0.437
Teacher spread0.304 · how far apart the two teachers sit on this one work
Validation statusscore_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from it

Classification

machine, unvalidated

Machine predicted; a candidate call from one source (direct Gemma or distilled Codex), not a consensus.

The models applied no category: nothing in the taxonomy fit this work.
Study designObservational
Domainnot available
GenreEmpirical

How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".

Quick stats

Citations4
Published2025
Admission routes3
Has abstractyes

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