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Record W4410271273 · doi:10.1093/pch/pxaf023

Developmental screening at 18 months using the Nipissing District Developmental Screen

2025· article· en· W4410271273 on OpenAlexafffundabout
Cornelia M. Borkhoff, Haris Imsirovic, Imaan Bayoumi, Kimberly M. Nurse, Teresa To, Mark Feldman, Eddy Lau, Braden Knight, Catherine S. Birken, Jonathon L. Maguire, Patricia C. Parkin

Bibliographic record

VenuePaediatrics & Child Health · 2025
Typearticle
Languageen
FieldMedicine
TopicInfant Development and Preterm Care
Canadian institutionsQueen's UniversityInstitute for Clinical Evaluative SciencesUniversity of TorontoSickKids FoundationHospital for Sick ChildrenPublic Health Ontario
FundersCanadian Institutes of Health ResearchSick Kids FoundationSt. Michael’s Hospital Foundation
KeywordsMedicineOptometry

Abstract

fetched live from OpenAlex

Objectives: The Canadian Paediatric Society recommends an enhanced 18-month visit, including the use of a developmental screening tool to stimulate discussion with parents about their child's development, and notes the Nipissing District Developmental Screen (NDDS) is a widely used tool. We examined the predictive validity of the NDDS in children at average-risk for developmental delay and the association between positive screening and health care utilization (HCU). Methods: Using a prospective design, parents completed the NDDS at the 18-month primary care visit in Toronto, Canada. Child health insurance number was used to link with health administrative databases to collect HCU data. We calculated screening test properties using later neurodevelopmental consultation as the criterion measure and used multivariable negative binomial regression to estimate adjusted rate ratios (aRR) for each HCU type. Results: Of 802 children (mean age 18 months), 35.5% screened NDDS positive. Mean age at follow-up was 8 years, 20 (2.5%) had a neurodevelopmental consultation, and 94 (11.7%) had a special paediatric consultation/assessment, including developmental and/or behavioural care. Screening test properties were: 50% sensitivity (95% CI 27%, 73%), 65% specificity (95% CI 61%, 68%), 35% false positive rate (95% CI 31%, 40%). A positive NDDS was associated with only 1 of 7 HCU types. Conclusions: The sensitivity and specificity of the NDDS is inadequate for a developmental screening tool at 18 months, and the false positive rate is unacceptably high. The screening test properties of other widely used developmental screening tools is discussed, noting their low sensitivity, higher specificity, and lower false positive rates. Trial registration: Clinicaltrials.gov (NCT01869530).

Fetched live from OpenAlex and de-inverted. Abstracts are not stored in this database: the inverted indexes are 8.6 GB of the frame’s 9.3 GB of text, and the host has 13 GB free.

How this classification was reachedexpand

Full frame machine prediction

Teacher imitation

Not calibrated prevalence, not ground truth. Human validation pending. The Gemma side is a direct model label for every work in the frame, read from the title-only record. The Codex side is a classifier learned from the 10,348 direct Codex labels and calibrated to design-weighted sample rates; fields without enough sample support carry no Codex call. Candidate is the union of the two sides; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels.

metaresearch head score (Codex)0.002
metaresearch head score (Gemma)0.007
Version: metacan-v3-hybrid-931329e0061cValidation status: machine_predicted_unvalidated
Candidate categoriesnone
Consensus categoriesnone
DomainCandidate signal: none · Consensus signal: none
Study designCandidate signal: Observational · Consensus signal: Observational
GenreCandidate signal: Empirical · Consensus signal: Empirical
Teacher disagreement score0.648
Threshold uncertainty score0.700

Distilled classifier scores by category (both heads)

CategoryCodexGemma
Metaresearch0.0020.007
Meta-epidemiology (narrow)0.0010.000
Meta-epidemiology (broad)0.0000.001
Bibliometrics0.0020.002
Science and technology studies0.0010.000
Scholarly communication0.0010.000
Open science0.0010.001
Research integrity0.0000.000
Insufficient payload (model declined to judge)0.0030.000

Machine scores (provisional)

The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.

Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.

Opus teacher head0.028
GPT teacher head0.297
Teacher spread0.269 · how far apart the two teachers sit on this one work
Validation statusscore_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from it

Classification

machine, unvalidated

Machine predicted; a candidate call from one source (direct Gemma or distilled Codex), not a consensus.

The models applied no category: nothing in the taxonomy fit this work.
Study designObservational
Domainnot available
GenreEmpirical

How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".

Quick stats

Citations1
Published2025
Admission routes3
Has abstractyes

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