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Record W4410274788 · doi:10.1101/2025.05.09.25325944

Effects of different exercise training program on post-exercise VO <sub>2</sub> kinetics and VO <sub>2</sub> recovery delay in stable patients with coronary heart disease

2025· preprint· en· W4410274788 on OpenAlexaff
Mathieu Gayda, Lukas-Daniel Trachsel, Pierre‐Marie Leprêtre, Florent Besnier, Maxime Boidin, Julie Lalongé, Louis Bherer, Martin Juneau, Anil Nigam

Bibliographic record

VenuemedRxiv · 2025
Typepreprint
Languageen
FieldMedicine
TopicCardiovascular and exercise physiology
Canadian institutionsUniversité de MontréalMontreal Heart Institute
Fundersnot available
KeywordsCardiologyTraining (meteorology)Internal medicineMedicinePhysical therapyCoronary heart diseasePhysical medicine and rehabilitationPhysics

Abstract

fetched live from OpenAlex

Abstract Post-exercise V̇O 2 kinetics and V̇O 2 recovery delay (RD) are clinical prognostic markers in cardiac patients, but have not been studied after exercise training in patients with coronary heart disease (CHD). We aimed to compare the effects of 12-weeks moderate-intensity continuous exercise training (MICET), low volume high-intensity interval training (LV-HIIT), or combined MICET/HIIT on O 2 deficit, post-exercise V̇O 2 kinetics, O 2 debt and V̇O 2 recovery delay (RD) in patients with CHD. Methods Patients with CHD were randomised in MICET, LV-HIIT or combined MICET/HIIT group for 12 weeks. Cardiopulmonary exercise test (CPET) parameters were assessed, and key exercise variables were calculated during and after exercise. CPET post-exercise kinetics time constant (r) (for V̇O 2 , V̇CO 2 , V̇ E and HR), O 2 deficit, O 2 debt and V̇O 2 recovery delay (RD) were calculated before and after training. Results A significant time effect (training) for r V̇O 2 (min) (p<0.05) was shown for all groups. Shorter r V̇O 2 values with small effect size (ES: 0.21 to 0.4) were noted for the combined MICET/HIIT and MICET groups. A significant time effect (p<0.01) was noted for O 2 debt that was increased after training (ES: 0.1 to 0.47). No significant statistical effect was shown for V̇O 2 RD and r V̇CO 2 , r V̇ E, r HR and O 2 deficit in all groups. Conclusions In patients with CHD, exercise training improved post-exercise V̇O 2 kinetic and the O 2 debt, with a higher impact of exercise dose (combined MICET/HIIT). Exercise training did not improved the V̇O 2 RD or other τ CPET recovery variables in CHD patients.

Fetched live from OpenAlex and de-inverted. Abstracts are not stored in this database: the inverted indexes are 8.6 GB of the frame’s 9.3 GB of text, and the host has 13 GB free.

How this classification was reachedexpand

Full frame machine prediction

Teacher imitation

Not calibrated prevalence, not ground truth. Human validation pending. The Gemma side is a direct model label for every work in the frame, read from the title-only record. The Codex side is a classifier learned from the 10,348 direct Codex labels and calibrated to design-weighted sample rates; fields without enough sample support carry no Codex call. Candidate is the union of the two sides; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels.

metaresearch head score (Codex)0.000
metaresearch head score (Gemma)0.001
Version: metacan-v3-hybrid-931329e0061cValidation status: machine_predicted_unvalidated
Candidate categoriesnone
Consensus categoriesnone
DomainCandidate signal: none · Consensus signal: none
Study designCandidate signal: Observational · Consensus signal: none
GenreCandidate signal: Empirical · Consensus signal: Empirical
Teacher disagreement score0.001
Threshold uncertainty score0.004

Distilled classifier scores by category (both heads)

CategoryCodexGemma
Metaresearch0.0000.001
Meta-epidemiology (narrow)0.0000.000
Meta-epidemiology (broad)0.0010.001
Bibliometrics0.0000.000
Science and technology studies0.0000.000
Scholarly communication0.0000.000
Open science0.0000.000
Research integrity0.0000.000
Insufficient payload (model declined to judge)0.0010.000

Machine scores (provisional)

The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.

Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.

Opus teacher head0.008
GPT teacher head0.225
Teacher spread0.217 · how far apart the two teachers sit on this one work
Validation statusscore_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from it

Classification

machine, unvalidated

Machine predicted; a candidate call from one source (direct Gemma or distilled Codex), not a consensus.

The models applied no category: nothing in the taxonomy fit this work.
Study designObservational
Domainnot available
GenreEmpirical

How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".

Quick stats

Citations0
Published2025
Admission routes1
Has abstractyes

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