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Record W4410287301 · doi:10.1093/ageing/afaf115

Validation of the standard assessment of global everyday activities (SAGEA) scale for dementia diagnosis

2025· article· en· W4410287301 on OpenAlexaffabout
Jolene Phelps, Dylan X. Guan, Koon Teo, Martin O’Donnell, Salim Yusuf, Jackie Bosch, Zahinoor Ismail, Eric E. Smith

Bibliographic record

VenueAge and Ageing · 2025
Typearticle
Languageen
FieldMedicine
TopicDementia and Cognitive Impairment Research
Canadian institutionsHamilton Health SciencesMcMaster UniversityPopulation Health Research InstituteUniversity of VictoriaUniversity of Calgary
Fundersnot available
KeywordsDementiaMedicineCognitionActivities of daily livingGerontologyQuality of life (healthcare)Cognitive impairmentClinical psychologyPsychiatryInternal medicineDisease

Abstract

fetched live from OpenAlex

BACKGROUND: Standardised questionnaires of cognitive symptoms and cognitive-related function can assist in diagnosing dementia. The Standardised Assessment of Global Everyday Activities (SAGEA) is a 15-item questionnaire, developed to measure functional status by capturing cognitive symptoms, basic and instrumental activities of daily living, participation in activites, and mobility. OBJECTIVE: The aim of this study was to validate the SAGEA as a tool for assessing cognitive dysfunction in dementia. METHODS: Participants with dementia, mild cognitive impairment (MCI) or subjective cognitive decline (SCD) were selected from the clinic-based Prospective Registry for Persons with Memory Symptoms (PROMPT), and cognitively asymptomatic, unimpaired controls were selected from the Canadian Platform for Research Online to Investigate Health, Quality of Life, Cognition, Behaviour, Function and Caregiving in Ageing study. RESULTS: SAGEA scores correlated well with the Lawton-Brody scale for instrumental activities of daily living (r = -0.68, P < 0.0001). SAGEA scores differed significantly across participant groups, highest for individuals with dementia (17.7 ± 8.59) followed by MCI (10.8 ± 9.10), SCD (8.07 ± 7.06) and controls (1.60 ± 2.07). The SAGEA classified dementia with an AUC of 0.97, sensitivity of 94.5% and specificity of 94.6% at a cut-off point of ≥6 points based on Youden's index. A dementia diagnosis algorithm based on the SAGEA distinguished dementia from controls with a sensitivity of 68% and specificity of 100%. CONCLUSIONS: This study supports the utility of the SAGEA as an adjunct to diagnosing dementia and a potentially useful screening tool.

Fetched live from OpenAlex and de-inverted. Abstracts are not stored in this database: the inverted indexes are 8.6 GB of the frame’s 9.3 GB of text, and the host has 13 GB free.

How this classification was reachedexpand

Full frame distilled prediction

Teacher imitation

Not calibrated prevalence, not ground truth. Human validation pending. Learned from the 10,348 direct Codex labels and 10,348 direct Gemma labels. Candidate is the union of thresholded teacher heads; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels or direct frontier model labels.

metaresearch head score (Codex)0.000
metaresearch head score (Gemma)0.000
Version: codex-gemma-dda1882f352aValidation status: machine_predicted_unvalidated
Candidate categoriesnone
Consensus categoriesnone
DomainCandidate signal: none · Consensus signal: none
Study designCandidate signal: Observational · Consensus signal: Observational
GenreCandidate signal: Empirical · Consensus signal: Empirical
Teacher disagreement score0.096
Threshold uncertainty score0.156

Codex and Gemma teacher scores by category

CategoryCodexGemma
Metaresearch0.0000.000
Meta-epidemiology (narrow)0.0000.000
Meta-epidemiology (broad)0.0000.000
Bibliometrics0.0000.000
Science and technology studies0.0000.000
Scholarly communication0.0000.000
Open science0.0000.000
Research integrity0.0000.000
Insufficient payload (model declined to judge)0.0000.000

Machine scores (provisional)

The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.

Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.

Opus teacher head0.013
GPT teacher head0.345
Teacher spread0.332 · how far apart the two teachers sit on this one work
Validation statusscore_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from it

Classification

machine, unvalidated

Machine predicted; a candidate call from one teacher head, not a consensus.

The models applied no category: nothing in the taxonomy fit this work.
Study designObservational
Domainnot available
GenreEmpirical

How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".

Quick stats

Citations5
Published2025
Admission routes2
Has abstractyes

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