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Record W4410317969 · doi:10.2196/65853

Mindful Nonreactivity, Anxiety, Depression, and Perceived Stress as Mediators of the Mindfulness Virtual Community Intervention—Pathways to Enhance Mental Health in University Students: Secondary Evaluation of Two Randomized Controlled Trials With Student Participants

2025· article· en· W4410317969 on OpenAlexaffvenue
Meysam Pirbaglou, Christo El Morr, Farah Ahmad, Paul Ritvo

Bibliographic record

VenueJMIR Mental Health · 2025
Typearticle
Languageen
FieldPsychology
TopicMindfulness and Compassion Interventions
Canadian institutionsYork University
Fundersnot available
KeywordsMindfulnessAnxietyMental healthPsychologyClinical psychologyIntervention (counseling)Psychological interventionPsychotherapistPreprintDepression (economics)Psychiatry

Abstract

fetched live from OpenAlex

BACKGROUND: Mindfulness-based interventions (MBIs) are widely employed in mental health promotion and treatment. Despite widespread evidence of effectiveness with different populations and delivery modes, there are sparse findings concerning the mechanisms of action in MBIs. OBJECTIVE: This study, based on a secondary evaluation of two randomized controlled trials (RCTs) with student participants, was aimed at understanding mediators of the Mindfulness Virtual Community (MVC) intervention, an 8-week, multi-component, online mindfulness and cognitive-behavioral therapy (M-CBT) intervention. METHODS: Mediation analysis, using structural equation modeling, was used to assess direct and indirect relationships between study group (i.e. intervention versus wait list control) and outcomes. Consistent with the intervention's theoretical perspective and direct effects paths, a model was specified to evaluate whether mindful non-reactivity, as evaluated by the five-factor mindfulness questionnaire, mediated the effect of study group on anxiety and depression (as symptom-driven outcomes), and perceived stress and quality of life (as functional outcomes). The model included additional mediating paths for perceived stress through anxiety and depression, and for quality of life through anxiety, depression, and perceived stress. The model was thereafter extended, adjusting for pre-intervention differences in mindfulness (i.e. observing, describing, activity with awareness, non-judgement, and non-reactivity) facets. RESULTS: Direct (non-mediated) effects indicated statistically significant differences at 8 weeks between the MVC and waitlist control (WLC) groups on depression (-1.65, P=.003), anxiety (-3.29, P<.001), perceived stress (-2.28, P=.001), and quality of life (4.07, P=.003), and the non-reactivity facet of mindfulness (1.55, P=.001) in favor of the MWC intervention. Mediation analysis supported the mediating role of the non-reactivity facet of mindfulness, depression, anxiety and perceived stress through single and sequential mediation paths. Results indicated good fit characteristics for the main (CFI=.988; RMSEA=.052; SRMR=.045) and extended (CFI=.992; RMSEA=.043; SRMR=.036) models. CONCLUSIONS: This research underscores the importance of mindful non-reactivity, depression, and anxiety as key mediators of MVC intervention benefits.

Fetched live from OpenAlex and de-inverted. Abstracts are not stored in this database: the inverted indexes are 8.6 GB of the frame’s 9.3 GB of text, and the host has 13 GB free.

How this classification was reachedexpand

Full frame machine prediction

Teacher imitation

Not calibrated prevalence, not ground truth. Human validation pending. The Gemma side is a direct model label for every work in the frame, read from the title-only record. The Codex side is a classifier learned from the 10,348 direct Codex labels and calibrated to design-weighted sample rates; fields without enough sample support carry no Codex call. Candidate is the union of the two sides; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels.

metaresearch head score (Codex)0.015
metaresearch head score (Gemma)0.016
Version: metacan-v3-hybrid-931329e0061cValidation status: machine_predicted_unvalidated
Candidate categoriesnone
Consensus categoriesnone
DomainCandidate signal: none · Consensus signal: none
Study designCandidate signal: Observational · Consensus signal: none
GenreCandidate signal: Empirical · Consensus signal: Empirical
Teacher disagreement score0.015
Threshold uncertainty score0.077

Distilled classifier scores by category (both heads)

CategoryCodexGemma
Metaresearch0.0150.016
Meta-epidemiology (narrow)0.0010.001
Meta-epidemiology (broad)0.0040.006
Bibliometrics0.0010.001
Science and technology studies0.0010.001
Scholarly communication0.0020.001
Open science0.0010.001
Research integrity0.0020.002
Insufficient payload (model declined to judge)0.0050.000

Machine scores (provisional)

The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.

Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.

Opus teacher head0.036
GPT teacher head0.436
Teacher spread0.400 · how far apart the two teachers sit on this one work
Validation statusscore_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from it

Classification

machine, unvalidated

Machine predicted; a candidate call from one source (direct Gemma or distilled Codex), not a consensus.

The models applied no category: nothing in the taxonomy fit this work.
Study designObservational
Domainnot available
GenreEmpirical

How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".

Quick stats

Citations0
Published2025
Admission routes2
Has abstractyes

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