12-Month Intraocular Pressure and Hypotensive Medications Outcomes After Phaco-ELIOS Procedure–A Real World Study
Bibliographic record
Abstract
PRÉCIS: Combined phaco-ELIOS in ocular hypertension and glaucoma showed a statistically significant reduction in the number of hypotensive medications of 1.5 compared with baseline, with 78.4% of eyes being medication-free at 12 months. PURPOSE: To describe the change in medication and intraocular pressure 12 months after the combined phacoemulsification-ELIOS procedure. METHODS: Retrospective, multicenter interventional case series of adults with ocular hypertension or glaucoma undergoing phaco-ELIOS. Clinical data were collected and analyzed from preoperative baseline up to 12 months postoperatively. The primary outcome was the mean change in medication compared with baseline. Secondary outcomes were intraocular pressure change from baseline, incidence of acute postoperative intraocular pressure elevation, and surgical success at 1 year, defined as intraocular pressure reduction of ≥20% compared with baseline with no increase in medications, or reduction of ≥1 medications compared with baseline with intraocular pressure equal or below baseline, with no secondary glaucoma surgeries and no loss of light perception. RESULTS: One hundred twelve eyes were included. Forty-two patients (51.2%) were female. Mean (±SD) age was 70.6 (±9.6) years. The most frequent diagnosis was primary open angle glaucoma (71.4%). The mean number of medications at baseline and 12 months was 1.8 (±0.8) and 0.4 (±0.7), respectively, representing a reduction of 1.5 (±1.0) ( P <0.0001). At the end of follow-up, 78.4% of eyes were medication-free. Mean intraocular pressure at baseline and 12 months was 19.9 (±4.0) mm Hg and 16.7 (±2.6) mm Hg, respectively, a significant decrease of 3.2 mm Hg (±4.0) or 13.7% ( P <0.0001). Surgical success was achieved in 75.9% of eyes at 12 months. CONCLUSIONS: Combined phaco-ELIOS in glaucoma significantly reduced medication use and IOP, with over 75% of eyes being medication-free at 12 months.
Fetched live from OpenAlex and de-inverted. Abstracts are not stored in this database: the inverted indexes are 8.6 GB of the frame’s 9.3 GB of text, and the host has 13 GB free.
How this classification was reachedexpand
Full frame distilled prediction
Teacher imitationNot calibrated prevalence, not ground truth. Human validation pending. Learned from the 10,348 direct Codex labels and 10,348 direct Gemma labels. Candidate is the union of thresholded teacher heads; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels or direct frontier model labels.
Codex and Gemma teacher scores by category
| Category | Codex | Gemma |
|---|---|---|
| Metaresearch | 0.000 | 0.000 |
| Meta-epidemiology (narrow) | 0.000 | 0.000 |
| Meta-epidemiology (broad) | 0.001 | 0.000 |
| Bibliometrics | 0.000 | 0.000 |
| Science and technology studies | 0.000 | 0.000 |
| Scholarly communication | 0.000 | 0.000 |
| Open science | 0.000 | 0.000 |
| Research integrity | 0.000 | 0.000 |
| Insufficient payload (model declined to judge) | 0.000 | 0.000 |
Machine scores (provisional)
The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.
Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.
score_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from itClassification
machine, unvalidatedMachine predicted; a candidate call from one teacher head, not a consensus.
How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".