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Record W4410379186 · doi:10.1186/s12888-025-06947-5

Association between living arrangement and psychological well-being among patients with major depressive disorder: the moderating role of body mass index

2025· article· en· W4410379186 on OpenAlexaff
Chengxi Wen, Yifeng Liu, Yanzhi Li, Ruiying Chen, Xiuping He, Xiaojuan Zhang, Yuhua Liao, Jiejing Hao, Yan Chen, Wanxin Wang, Huimin Zhang, Lan Guo, Roger S. McIntyre, Kayla M. Teopiz, Ciyong Lu, Xue Han

Bibliographic record

VenueBMC Psychiatry · 2025
Typearticle
Languageen
FieldSocial Sciences
TopicHealth disparities and outcomes
Canadian institutionsBrain and Cognition Discovery FoundationUniversity of Toronto
FundersSanming Project of Medicine in ShenzhenNational Natural Science Foundation of China
KeywordsBody mass indexAssociation (psychology)Major depressive disorderPsychologyClinical psychologyIndex (typography)Depressive symptomsModerationPsychiatryMedicinePsychotherapistMoodAnxietySocial psychology

Abstract

fetched live from OpenAlex

BACKGROUND: Major depressive disorder (MDD) is highly prevalent globally, significantly impacting psychological well-being (PWB). Herein, we aim to evaluate the impact of different living arrangements on PWB in individuals with MDD and explore the potential moderating role of BMI in this relationship. METHODS: Participants with MDD were recruited from a specialist mental health hospital between December 2019 and April 2023. The diagnosis of MDD was assessed by trained psychiatrists using the Mini-International Neuropsychiatric Interview (M.I.N.I.). Psychological well-being was evaluated using the World Health Organization-Five Well-Being Index. Univariable and multivariable logistic regression models were used to examine the association between different living arrangements and PWB at the 12-month follow-up. The Participants were categorized into underweight, normal weight, and overweight groups based on BMI, followed by conducting stratified analysis. RESULTS: After adjusting for covariates, living with family (AOR = 1.80, 95%CI = 1.14-2.87, P = 0.026) was associated with a higher PWB. There was significant moderating effect of BMI on the association of living arrangements with PWB (P = 0.049). The stratification analyses revealed significant associations between living arrangements and PWB in the normal weight group, while no significant associations were found in the underweight and overweight groups. CONCLUSIONS: Living with family was significantly associated with higher levels of PWB in individuals with MDD, especially among those with a normal BMI. These findings highlight the synergistic effect of living with family and maintaining a healthy BMI on improving PWB in depressed individuals.

Fetched live from OpenAlex and de-inverted. Abstracts are not stored in this database: the inverted indexes are 8.6 GB of the frame’s 9.3 GB of text, and the host has 13 GB free.

How this classification was reachedexpand

Full frame machine prediction

Teacher imitation

Not calibrated prevalence, not ground truth. Human validation pending. The Gemma side is a direct model label for every work in the frame, read from the title-only record. The Codex side is a classifier learned from the 10,348 direct Codex labels and calibrated to design-weighted sample rates; fields without enough sample support carry no Codex call. Candidate is the union of the two sides; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels.

metaresearch head score (Codex)0.001
metaresearch head score (Gemma)0.002
Version: metacan-v3-hybrid-931329e0061cValidation status: machine_predicted_unvalidated
Candidate categoriesnone
Consensus categoriesnone
DomainCandidate signal: none · Consensus signal: none
Study designCandidate signal: Observational · Consensus signal: Observational
GenreCandidate signal: Empirical · Consensus signal: Empirical
Teacher disagreement score0.006
Threshold uncertainty score0.011

Distilled classifier scores by category (both heads)

CategoryCodexGemma
Metaresearch0.0010.002
Meta-epidemiology (narrow)0.0000.000
Meta-epidemiology (broad)0.0000.001
Bibliometrics0.0000.001
Science and technology studies0.0000.000
Scholarly communication0.0010.000
Open science0.0000.001
Research integrity0.0000.001
Insufficient payload (model declined to judge)0.0020.000

Machine scores (provisional)

The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.

Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.

Opus teacher head0.008
GPT teacher head0.283
Teacher spread0.276 · how far apart the two teachers sit on this one work
Validation statusscore_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from it

Classification

machine, unvalidated

Machine predicted; a candidate call from one source (direct Gemma or distilled Codex), not a consensus.

The models applied no category: nothing in the taxonomy fit this work.
Study designObservational
Domainnot available
GenreEmpirical

How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".

Quick stats

Citations1
Published2025
Admission routes1
Has abstractyes

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