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Record W4410395407 · doi:10.1371/journal.pone.0323603

Timing of eye removal influences low-vision quality of life and self-perception of facial appearance in people with one eye

2025· article· en· W4410395407 on OpenAlexafffund
Aysha N. Kinakool, Stefania S. Moro, Jennifer K. E. Steeves

Bibliographic record

VenuePLoS ONE · 2025
Typearticle
Languageen
FieldBiochemistry, Genetics and Molecular Biology
TopicOcular Disorders and Treatments
Canadian institutionsYork University
FundersNatural Sciences and Engineering Research Council of CanadaCanada First Research Excellence FundCanada Foundation for Innovation
KeywordsPsychosocialQuality of life (healthcare)PsychologyAnxietyPerceptionEnucleationBinocular visionDevelopmental psychologyMedicineClinical psychologyPsychiatrySurgeryPsychotherapist

Abstract

fetched live from OpenAlex

PURPOSE: The loss of one eye early compared to late in life coincides with critical periods of postnatal visual development and is associated with sensory adaptations which may lead to different psychosocial experiences throughout life. This study investigates the impact of age at enucleation on psychosocial health factors, namely low-vision quality of life, self-perception of facial appearance, anxiety, and depression. METHODS: Twenty-two participants with early or late eye removal and twenty-seven binocular viewing controls completed the Low-Vision Quality of Life questionnaire, Facial Appearance sub-scale of the Negative Physical Self-Scale and the Hospital Anxiety and Depression scale. RESULTS: Low-vision quality of life was lower for people who had their eye removed late in life compared to binocular viewing controls. Further, within this group, lower self-perception of facial appearance was associated with lower low-vision quality of life. Moreover, experience with binocularity and time since enucleation were not associated with psychosocial health factors. CONCLUSION: Developmental factors rather than experiential factors appear to influence psychosocial health since binocular experience and time since enucleation were not related to any psychosocial factor. These findings suggest that people who have had their eye removed early in life, during the critical periods of visual development may benefit from better psychosocial outcomes.

Fetched live from OpenAlex and de-inverted. Abstracts are not stored in this database: the inverted indexes are 8.6 GB of the frame’s 9.3 GB of text, and the host has 13 GB free.

How this classification was reachedexpand

Full frame distilled prediction

Teacher imitation

Not calibrated prevalence, not ground truth. Human validation pending. Learned from the 10,348 direct Codex labels and 10,348 direct Gemma labels. Candidate is the union of thresholded teacher heads; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels or direct frontier model labels.

metaresearch head score (Codex)0.000
metaresearch head score (Gemma)0.000
Version: codex-gemma-dda1882f352aValidation status: machine_predicted_unvalidated
Candidate categoriesnone
Consensus categoriesnone
DomainCandidate signal: none · Consensus signal: none
Study designCandidate signal: Observational · Consensus signal: Observational
GenreCandidate signal: Empirical · Consensus signal: Empirical
Teacher disagreement score0.352
Threshold uncertainty score0.249

Codex and Gemma teacher scores by category

CategoryCodexGemma
Metaresearch0.0000.000
Meta-epidemiology (narrow)0.0000.000
Meta-epidemiology (broad)0.0000.000
Bibliometrics0.0000.000
Science and technology studies0.0000.000
Scholarly communication0.0000.000
Open science0.0000.000
Research integrity0.0000.000
Insufficient payload (model declined to judge)0.0000.000

Machine scores (provisional)

The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.

Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.

Opus teacher head0.014
GPT teacher head0.269
Teacher spread0.255 · how far apart the two teachers sit on this one work
Validation statusscore_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from it

Classification

machine, unvalidated

Machine predicted; a candidate call from one teacher head, not a consensus.

The models applied no category: nothing in the taxonomy fit this work.
Study designObservational
Domainnot available
GenreEmpirical

How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".

Quick stats

Citations0
Published2025
Admission routes2
Has abstractyes

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