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Record W4410420444 · doi:10.1101/2025.05.16.25327749

Automatic detection of n-degree family members

2025· preprint· en· W4410420444 on OpenAlexaff
Emil M. Pedersen, Jette Steinbach, Carsten Bøcker Pedersen, Andrew J. Schork, Morten Dybdahl Krebs, Bjarni J. Vilhjálmsson, Florian Privé

Bibliographic record

VenuemedRxiv · 2025
Typepreprint
Languageen
FieldComputer Science
TopicFace and Expression Recognition
Canadian institutionsInstitute for Biological Sciences
FundersNovo Nordisk
KeywordsDegree (music)Computer scienceMathematicsPhysicsAcoustics

Abstract

fetched live from OpenAlex

Abstract Summary Research in the familial aggregation of diseases and traits utilise information on probands, and their relevant health information enriched with similar information for their family members of interest. The genealogy is typically generated from trio information in registers and biobanks. However it can be tedious and error prone to identify family members other than first-degree relatives. Here, we present a graph-based approach to effectively identify family members of arbitrary degree of relatedness, as well as the means to attach any desired information to each individual for downstream analysis and a function to efficiently calculate a kinship matrix for the identified family members and convert identified family members from a graph back into trio information. Availability and Implementation The R package where these new functionalities are implemented is available on GitHub ( https://github.com/EmilMiP/LTFHPlus ) and on CRAN ( https://cran.r-project.org/web/packages/LTFHPlus/index.html ).

Fetched live from OpenAlex and de-inverted. Abstracts are not stored in this database: the inverted indexes are 8.6 GB of the frame’s 9.3 GB of text, and the host has 13 GB free.

How this classification was reachedexpand

Full frame distilled prediction

Teacher imitation

Not calibrated prevalence, not ground truth. Human validation pending. Learned from the 10,348 direct Codex labels and 10,348 direct Gemma labels. Candidate is the union of thresholded teacher heads; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels or direct frontier model labels.

metaresearch head score (Codex)0.000
metaresearch head score (Gemma)0.000
Version: codex-gemma-dda1882f352aValidation status: machine_predicted_unvalidated
Candidate categoriesnone
Consensus categoriesnone
DomainCandidate signal: none · Consensus signal: none
Study designCandidate signal: Other design · Consensus signal: none
GenreCandidate signal: Empirical · Consensus signal: Empirical
Teacher disagreement score0.927
Threshold uncertainty score0.623

Codex and Gemma teacher scores by category

CategoryCodexGemma
Metaresearch0.0000.000
Meta-epidemiology (narrow)0.0000.000
Meta-epidemiology (broad)0.0000.000
Bibliometrics0.0000.000
Science and technology studies0.0000.000
Scholarly communication0.0000.000
Open science0.0010.001
Research integrity0.0000.000
Insufficient payload (model declined to judge)0.0000.000

Machine scores (provisional)

The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.

Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.

Opus teacher head0.036
GPT teacher head0.269
Teacher spread0.233 · how far apart the two teachers sit on this one work
Validation statusscore_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from it

Classification

machine, unvalidated

Machine predicted; a candidate call from one teacher head, not a consensus.

The models applied no category: nothing in the taxonomy fit this work.
Study designOther design
Domainnot available
GenreEmpirical

How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".

Quick stats

Citations0
Published2025
Admission routes1
Has abstractyes

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