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Record W4410457866 · doi:10.18295/2075-0528.2839

The Relationship between Female Genital Mutilation and Infertility: <i>A systematic review and meta-analysis</i>

2025· review· en· W4410457866 on OpenAlexaboutno aff
N. Soltani, Farahnaz Heshmat, Mohsen Dehghani, Robab Latifnejad Roudsari, Mohadese B Ghalibaf, Samira Ebrahimzadeh Zagami

Bibliographic record

VenueSultan Qaboos University medical journal · 2025
Typereview
Languageen
FieldMedicine
TopicFemale Genital Mutilation/Cutting Issues
Canadian institutionsnot available
FundersMashhad University of Medical Sciences
KeywordsMedicineMeta-analysisInfertilityGynecologyFemale circumcisionObstetricsSex organSystematic reviewFemale infertilityMEDLINEAndrologyPregnancyInternal medicine

Abstract

fetched live from OpenAlex

This systematic review aimed to investigate the relationship between female genital mutilation (FGM) and infertility. Online databases were systematically searched up to January 2024 using MeSH keywords to retrieve relevant observational studies. The methodological quality of the analytical cross-sectional studies was assessed using the Newcastle–Ottawa Scale. Pooled odds ratios (OR) with 95% confidence intervals (CI) were calculated, and a random-effects meta-analysis was used to address any heterogeneity. Additionally, a sensitivity analysis was performed. A total of 5 analytical cross-sectional studies involving 37,146 participants, with 3 studies meeting the criteria for the meta-analysis. The results indicated that female circumcision (FC) was linked to a 21% increase in the odds of developing infertility compared to non-circumcision, although this finding was not statistically significant (OR = 1.21, 95% CI: 0.98–1.50). Notably, there was no evidence of significant heterogeneity between the studies (P = 0.84 [Q statistics], I2 = 0.0%). While a statistically significant relationship between FGM and infertility was not established, the odds of infertility were higher in the circumcised group. Consequently, it is imperative to prioritise efforts to eradicate FC, especially among young girls.

Fetched live from OpenAlex and de-inverted. Abstracts are not stored in this database: the inverted indexes are 8.6 GB of the frame’s 9.3 GB of text, and the host has 13 GB free.

How this classification was reachedexpand

Full frame machine prediction

Teacher imitation

Not calibrated prevalence, not ground truth. Human validation pending. The Gemma side is a direct model label for every work in the frame, read from the title-only record. The Codex side is a classifier learned from the 10,348 direct Codex labels and calibrated to design-weighted sample rates; fields without enough sample support carry no Codex call. Candidate is the union of the two sides; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels.

metaresearch head score (Codex)0.011
metaresearch head score (Gemma)0.036
Version: metacan-v3-hybrid-931329e0061cValidation status: machine_predicted_unvalidated
Candidate categoriesnone
Consensus categoriesnone
DomainCandidate signal: none · Consensus signal: none
Study designCandidate signal: Meta-analysis · Consensus signal: none
GenreCandidate signal: Review · Consensus signal: Review
Teacher disagreement score0.011
Threshold uncertainty score0.060

Distilled classifier scores by category (both heads)

CategoryCodexGemma
Metaresearch0.0110.036
Meta-epidemiology (narrow)0.0020.001
Meta-epidemiology (broad)0.0110.019
Bibliometrics0.0090.008
Science and technology studies0.0010.001
Scholarly communication0.0030.002
Open science0.0010.001
Research integrity0.0020.002
Insufficient payload (model declined to judge)0.0040.000

Machine scores (provisional)

The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.

Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.

Opus teacher head0.080
GPT teacher head0.338
Teacher spread0.258 · how far apart the two teachers sit on this one work
Validation statusscore_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from it

Classification

machine, unvalidated

Machine predicted; a candidate call from one source (direct Gemma or distilled Codex), not a consensus.

The models applied no category: nothing in the taxonomy fit this work.
Study designMeta-analysis
Domainnot available
GenreReview

How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".

Quick stats

Citations0
Published2025
Admission routes1
Has abstractyes

Explore more

Same venueSultan Qaboos University medical journalSame topicFemale Genital Mutilation/Cutting IssuesFrench-language works237,207