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Record W4410474988 · doi:10.1093/gerona/glaf111

Foundations and Strategic Vision of the Canadian Translational Geroscience Network

2025· article· en· W4410474988 on OpenAlexafffundabout
Guy Hajj‐Boutros, Andréa Faust, John Muscedere, Perry Kim, Gilles Gouspillou, Lea Harrington, James L. Kirkland, George A. Kuchel, Jeremy M. Van Raamsdonk, R. Jane Rylett, Chantal Autexier, Louis R. Lapierre, Michael S. Kobor, Mohammad Auais, Ann Beliën, Jeroen Aerssens, George L. Sutphin, Kenneth Rockwood, Αλεξάνδρα Παπαϊωάννου, Marc Sim, Jamie N. Justice, Nancy E. Mayo, Gustavo Duque

Bibliographic record

VenueThe Journals of Gerontology Series A · 2025
Typearticle
Languageen
FieldMedicine
TopicFrailty in Older Adults
Canadian institutionsUniversity of British ColumbiaUniversité de MonctonMcGill UniversityWestern UniversityDalhousie UniversityUniversity of TorontoMcMaster UniversityUniversité du Québec à MontréalQueen's UniversityCanadian Respiratory Research NetworkMcGill University Health Centre
FundersNational Institute on AgingCanadian Frailty NetworkMcGill University
KeywordsMilestoneExcellenceTransformative learningTranslational researchHealth carePopulation ageingMultidisciplinary approachPolitical sciencePopulation healthPsychological interventionPublic relationsBest practiceGerontologyLibrary sciencePopulationMedicineSociologyNursing

Abstract

fetched live from OpenAlex

Geroscience is an emerging interdisciplinary field that explores the biological connections between aging and the development of chronic diseases, with the ultimate goal of identifying interventions to extend healthspan and delay age-related conditions. Recognizing the growing importance of this field, the Canadian Translational Geroscience Network (geroscience.ca) was officially launched during a conference held in Montreal on September 5-6, 2024. Building on the momentum of successful Geroscience meetings in Toronto and Montreal in 2023, this milestone event marked a transformative step forward for geroscience in Canada. This event brought together key stakeholders, including the Canadian Frailty Network (CFN), the Canadian Institutes of Health Research Institute of Aging (CIHR-IA), the Réseau Québécois de Recherche sur le Vieillissement (RQRV), the Simone & Edouard Schouela RUISSS McGill Centre of Excellence for Sustainable Health of Seniors (Schouela CEDurable), the Division of Geriatric Medicine at McGill University, and the Department of Biochemistry at the University of Toronto. Additionally, a broad coalition of geriatricians, healthcare professionals, and researchers convened to discuss and advance the field of geroscience in Canada. The 2-day conference focused on creating a multidisciplinary community to address the challenges of an aging population, emphasizing the importance of funding, national and international collaboration, and training the next generation of researchers and clinicians. Workshops and presentations showcased a range of innovative research, from cellular studies to clinical trials, aimed at understanding and treating age-related diseases. Key discussions highlighted the critical role of partnerships among research institutions, healthcare systems, and biotech companies in translating research findings into practical interventions. The Canadian Translational Geroscience Network's strategic objectives focus on expanding funding opportunities for geroscience, developing specialized training programs, and increasing membership to cultivate a diverse, multidisciplinary, and collaborative network. This network aims to include students, basic and clinical researchers, citizens, government entities, and organizations or professionals interested in advancing the geroscience field. With a clear roadmap for future growth, the Canadian Translational Geroscience Network aims to position Canada at the forefront of geroscience, fostering evidence-based innovation that improves the health and quality of life for aging populations.

Fetched live from OpenAlex and de-inverted. Abstracts are not stored in this database: the inverted indexes are 8.6 GB of the frame’s 9.3 GB of text, and the host has 13 GB free.

How this classification was reachedexpand

Full frame machine prediction

Teacher imitation

Not calibrated prevalence, not ground truth. Human validation pending. The Gemma side is a direct model label for every work in the frame, read from the title-only record. The Codex side is a classifier learned from the 10,348 direct Codex labels and calibrated to design-weighted sample rates; fields without enough sample support carry no Codex call. Candidate is the union of the two sides; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels.

metaresearch head score (Codex)0.045
metaresearch head score (Gemma)0.046
Version: metacan-v3-hybrid-931329e0061cValidation status: machine_predicted_unvalidated
Candidate categoriesnone
Consensus categoriesnone
DomainCandidate signal: none · Consensus signal: none
Study designCandidate signal: Not applicable · Consensus signal: Not applicable
GenreCandidate signal: Empirical · Consensus signal: none
Teacher disagreement score0.842
Threshold uncertainty score0.976

Distilled classifier scores by category (both heads)

CategoryCodexGemma
Metaresearch0.0450.046
Meta-epidemiology (narrow)0.0020.001
Meta-epidemiology (broad)0.0010.001
Bibliometrics0.0050.004
Science and technology studies0.0250.015
Scholarly communication0.0230.008
Open science0.0080.021
Research integrity0.0140.019
Insufficient payload (model declined to judge)0.0170.004

Machine scores (provisional)

The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.

Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.

Opus teacher head0.055
GPT teacher head0.349
Teacher spread0.294 · how far apart the two teachers sit on this one work
Validation statusscore_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from it

Classification

machine, unvalidated

Machine predicted; a candidate call from one source (direct Gemma or distilled Codex), not a consensus.

The models applied no category: nothing in the taxonomy fit this work.
Study designNot applicable
Domainnot available
GenreEmpirical

How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".

Quick stats

Citations0
Published2025
Admission routes3
Has abstractyes

Explore more

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