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Record W4410491427 · doi:10.1021/acsestwater.4c01043

Canary in the Coal Mine: Two-Year Wastewater Surveillance Results from an Indicator Community for Early Indication of IAV, RSV, Mpox, and SARS-CoV-2 in Five Surrounding Towns and Cities

2025· article· en· W4410491427 on OpenAlex
Lena Carolin Bitter, Richard Kibbee, Timothy M. Garant, Banu Örmeci

Why this work is in the frame

A frame that forgets how it found something cannot be audited. These are the routes that admitted this work.

affAt least one author lists a Canadian institution in the pinned OpenAlex snapshot.
fundA Canadian funder is recorded on the work.

Bibliographic record

VenueACS ES&T Water · 2025
Typearticle
Languageen
FieldMedicine
TopicSARS-CoV-2 detection and testing
Canadian institutionsCarleton University
FundersMinistère de l’Environnement, de la Protection de la nature et des Parcs
KeywordsGeographyCoal miningWastewaterEnvironmental healthVeterinary medicineSocioeconomicsCoalArchaeologyMedicineEnvironmental scienceEnvironmental engineeringSociology

Abstract

fetched live from OpenAlex

An indicator community (IC) is a community in a larger population where pathogens can be observed earlier due to its unique characteristics, similar to the canary in the coal mine analogy. This study investigated using a strategically selected IC as an early viral indicator for the City itself and five surrounding towns and cities. Wastewater surveillance was carried out at least three times per week for 2 years to track IAV, RSV, mpox, and SARS-CoV-2. The IC, a university campus, was selected based on its closed-loop sewer system, population demographics, and high social connectivity. Results showed that wastewater surveillance at a well-selected IC can serve as an early indicator of emerging and seasonal viruses, providing a necessary lead time of at least 1 week for timely public health interventions. While wastewater treatment plants typically offer 1–3 days of early detection, the IC approach extended this window to 1–3 weeks. The IC approach was particularly useful as an early indicator of new surges and outbreaks of seasonal respiratory viruses. The results also showed a consistent presence of SARS-CoV-2 wastewater viral signal in all communities, unlike the seasonal respiratory viruses, indicating an ongoing low-level transmission and circulation of SARS-CoV-2 throughout the year.

Fetched live from OpenAlex and de-inverted. Abstracts are not stored in this database: the inverted indexes are 8.6 GB of the frame’s 9.3 GB of text, and the host has 13 GB free.

Full frame distilled prediction

Teacher imitation

Not calibrated prevalence, not ground truth. Human validation pending. Learned from the 10,348 direct Codex labels and 10,348 direct Gemma labels. Candidate is the union of thresholded teacher heads; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels or direct frontier model labels.

metaresearch head score (Codex)0.001
metaresearch head score (Gemma)0.000
Version: codex-gemma-dda1882f352aValidation status: machine_predicted_unvalidated
Candidate categoriesnone
Consensus categoriesnone
DomainCandidate signal: none · Consensus signal: none
Study designCandidate signal: Observational · Consensus signal: Observational
GenreCandidate signal: Empirical · Consensus signal: Empirical
Teacher disagreement score0.213
Threshold uncertainty score0.978

Codex and Gemma teacher scores by category

CategoryCodexGemma
Metaresearch0.0010.000
Meta-epidemiology (narrow)0.0000.000
Meta-epidemiology (broad)0.0000.000
Bibliometrics0.0000.000
Science and technology studies0.0000.000
Scholarly communication0.0000.000
Open science0.0000.000
Research integrity0.0000.000
Insufficient payload (model declined to judge)0.0000.000

Machine scores (provisional)

The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.

Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.

Opus teacher head0.039
GPT teacher head0.314
Teacher spread0.276 · how far apart the two teachers sit on this one work
Validation statusscore_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from it