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Record W4410501991 · doi:10.1093/sleep/zsaf090.1090

1090 Routine Screening for Excessive Daytime Sleepiness in Pediatric Brain Tumor

2025· article· en· W4410501991 on OpenAlexfundno aff
Kayla LaRosa, Keerthi Narasimhan, Valerie McLaughlin Crabtree, Emily Singer, Mustafa Barbour, Lauren Hayes

Bibliographic record

VenueSLEEP · 2025
Typearticle
Languageen
FieldMedicine
TopicChildhood Cancer Survivors' Quality of Life
Canadian institutionsnot available
FundersSocial Sciences and Humanities Research Council of Canada
KeywordsExcessive daytime sleepinessDaytimeMedicinePsychiatrySleep disorderInsomnia

Abstract

fetched live from OpenAlex

Abstract Introduction Youth with brain tumor may experience excessive daytime sleepiness (EDS) associated with central disorders of hypersomnolence (CDH).1 EDS impairs daily functioning, negatively affects mood and quality of life, and further exacerbates cognitive and academic difficulties associated with brain tumor.2 The aim of this study is to summarize findings from universal screening of these issues in pediatric brain tumor. Methods Youth receiving treatment or surveillance for pediatric brain tumor presenting to inpatient or outpatient settings were screened for symptoms of EDS using the Modified Epworth Sleepiness Scale (M-ESS) and the Pediatric Hypersomnolence Survey (PHS). A cut off score of 6 was utilized on the M-ESS.3 The PHS has not yet been used in pediatric cancer, therefore, it was trialed to determine level of agreement with other screening methods. The standard cut off score of 24 or 8 on the sleepiness subscale score was used. Elevated ratings were discussed with the primary oncologist, and a referral was made to Sleep Medicine if deemed necessary. Results Eighteen youth with brain tumor completed screening for sleep problems (61% Low Grade Astrocytoma, 83.3% White). A total of 38.9% (n=7) scored above the cut off on the M-ESS, indicating concern for EDS. On the PHS, a total of 16.6% (n = 3) scored above the cut off for Total score and the Sleepiness subscale, indicating concern for narcolepsy or hypersomnia. Three (16.6%) participants were referred to Sleep Medicine for further evaluation and three others (16.6%) were already established with Sleep Medicine at the time of screening. Conclusion EDS and CDH may be common in pediatric brain tumor.1,2 Screening measures led to increased referral to Sleep Medicine. Despite this, due to discrepancy between measures, further research is needed to determine the best screening methods to accurately determine the presence of EDS in pediatric brain tumor. Support (if any) This study is supported by the Kentucky Pediatric Cancer Research Trust Fund.

Fetched live from OpenAlex and de-inverted. Abstracts are not stored in this database: the inverted indexes are 8.6 GB of the frame’s 9.3 GB of text, and the host has 13 GB free.

How this classification was reachedexpand

Full frame machine prediction

Teacher imitation

Not calibrated prevalence, not ground truth. Human validation pending. The Gemma side is a direct model label for every work in the frame, read from the title-only record. The Codex side is a classifier learned from the 10,348 direct Codex labels and calibrated to design-weighted sample rates; fields without enough sample support carry no Codex call. Candidate is the union of the two sides; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels.

metaresearch head score (Codex)0.001
metaresearch head score (Gemma)0.002
Version: metacan-v3-hybrid-931329e0061cValidation status: machine_predicted_unvalidated
Candidate categoriesnone
Consensus categoriesnone
DomainCandidate signal: none · Consensus signal: none
Study designCandidate signal: Observational · Consensus signal: Observational
GenreCandidate signal: Empirical · Consensus signal: Empirical
Teacher disagreement score0.007
Threshold uncertainty score0.014

Distilled classifier scores by category (both heads)

CategoryCodexGemma
Metaresearch0.0010.002
Meta-epidemiology (narrow)0.0000.000
Meta-epidemiology (broad)0.0000.000
Bibliometrics0.0010.001
Science and technology studies0.0000.000
Scholarly communication0.0000.000
Open science0.0000.000
Research integrity0.0000.000
Insufficient payload (model declined to judge)0.0010.000

Machine scores (provisional)

The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.

Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.

Opus teacher head0.021
GPT teacher head0.328
Teacher spread0.306 · how far apart the two teachers sit on this one work
Validation statusscore_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from it

Classification

machine, unvalidated

Machine predicted; a candidate call from one source (direct Gemma or distilled Codex), not a consensus.

The models applied no category: nothing in the taxonomy fit this work.
Study designObservational
Domainnot available
GenreEmpirical

How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".

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Citations0
Published2025
Admission routes1
Has abstractyes

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