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CHOROIDOPATHY OF SYSTEMIC LUPUS ERYTHEMATOSUS, ABOUT 2 CASES RECEIVED AT THE BRAZZAVILLE OPHTHALMOLOGICAL CENTER

2025· article· en· W4410512998 on OpenAlexvenueno aff
Andre Diandomba, Dieudonne Bimwala

Bibliographic record

VenueThe Journal of Rheumatology · 2025
Typearticle
Languageen
FieldMedicine
TopicSystemic Lupus Erythematosus Research
Canadian institutionsnot available
Fundersnot available
KeywordsMedicineDermatologySystemic diseaseCenter (category theory)Lupus erythematosusImmunopathologyPathologyImmunology

Abstract

fetched live from OpenAlex

PV206 / #35 Poster Topic: AS23 - SLE-Diagnosis, Manifestations, & Outcomes Background/Purpose Lupus choroidopathy is a rare but potentially serious ocular complication of systemic lupus erythematosus (SLE), an autoimmune disease affecting multiple organs and systems. Although choroidopathy is less common than other ocular manifestations of SLE, it can cause significant visual loss if not diagnosed and treated promptly. The objective of this study is to describe 2 cases of lupus choroidopathy treated at the Ophthalmological Center of Brazzaville, in order to illustrate the clinical characteristics, treatment modalities and results obtained. Methods This study is based on the analysis of 2 clinical cases of patients diagnosed with choroidopathy associated with SLE, received at the Ophthalmological Center of Brazzaville. Clinical data were collected from medical records, including medical history, presenting symptoms, results of ophthalmological examinations (ophthalmoscopy, optical coherence tomography (OCT), fluorescein angiography), as well as treatments administered. The patients were followed over a specific period to assess the effectiveness of the treatment and the evolution of their condition. Results Both patients presented a decrease in visual acuity accompanied by scotomas, serous retinal detachments and subretinal exudates, confirmed by ophthalmological examinations. The patients were treated with systemic corticosteroid therapy combined with immunosuppressants, which led to a significant improvement in ocular condition and stabilization of visual function. The clinical course of both cases demonstrated a favorable response to treatment, with a reduction in retinal detachments and inflammatory signs Conclusions Lupus choroidopathy, although rare, should be considered in any patient with systemic lupus erythematosus presenting with visual symptoms. These 2 cases illustrate the importance of early diagnosis and adequate therapeutic management to improve visual outcomes and prevent serious complications. A multidisciplinary approach is crucial for the effective management of this pathology and to minimize the risk of irreversible visual loss in patients with SLE.

Fetched live from OpenAlex and de-inverted. Abstracts are not stored in this database: the inverted indexes are 8.6 GB of the frame’s 9.3 GB of text, and the host has 13 GB free.

How this classification was reachedexpand

Full frame machine prediction

Teacher imitation

Not calibrated prevalence, not ground truth. Human validation pending. The Gemma side is a direct model label for every work in the frame, read from the title-only record. The Codex side is a classifier learned from the 10,348 direct Codex labels and calibrated to design-weighted sample rates; fields without enough sample support carry no Codex call. Candidate is the union of the two sides; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels.

metaresearch head score (Codex)0.000
metaresearch head score (Gemma)0.001
Version: metacan-v3-hybrid-931329e0061cValidation status: machine_predicted_unvalidated
Candidate categoriesnone
Consensus categoriesnone
DomainCandidate signal: none · Consensus signal: none
Study designCandidate signal: Case report · Consensus signal: none
GenreCandidate signal: Empirical · Consensus signal: Empirical
Teacher disagreement score0.006
Threshold uncertainty score0.011

Distilled classifier scores by category (both heads)

CategoryCodexGemma
Metaresearch0.0000.001
Meta-epidemiology (narrow)0.0010.000
Meta-epidemiology (broad)0.0000.000
Bibliometrics0.0010.001
Science and technology studies0.0010.001
Scholarly communication0.0010.001
Open science0.0000.001
Research integrity0.0010.001
Insufficient payload (model declined to judge)0.0030.000

Machine scores (provisional)

The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.

Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.

Opus teacher head0.024
GPT teacher head0.311
Teacher spread0.287 · how far apart the two teachers sit on this one work
Validation statusscore_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from it

Classification

machine, unvalidated

Machine predicted; a candidate call from one source (direct Gemma or distilled Codex), not a consensus.

The models applied no category: nothing in the taxonomy fit this work.
Study designCase report
Domainnot available
GenreEmpirical

How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".

Quick stats

Citations0
Published2025
Admission routes1
Has abstractyes

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