MétaCan
Menu
Back to cohort
Record W4410539343 · doi:10.1093/database/baaf008

An exploratory study combining Virtual Reality and Semantic Web for life science research using Graph2VR

2025· article· en· W4410539343 on OpenAlexaboutno aff
Alexander Kellmann, Sander van den Hoek, Max Postema, W Maassen, Brenda S. Hijmans, Marije A. van der Geest, K. Joeri van der Velde, David van Enckevort, Morris A. Swertz

Bibliographic record

VenueDatabase · 2025
Typearticle
Languageen
FieldBiochemistry, Genetics and Molecular Biology
TopicBiomedical Text Mining and Ontologies
Canadian institutionsnot available
FundersH2020 Health
KeywordsComputer scienceVirtual realityWorld Wide WebExploratory researchSemantic WebInformation retrievalWeb of scienceSocial Semantic WebData scienceHuman–computer interactionMEDLINESociology

Abstract

fetched live from OpenAlex

We previously described Graph2VR, a prototype that enables researchers to use virtual reality (VR) to explore and navigate through Linked Data graphs using SPARQL queries (see https://doi.org/10.1093/database/baae008). Here we evaluate the use of Graph2VR in three realistic life science use cases. The first use case visualizes metadata from large-scale multi-center cohort studies across Europe and Canada via the EUCAN Connect catalogue. The second use case involves a set of genomic data from synthetic rare disease patients, which was processed through the Variant Interpretation Pipeline and then converted into Resource Description Format for visualization. The third use case involves enriching a graph with additional information, in this case, the Dutch Anatomical Therapeutic Chemical code Ontology with the DrugID from Drugbank. These examples collectively showcase Graph2VR's potential for data exploration and enrichment, as well as some of its limitations. We conclude that the endless three-dimensional space provided by VR indeed shows much potential for the navigation of very large knowledge graphs, and we provide recommendations for data preparation and VR tooling moving forward. Database URL: https://doi.org/10.1093/database/baaf008.

Fetched live from OpenAlex and de-inverted. Abstracts are not stored in this database: the inverted indexes are 8.6 GB of the frame’s 9.3 GB of text, and the host has 13 GB free.

How this classification was reachedexpand

Full frame machine prediction

Teacher imitation

Not calibrated prevalence, not ground truth. Human validation pending. The Gemma side is a direct model label for every work in the frame, read from the title-only record. The Codex side is a classifier learned from the 10,348 direct Codex labels and calibrated to design-weighted sample rates; fields without enough sample support carry no Codex call. Candidate is the union of the two sides; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels.

metaresearch head score (Codex)0.010
metaresearch head score (Gemma)0.022
Version: metacan-v3-hybrid-931329e0061cValidation status: machine_predicted_unvalidated
Candidate categoriesnone
Consensus categoriesnone
DomainCandidate signal: none · Consensus signal: none
Study designCandidate signal: Bench or experimental · Consensus signal: none
GenreCandidate signal: Empirical · Consensus signal: Empirical
Teacher disagreement score0.010
Threshold uncertainty score0.051

Distilled classifier scores by category (both heads)

CategoryCodexGemma
Metaresearch0.0100.022
Meta-epidemiology (narrow)0.0010.000
Meta-epidemiology (broad)0.0000.001
Bibliometrics0.0040.004
Science and technology studies0.0010.001
Scholarly communication0.0040.004
Open science0.0020.004
Research integrity0.0010.001
Insufficient payload (model declined to judge)0.0060.001

Machine scores (provisional)

The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.

Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.

Opus teacher head0.142
GPT teacher head0.447
Teacher spread0.305 · how far apart the two teachers sit on this one work
Validation statusscore_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from it

Classification

machine, unvalidated

Machine predicted; a candidate call from one source (direct Gemma or distilled Codex), not a consensus.

The models applied no category: nothing in the taxonomy fit this work.
Study designBench or experimental
Domainnot available
GenreEmpirical

How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".

Quick stats

Citations0
Published2025
Admission routes1
Has abstractyes

Explore more

Same venueDatabaseSame topicBiomedical Text Mining and OntologiesFrench-language works237,207