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METABOLIC IMPACT OF SOCIAL TRANSITIONS IN CANADA: A PROSPECTIVE STUDY OF AGING WOMEN AND MEN IN THE CANADIAN LONGITUDINAL STUDY ON AGING (2011-2021)

2025· article· en· W4410587594 on OpenAlexaffabout
Annalijn Conklin, Rana Madani Civi, Gilciane Ceolin, Sanaz Mehranfar, Gerry Veenstra, Nadia Khan

Bibliographic record

VenueJournal of Hypertension · 2025
Typearticle
Languageen
FieldMedicine
TopicLiver Disease Diagnosis and Treatment
Canadian institutionsUniversity of British Columbia
Fundersnot available
KeywordsMedicineGerontologyProspective cohort studyLongitudinal studyDemographyInternal medicinePathology

Abstract

fetched live from OpenAlex

Objective: We aimed to prospectively examine alterations in different social connections and change in waist circumference (WC) among aging Canadians, by gender Design and method: A population-based prospective study of middle-age and older adults in the Canadian Longitudinal Study on Aging (CLSA, 2011-2021) assessed change in marital status, living arrangements, and social participation (waves 1 to 2) and change in waist circumference (WC) at wave 3 (adjusted for wave 2). Stratified, multivariable mixed regression, and predicted means (95% CI), estimated effects by (cis-)gender adjusting for 9 individual and 3 provincial covariables. Sample sizes varied: 13,941 participants for marital and living arrangement transitions and 13,921 for changes in social participation. Results: Overall, mean WC declined over the 6-year follow-up time. We found that alterations in different social connections were associated with subsequent WC changed in a gendered pattern. Among women, only decreased social participation was significantly associated with subsequent change in WC among women (+0.47 cm [0.11, 0.83]) compared to women with stable social participation; although increased social participation also signaled less decline in WC (+0.32 cm [-0.04, 0.68]). Among men, only becoming divorced was significantly associated with subsequent changes in WC (+1.45 cm [0.14, 2.75]), compared to remaining partnered; notably, men becoming widowed had a similar magnitude but a non-significant inverse association (-1.41 [-2.85, 0.03]). Results for changes in living arrangement and subsequent change in WC were null but directions differed by gender. Predicted mean WC at 6-year follow-up were seen for uncertain marital transitions among women (87.95 cm [86.95, 88.94]) and for becoming divorced among men (100.54 cm [99.17,101.91]), placing both in the ‘high risk’ category for diabetes and coronary heart disease. Results were robust to alternative model specification and to further adjustment of all baseline social ties. Conclusions: This study revealed unique gender-specific patterns of change in social connections linked to WC change. Decreased social participation increased mean WC among women, whereas becoming divorced increased WC among men in Canada. Findings underscore the importance of disaggregated data and the unique role of specific changes in social connections for future risk of cardiovascular disease.

Fetched live from OpenAlex and de-inverted. Abstracts are not stored in this database: the inverted indexes are 8.6 GB of the frame’s 9.3 GB of text, and the host has 13 GB free.

How this classification was reachedexpand

Full frame machine prediction

Teacher imitation

Not calibrated prevalence, not ground truth. Human validation pending. The Gemma side is a direct model label for every work in the frame, read from the title-only record. The Codex side is a classifier learned from the 10,348 direct Codex labels and calibrated to design-weighted sample rates; fields without enough sample support carry no Codex call. Candidate is the union of the two sides; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels.

metaresearch head score (Codex)0.001
metaresearch head score (Gemma)0.001
Version: metacan-v3-hybrid-931329e0061cValidation status: machine_predicted_unvalidated
Candidate categoriesnone
Consensus categoriesnone
DomainCandidate signal: none · Consensus signal: none
Study designCandidate signal: Observational · Consensus signal: Observational
GenreCandidate signal: Empirical · Consensus signal: Empirical
Teacher disagreement score0.017
Threshold uncertainty score0.121

Distilled classifier scores by category (both heads)

CategoryCodexGemma
Metaresearch0.0010.001
Meta-epidemiology (narrow)0.0010.000
Meta-epidemiology (broad)0.0010.001
Bibliometrics0.0010.004
Science and technology studies0.0040.000
Scholarly communication0.0010.000
Open science0.0010.001
Research integrity0.0010.001
Insufficient payload (model declined to judge)0.0010.000

Machine scores (provisional)

The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.

Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.

Opus teacher head0.032
GPT teacher head0.299
Teacher spread0.267 · how far apart the two teachers sit on this one work
Validation statusscore_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from it

Classification

machine, unvalidated

Machine predicted; a candidate call from one source (direct Gemma or distilled Codex), not a consensus.

The models applied no category: nothing in the taxonomy fit this work.
Study designObservational
Domainnot available
GenreEmpirical

How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".

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Citations0
Published2025
Admission routes2
Has abstractyes

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