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Record W4410594902 · doi:10.1080/21645515.2025.2506286

Coverage disparities and delayed immunization: Assessing 12-month vaccination completion in Canadian children using data from a digital immunization platform

2025· article· en· W4410594902 on OpenAlexafffundabout
Mohamed Serhan, Adhiba Nilormi, Blaise Ntacyabukura, Katherine Atkinson, Robin Ducharme, Steven Hawken, Tim Ramsay, Joyce Ang, Kumanan Wilson

Bibliographic record

VenueHuman Vaccines & Immunotherapeutics · 2025
Typearticle
Languageen
FieldSocial Sciences
TopicVaccine Coverage and Hesitancy
Canadian institutionsUniversity of OttawaBruyèreUniversity of British ColumbiaOttawa Hospital
FundersPfizer CanadaPfizer
KeywordsImmunizationVaccinationMedicinePediatricsImmunologyAntibody

Abstract

fetched live from OpenAlex

On-time vaccination is essential for community protection against vaccine-preventable diseases. Insufficient on-time coverage and immunization series completion can put the population at risk. This study described individual coverage and series completion rates of the 12-month dose of pneumococcal, meningococcal, and measles-mumps-rubella (MMR) vaccines, as well as predictors of these rates in Canada. We conducted a cross-sectional study with immunization data from the pan-Canadian digital vaccination tool (CANImmunize) to evaluate coverage of the 12-month dose for single and multiple-dose vaccines. We conducted bivariate and multivariate logistic regression analyses to investigate associations between factors such as account holder gender, active integration of vaccine record with a public health unit (PHU) and inclusion of linked records in CANImmunize, with vaccination coverage. We calculated crude and adjusted odds ratios and 95% confidence intervals. We analyzed 60,890 records from children aged 13 months to 18 years. Coverage of the 12-month's dose of multiple-dose vaccines was significantly lower compared to single-dose vaccines. 14.28% versus 17.23% of children who had reported the first dose of pneumococcal and meningococcal vaccines, respectively, have not received the 12-month dose of the same vaccine. Additionally, 10-13.2% of children who received the 12-month dose of pneumococcal, meningococcal, and MMR vaccines received the vaccine late (13+ months). Based on our data, there is a gap in the coverage of the 12-month dose between single and multiple-dose vaccines, and the 12-month dose was delayed for a proportion of children. Reminder interventions targeting populations with identified predictors of sub-optimal coverage may be valuable.

Fetched live from OpenAlex and de-inverted. Abstracts are not stored in this database: the inverted indexes are 8.6 GB of the frame’s 9.3 GB of text, and the host has 13 GB free.

How this classification was reachedexpand

Full frame machine prediction

Teacher imitation

Not calibrated prevalence, not ground truth. Human validation pending. The Gemma side is a direct model label for every work in the frame, read from the title-only record. The Codex side is a classifier learned from the 10,348 direct Codex labels and calibrated to design-weighted sample rates; fields without enough sample support carry no Codex call. Candidate is the union of the two sides; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels.

metaresearch head score (Codex)0.003
metaresearch head score (Gemma)0.011
Version: metacan-v3-hybrid-931329e0061cValidation status: machine_predicted_unvalidated
Candidate categoriesnone
Consensus categoriesnone
DomainCandidate signal: none · Consensus signal: none
Study designCandidate signal: Observational · Consensus signal: Observational
GenreCandidate signal: Empirical · Consensus signal: Empirical
Teacher disagreement score0.016
Threshold uncertainty score0.115

Distilled classifier scores by category (both heads)

CategoryCodexGemma
Metaresearch0.0030.011
Meta-epidemiology (narrow)0.0000.000
Meta-epidemiology (broad)0.0000.001
Bibliometrics0.0030.008
Science and technology studies0.0010.001
Scholarly communication0.0010.001
Open science0.0010.001
Research integrity0.0000.001
Insufficient payload (model declined to judge)0.0010.000

Machine scores (provisional)

The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.

Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.

Opus teacher head0.056
GPT teacher head0.340
Teacher spread0.283 · how far apart the two teachers sit on this one work
Validation statusscore_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from it

Classification

machine, unvalidated

Machine predicted; a candidate call from one source (direct Gemma or distilled Codex), not a consensus.

The models applied no category: nothing in the taxonomy fit this work.
Study designObservational
Domainnot available
GenreEmpirical

How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".

Quick stats

Citations1
Published2025
Admission routes3
Has abstractyes

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