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Record W4410634476 · doi:10.1002/mdc3.70132

Disparities in the Clinical Provision of Deep Brain Stimulation: A Systematic Scoping Review and Grounded‐Theory Qualitative Analysis

2025· article· en· W4410634476 on OpenAlexaff
Wellington Chang, Talia Ganz, Sara Kang, Kacey Hu, Catherine Mark, Adam C. Frank, Brian Lee, Darrin Jason Lee, R. Bernard Coley, Rachel Carmen Ceasar, Xenos Mason

Bibliographic record

VenueMovement Disorders Clinical Practice · 2025
Typearticle
Languageen
FieldMedicine
TopicNeurological disorders and treatments
Canadian institutionsYork University
FundersNational Center for Advancing Translational Sciences
KeywordsGrounded theoryHealth equityQualitative researchDisadvantagedSocioeconomic statusDeep brain stimulationEquity (law)MedicinePsychologyApplied psychologyPolitical scienceSociologyNursingPopulationSocial sciencePublic health

Abstract

fetched live from OpenAlex

BACKGROUND: Deep Brain Stimulation (DBS) has been an established treatment for movement disorders since its FDA approval in 1996. However, disparities in DBS care, particularly concerning race, gender, socioeconomic status, and geography, remain a significant concern globally. OBJECTIVES: This systematic scoping review and grounded theory qualitative analysis aimed to synthesize existing research on worldwide disparities in DBS provision and to develop theoretical solutions to enhance equity and improve the quality of research in DBS disparities. METHODS: A systematic search identified 46 studies, which were critically appraised for quality and analyzed using grounded theory methods to extract core conceptual categories. RESULTS: We characterized three principles of DBS disparities: intersectionality, reciprocal interactivity and influence of patients and providers, and the interposition of simultaneous barriers; together these highlight the role of individual, systemic, and structural factors in generating DBS disparities. Racial minorities, women, socioeconomically disadvantaged individuals, and patients in certain geographic regions were consistently found to have reduced access to DBS. Gaps in the research include a calcified research infrastructure, insufficient attention to cultural and societal contexts, and reliance on conjecture without empirical support. CONCLUSIONS: We propose a multi-level approach to address DBS disparities, including reciprocal education between patients and clinicians, enhanced screening and referral networks, and policy reforms at institutional and governmental levels. These findings will facilitate further hypothesis-driven research and foster more equitable access to DBS globally.

Fetched live from OpenAlex and de-inverted. Abstracts are not stored in this database: the inverted indexes are 8.6 GB of the frame’s 9.3 GB of text, and the host has 13 GB free.

How this classification was reachedexpand

Full frame distilled prediction

Teacher imitation

Not calibrated prevalence, not ground truth. Human validation pending. Learned from the 10,348 direct Codex labels and 10,348 direct Gemma labels. Candidate is the union of thresholded teacher heads; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels or direct frontier model labels.

metaresearch head score (Codex)0.010
metaresearch head score (Gemma)0.027
Version: codex-gemma-dda1882f352aValidation status: machine_predicted_unvalidated
Candidate categoriesMetaresearch
Consensus categoriesnone
DomainCandidate signal: none · Consensus signal: none
Study designCandidate signal: Observational · Consensus signal: Observational
GenreCandidate signal: Empirical · Consensus signal: none
Teacher disagreement score0.663
Threshold uncertainty score0.981

Codex and Gemma teacher scores by category

CategoryCodexGemma
Metaresearch0.0100.027
Meta-epidemiology (narrow)0.0000.000
Meta-epidemiology (broad)0.0010.000
Bibliometrics0.0000.001
Science and technology studies0.0000.000
Scholarly communication0.0000.000
Open science0.0000.000
Research integrity0.0000.000
Insufficient payload (model declined to judge)0.0000.000

Machine scores (provisional)

The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.

Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.

Opus teacher head0.083
GPT teacher head0.520
Teacher spread0.437 · how far apart the two teachers sit on this one work
Validation statusscore_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from it

Classification

machine, unvalidated

Machine predicted; a candidate call from one teacher head, not a consensus.

Study designObservational
Domainnot available
GenreEmpirical

How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".

Quick stats

Citations1
Published2025
Admission routes1
Has abstractyes

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