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Augmenting Healthcare Systems for Pandemic Preparedness: A Lean Six Sigma Perspective

2025· preprint· en· W4410770448 on OpenAlexaff
Utkarsh Chadha, Artem Kushnirenko, Darren Fernandes, Karishma Patel, Norah Jean Crothers, Harpreet Singh, Mete Isiksalan, Ibrahim Nasir, Stephen Armstrong, Kamran Behdinan

Bibliographic record

Venuenot available
Typepreprint
Languageen
FieldBusiness, Management and Accounting
TopicQuality and Supply Management
Canadian institutionsSickKids FoundationHospital for Sick ChildrenUniversity of Toronto
Fundersnot available
KeywordsPerspective (graphical)PandemicPreparednessSix SigmaHealth careBusinessCoronavirus disease 2019 (COVID-19)Lean Six SigmaHealthcare systemOperations managementProcess managementPolitical scienceLean manufacturingMedicineComputer scienceEngineeringManagementMarketingEconomicsArtificial intelligenceInternal medicine

Abstract

fetched live from OpenAlex

Background: Past global healthcare crises have vividly exposed major vulnerabilities in healthcare systems, including inefficiencies in hospital operations, delayed response times, and overburdened infrastructure. Traditional hospital systems that were built for routine care are sometimes not resilient or adaptable in the face of such crises, which resulted in global operational failures in healthcare systems. This study rigorously investigates how Lean Six Sigma (LSS) principles can be incorporated into conventional hospital operations to enhance the resilience of hospital infrastructures, streamline operations in time sensitive situations with precision in care, and improve waste reduction while being adaptable and sustainable, ensuring pandemic-preparedness. Methods: A comprehensive literature based-analysis was conducted using COVID-19 as a benchmark to evaluate hospital response strategies, failures, and influencing factors contributing to failure. This includes the critical assessment of ethical disruptions, operational weaknesses and healthcare business models. LSS principle applications, i.e., DMAIC, Value Stream Mapping, SIPOC, FMEA, and Control Charts were explored for facilitating efficient care, crisis response, and policy integration. Case studies from various regions were used to support the comparative analysis and emerging insights. Results: Findings show that adoption of LSS tools in the most vulnerable aspects of healthcare—like patient triage, supply chain optimization, and controlling and reducing mortality—can bring measurable improvements. Despite evidence of effectiveness, there are institutional barriers like capital constraints, resistance to change, data inconsistencies and vulnerabilities, and a lack of uniform legislative framework that impedes widespread LSS adoption. Most importantly, integrating data-driven LSS resulted in enhanced surge responsiveness and ethical compliance within the national healthcare frameworks and policies. Conclusion: LSS offers adaptable and scalable methodology to re-engineer conventional hospital operations and pandemic preparedness. The emphasis on ‘kaizen’ (continuous improvement), data-informed decision making, and focus on precision aligns with the needs of healthcare systems as revealed by recent crises. To unlock the potential for future preparedness, healthcare policies and systems must focus on institutionalizing LSS across public and private sectors through strategic investment, education, and cross-sector collaborations. This study provides a comprehensive framework for the policymakers, governments, epidemiologists, doctors, and hospital business managers for building resilient, efficient, and pandemic-ready hospitals.

Fetched live from OpenAlex and de-inverted. Abstracts are not stored in this database: the inverted indexes are 8.6 GB of the frame’s 9.3 GB of text, and the host has 13 GB free.

How this classification was reachedexpand

Full frame distilled prediction

Teacher imitation

Not calibrated prevalence, not ground truth. Human validation pending. Learned from the 10,348 direct Codex labels and 10,348 direct Gemma labels. Candidate is the union of thresholded teacher heads; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels or direct frontier model labels.

metaresearch head score (Codex)0.002
metaresearch head score (Gemma)0.000
Version: codex-gemma-dda1882f352aValidation status: machine_predicted_unvalidated
Candidate categoriesMeta-epidemiology (narrow), Scholarly communication
Consensus categoriesnone
DomainCandidate signal: none · Consensus signal: none
Study designCandidate signal: Theoretical or conceptual · Consensus signal: none
GenreCandidate signal: Empirical · Consensus signal: none
Teacher disagreement score0.906
Threshold uncertainty score1.000

Codex and Gemma teacher scores by category

CategoryCodexGemma
Metaresearch0.0020.000
Meta-epidemiology (narrow)0.0010.001
Meta-epidemiology (broad)0.0010.000
Bibliometrics0.0010.000
Science and technology studies0.0000.000
Scholarly communication0.0010.000
Open science0.0010.002
Research integrity0.0000.001
Insufficient payload (model declined to judge)0.0000.000

Machine scores (provisional)

The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.

Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.

Opus teacher head0.063
GPT teacher head0.324
Teacher spread0.261 · how far apart the two teachers sit on this one work
Validation statusscore_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from it

Classification

machine, unvalidated

Machine predicted; a candidate call from one teacher head, not a consensus.

Study designTheoretical or conceptual
Domainnot available
GenreEmpirical

How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".

Quick stats

Citations1
Published2025
Admission routes1
Has abstractyes

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