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Record W4410790145 · doi:10.1016/j.addbeh.2025.108392

Smoking cue reactivity and smoking motives in patients with early phase psychotic disorder

2025· article· en· W4410790145 on OpenAlexafffund
Marie‐Eve Couture, Sherry H. Stewart, Sean P. Barrett, Philip G. Tibbo, Heather Milliken, Maria Alexiadis, Nancy Robertson, Kimberley P. Good

Bibliographic record

VenueAddictive Behaviors · 2025
Typearticle
Languageen
FieldMedicine
TopicSmoking Behavior and Cessation
Canadian institutionsDalhousie UniversityNova Scotia Health Authority
FundersInstitute of Neurosciences, Mental Health and AddictionCanadian Institutes of Health ResearchDalhousie UniversityNova Scotia Health Research Foundation
KeywordsCue reactivityPsychologyReactivity (psychology)Clinical psychologyPsychosisPsychiatryMedicineCravingAddiction

Abstract

fetched live from OpenAlex

BACKGROUND: Rates of tobacco smoking in individuals with psychosis are high and are unfortunately accompanied by low rates of successful smoking cessation. Exposure to smoking-related cues is shown to reliably enhance cigarette cravings in dependent people who smoke recruited from the general population. Recent data suggests that smoking-related cues do not affect people who smoke diagnosed with established schizophrenia to the same degree as non-psychotic populations. However, less is known about how individuals in the early phase of psychotic illness react to these cues. In addition, it is unknown whether the smoking motives of individuals with early phase psychosis (EPP) differ from those of non-psychotic individuals who smoke (NPS). STUDY DESIGN: The present study compared cue-elicited cigarette cravings of EPP (n = 21, mean(sd) age27.6(7.8) years) to NPS (n = 40) in response to a smoking cue-reactivity paradigm and additionally, compared general self-reported motives for smoking across these groups. STUDY RESULTS: Similar to those with established psychosis, EPP individuals were less sensitive to the cue-reactivity paradigm, suggesting that individuals in early phase of illness may not be affected by tobacco cues to the same degree as NPS. Further, comparison of smoking motives suggests no differences between the reasons for smoking reported by individuals with EPP and NPS. CONCLUSIONS: These findings have implications for future studies aimed at identifying the source of the wide discrepancy in rates of tobacco smoking and smoking cessation across these two populations, and for the development of effective smoking cessation interventions for people who smoke with EPP.

Fetched live from OpenAlex and de-inverted. Abstracts are not stored in this database: the inverted indexes are 8.6 GB of the frame’s 9.3 GB of text, and the host has 13 GB free.

How this classification was reachedexpand

Full frame distilled prediction

Teacher imitation

Not calibrated prevalence, not ground truth. Human validation pending. Learned from the 10,348 direct Codex labels and 10,348 direct Gemma labels. Candidate is the union of thresholded teacher heads; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels or direct frontier model labels.

metaresearch head score (Codex)0.000
metaresearch head score (Gemma)0.000
Version: codex-gemma-dda1882f352aValidation status: machine_predicted_unvalidated
Candidate categoriesnone
Consensus categoriesnone
DomainCandidate signal: none · Consensus signal: none
Study designCandidate signal: Observational · Consensus signal: Observational
GenreCandidate signal: Empirical · Consensus signal: Empirical
Teacher disagreement score0.034
Threshold uncertainty score0.785

Codex and Gemma teacher scores by category

CategoryCodexGemma
Metaresearch0.0000.000
Meta-epidemiology (narrow)0.0000.000
Meta-epidemiology (broad)0.0000.000
Bibliometrics0.0000.001
Science and technology studies0.0000.000
Scholarly communication0.0000.000
Open science0.0000.000
Research integrity0.0000.000
Insufficient payload (model declined to judge)0.0000.000

Machine scores (provisional)

The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.

Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.

Opus teacher head0.010
GPT teacher head0.298
Teacher spread0.289 · how far apart the two teachers sit on this one work
Validation statusscore_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from it

Classification

machine, unvalidated

Machine predicted; a candidate call from one teacher head, not a consensus.

The models applied no category: nothing in the taxonomy fit this work.
Study designObservational
Domainnot available
GenreEmpirical

How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".

Quick stats

Citations0
Published2025
Admission routes2
Has abstractyes

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