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Record W4410805716 · doi:10.1016/j.kint.2025.02.021

Women and kidney health: conclusions from a Kidney Disease: Improving Global Outcomes (KDIGO) Controversies Conference

2025· article· en· W4410805716 on OpenAlexaff
Giorgina Barbara Piccoli, Sofia B. Ahmed, Fádi Fakhouri, Vesna D. Garovic, Michelle Hladunewich, Shilpanjali Jesudason, Jai Prakash, Angela C Webster, Elena Zakharova, Michael Cheung, Jennifer King, Michel Jadoul, Wolfgang C. Winkelmayer­, Christina Wyatt

Bibliographic record

VenueKidney International · 2025
Typearticle
Languageen
FieldMedicine
TopicPregnancy and preeclampsia studies
Canadian institutionsHealth Sciences CentreUniversity of TorontoSunnybrook Health Science CentreUniversity of Alberta
FundersBoehringer IngelheimAstraZeneca
KeywordsKidney diseaseMedicineKidneyIntensive care medicineDiseaseInternal medicine

Abstract

fetched live from OpenAlex

The KDIGO (Kidney Disease: Improving Global Outcomes) Controversies Conference on Women and Kidney Health was convened to identify key sex and gender issues in kidney care, practices for optimizing healthcare in women with kidney diseases, and priorities for future research. Participants emphasized the importance of addressing the influence of sex and gender in diagnosis, risk assessment, prognosis, and treatment of chronic kidney disease (CKD) and its complications, as well as considering issues across the lifespan (puberty, sexual and reproductive health, menopause). CKD is a risk factor for adverse pregnancy outcomes with every type of kidney disease and severity. All women of reproductive age known to have CKD should be counseled on contraception, the ideal timing of pregnancy, the risks and outcomes for mother and fetus, fertility treatments where these are available, medication management, and medical aspects of pregnancy termination. A successful pregnancy is possible across all severities of CKD, including in women living with dialysis or a kidney transplant. Pregnancy should be managed with a multidisciplinary care plan based upon the type of kidney disease and the presence and severity of kidney function impairment, hypertension, and proteinuria. Systematic assessment of blood pressure, proteinuria, and kidney function in all pregnancies would facilitate diagnosis of CKD and detection of acute kidney injury (AKI). Follow-up programs for women who experienced pregnancy-related AKI, preeclampsia, or other hypertensive disorders of pregnancy are important as these conditions may reflect undiagnosed CKD and have important implications for future cardiovascular health.

Fetched live from OpenAlex and de-inverted. Abstracts are not stored in this database: the inverted indexes are 8.6 GB of the frame’s 9.3 GB of text, and the host has 13 GB free.

How this classification was reachedexpand

Full frame machine prediction

Teacher imitation

Not calibrated prevalence, not ground truth. Human validation pending. The Gemma side is a direct model label for every work in the frame, read from the title-only record. The Codex side is a classifier learned from the 10,348 direct Codex labels and calibrated to design-weighted sample rates; fields without enough sample support carry no Codex call. Candidate is the union of the two sides; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels.

metaresearch head score (Codex)0.050
metaresearch head score (Gemma)0.066
Version: metacan-v3-hybrid-931329e0061cValidation status: machine_predicted_unvalidated
Candidate categoriesnone
Consensus categoriesnone
DomainCandidate signal: none · Consensus signal: none
Study designCandidate signal: Not applicable · Consensus signal: Not applicable
GenreCandidate signal: Empirical · Consensus signal: none
Teacher disagreement score0.050
Threshold uncertainty score0.265

Distilled classifier scores by category (both heads)

CategoryCodexGemma
Metaresearch0.0500.066
Meta-epidemiology (narrow)0.0020.001
Meta-epidemiology (broad)0.0030.004
Bibliometrics0.0030.005
Science and technology studies0.0030.003
Scholarly communication0.0080.005
Open science0.0030.007
Research integrity0.0120.013
Insufficient payload (model declined to judge)0.0090.001

Machine scores (provisional)

The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.

Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.

Opus teacher head0.016
GPT teacher head0.302
Teacher spread0.286 · how far apart the two teachers sit on this one work
Validation statusscore_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from it

Classification

machine, unvalidated

Machine predicted; a candidate call from one source (direct Gemma or distilled Codex), not a consensus.

The models applied no category: nothing in the taxonomy fit this work.
Study designNot applicable
Domainnot available
GenreEmpirical

How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".

Quick stats

Citations17
Published2025
Admission routes1
Has abstractno

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