Laser‐Patterned Diamond Electrodes for Adhesion and Proliferation of Human Mesenchymal Stem Cells
Why this work is in the frame
A frame that forgets how it found something cannot be audited. These are the routes that admitted this work.
Bibliographic record
Abstract
The ability to form diamond electrodes on insulating polycrystalline diamond substrates using single‐step laser patterning and the use of these electrodes as a substrate that supports the adhesion and proliferation of human mesenchymal stem cells (hMSCs) are demonstrated. Laser‐induced graphitization results in a conductive amorphous carbon surface, rich in oxygen‐ and nitrogen‐terminated groups. This leads to an electrode with a high specific capacitance of 182 μF cm 2 , a wide water window of 3.25 V, and a low electrochemical impedance of 129 Ω cm 2 at 1 kHz—essential attributes for effective bioelectronic cell interfaces. The electrode's surface exhibits no cytotoxic responses with hMSCs, supporting cell adhesion and proliferation. Cells cultured on the electrode display significant elongation and alignment along the direction of the laser‐patterned microgrooves—an additional modality for cellular modulation. The combination of favorable electrochemical performance and effective cellular control makes laser‐patterned diamond electrodes a versatile platform in stem cell therapeutics. This direct fabrication approach paves the way for the integration of diamond electrodes in bioelectronic devices, offering new opportunities for tissue engineering and electroactive biomaterial applications.
Fetched live from OpenAlex and de-inverted. Abstracts are not stored in this database: the inverted indexes are 8.6 GB of the frame’s 9.3 GB of text, and the host has 13 GB free.
Full frame distilled prediction
Teacher imitationNot calibrated prevalence, not ground truth. Human validation pending. Learned from the 10,348 direct Codex labels and 10,348 direct Gemma labels. Candidate is the union of thresholded teacher heads; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels or direct frontier model labels.
Codex and Gemma teacher scores by category
| Category | Codex | Gemma |
|---|---|---|
| Metaresearch | 0.000 | 0.000 |
| Meta-epidemiology (narrow) | 0.000 | 0.000 |
| Meta-epidemiology (broad) | 0.000 | 0.000 |
| Bibliometrics | 0.001 | 0.001 |
| Science and technology studies | 0.000 | 0.000 |
| Scholarly communication | 0.000 | 0.000 |
| Open science | 0.000 | 0.000 |
| Research integrity | 0.000 | 0.000 |
| Insufficient payload (model declined to judge) | 0.000 | 0.000 |
Machine scores (provisional)
The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.
Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.
score_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from it