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Record W4410839855 · doi:10.1093/jcag/gwaf009

Evaluating the process of care for persons admitted to Toronto area hospitals with acute severe ulcerative colitis

2025· article· en· W4410839855 on OpenAlexafffundabout
Nasruddin Sabrie, Sonya Vukovic, Xin You, Surain B. Roberts, Fahad Razak, Amol A. Verma, Laura E. Targownik

Bibliographic record

VenueJournal of the Canadian Association of Gastroenterology · 2025
Typearticle
Languageen
FieldBiochemistry, Genetics and Molecular Biology
TopicInflammatory Bowel Disease
Canadian institutionsMount Sinai HospitalSt. Michael's HospitalUniversity of Toronto
FundersNatural Sciences and Engineering Research Council of CanadaCanadian Institutes of Health ResearchAlliance de recherche numérique du CanadaCanadian Frailty NetworkUniversity of Toronto
KeywordsMedicineUlcerative colitisSpecialtyColectomyOdds ratioLogistic regressionInternal medicineRetrospective cohort studyInflammatory bowel diseaseEmergency medicineDiseaseFamily medicine

Abstract

fetched live from OpenAlex

Background: Acute severe ulcerative colitis (ASUC) is associated with significant morbidity. In patients with ulcerative colitis (UC), the estimated lifetime risk of developing severe colitis is 25%. Several gastrointestinal societies have provided recommendations on pathways of care for managing ASUC. The degree to which they are adhered to in different care settings remains unclear. Methods: We conducted a retrospective review using data from 7 acute-care hospitals collected through the general medicine inpatient initiative (GEMINI), a hospital research collaborative that collects administrative and clinical data from hospital information systems. We identified all patients with the most responsible inpatient discharge diagnosis of ulcerative colitis between April 2015 and December 2019. The primary outcome was the difference in hospital length of stay of patients admitted with ASUC based on hospital-type; community, academic, or inflammatory bowel disease (IBD)-focussed sites. Results: = .094). Adverse events were uncommon overall. In our multiple logistic regression analysis, we identified that admission to an IBD-focussed centre compared to an academic centre, carried an odds ratio of 2.07 (95% CI, 1.16-3.78) for the outcome of inpatient-colectomy. Conclusions: The processes of care for patients with ASUC varied on the basis of the type of hospital they were admitted to, with the IBD specialty centre providing the most guideline adherent care. Low-cost interventions should be utilized to promote adherence to clinical practice recommendations.

Fetched live from OpenAlex and de-inverted. Abstracts are not stored in this database: the inverted indexes are 8.6 GB of the frame’s 9.3 GB of text, and the host has 13 GB free.

How this classification was reachedexpand

Full frame machine prediction

Teacher imitation

Not calibrated prevalence, not ground truth. Human validation pending. The Gemma side is a direct model label for every work in the frame, read from the title-only record. The Codex side is a classifier learned from the 10,348 direct Codex labels and calibrated to design-weighted sample rates; fields without enough sample support carry no Codex call. Candidate is the union of the two sides; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels.

metaresearch head score (Codex)0.004
metaresearch head score (Gemma)0.022
Version: metacan-v3-hybrid-931329e0061cValidation status: machine_predicted_unvalidated
Candidate categoriesnone
Consensus categoriesnone
DomainCandidate signal: none · Consensus signal: none
Study designCandidate signal: Observational · Consensus signal: Observational
GenreCandidate signal: Empirical · Consensus signal: Empirical
Teacher disagreement score0.779
Threshold uncertainty score0.440

Distilled classifier scores by category (both heads)

CategoryCodexGemma
Metaresearch0.0040.022
Meta-epidemiology (narrow)0.0000.000
Meta-epidemiology (broad)0.0000.001
Bibliometrics0.0020.003
Science and technology studies0.0010.001
Scholarly communication0.0020.001
Open science0.0010.001
Research integrity0.0000.001
Insufficient payload (model declined to judge)0.0010.000

Machine scores (provisional)

The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.

Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.

Opus teacher head0.006
GPT teacher head0.272
Teacher spread0.266 · how far apart the two teachers sit on this one work
Validation statusscore_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from it

Classification

machine, unvalidated

Machine predicted; a candidate call from one source (direct Gemma or distilled Codex), not a consensus.

The models applied no category: nothing in the taxonomy fit this work.
Study designObservational
Domainnot available
GenreEmpirical

How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".

Quick stats

Citations0
Published2025
Admission routes3
Has abstractyes

Explore more

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