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Record W4410859733 · doi:10.1080/00224499.2025.2503896

Sexual Activity, Pleasure, and Testosterone: A Biopsychosocial Analysis of Women Living With and Without HIV in British Columbia, Canada

2025· article· en· W4410859733 on OpenAlexafffundabout
Katherine D. Mathews, Shayda A. Swann, Alasdair Campbell, Monica Lee, Shelly Tognazzini, Allison Carter, Mona Loutfy, Elizabeth M. King, Valerie Nicholson, Angela Kaida, Hélène C. F. Côté, Melanie C. M. Murray

Bibliographic record

VenueThe Journal of Sex Research · 2025
Typearticle
Languageen
FieldMedicine
TopicHIV/AIDS Research and Interventions
Canadian institutionsWomen's College HospitalWomen's Health Research InstituteUniversity of TorontoB.C. Women's Hospital & Health CentreSimon Fraser UniversityUniversity of British Columbia
FundersCanadian Institutes of Health ResearchSimon Fraser UniversityCanadian HIV Trials Network, Canadian Institutes of Health ResearchMichael Smith Health Research BC
KeywordsBiopsychosocial modelHuman immunodeficiency virus (HIV)Testosterone (patch)PleasurePsychologyMedicineGender studiesGerontologyClinical psychologySociologyPsychotherapistFamily medicineInternal medicine

Abstract

fetched live from OpenAlex

Sexual health research comparing women with and without human immunodeficiency virus (HIV) often pathologizes women living with HIV, overlooking biopsychosocial factors that may drive differences between groups. Low testosterone levels have been reported among women living with HIV; however, how this may impact sexual health outcomes remains unclear. We compared the prevalence of sexual activity and sexual pleasure between women with and without HIV in British Columbia and examined associations with psychosocial variables and testosterone. There were no significant differences in the prevalence of partnered sexual activity (45.7% vs. 52.8%) or sexual pleasure (64.1% vs. 70.4%) between women with and without HIV, respectively. Women with HIV reported less masturbation (43.2%) compared to women without HIV (64.6%). In multivariable logistic regression models, both HIV and testosterone were independently associated with masturbation, but not with partnered sexual activity or sexual pleasure. Several psychosocial factors were associated with sexual outcomes including age, relationship status, income, substance use, physical health, and children. In HIV-stratified analyses, knowledge of Undetectable=Untransmittable (U=U), having an undetectable HIV-RNA viral load and a CD4 count > 500 cells/μl showed significant associations. This work highlights positive aspects of sexuality and the confluence of social norms, internalized perceptions, and biology in shaping women's sexual well-being.

Fetched live from OpenAlex and de-inverted. Abstracts are not stored in this database: the inverted indexes are 8.6 GB of the frame’s 9.3 GB of text, and the host has 13 GB free.

How this classification was reachedexpand

Full frame distilled prediction

Teacher imitation

Not calibrated prevalence, not ground truth. Human validation pending. Learned from the 10,348 direct Codex labels and 10,348 direct Gemma labels. Candidate is the union of thresholded teacher heads; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels or direct frontier model labels.

metaresearch head score (Codex)0.004
metaresearch head score (Gemma)0.001
Version: codex-gemma-dda1882f352aValidation status: machine_predicted_unvalidated
Candidate categoriesnone
Consensus categoriesnone
DomainCandidate signal: none · Consensus signal: none
Study designCandidate signal: Observational · Consensus signal: Observational
GenreCandidate signal: Empirical · Consensus signal: Empirical
Teacher disagreement score0.280
Threshold uncertainty score0.321

Codex and Gemma teacher scores by category

CategoryCodexGemma
Metaresearch0.0040.001
Meta-epidemiology (narrow)0.0000.000
Meta-epidemiology (broad)0.0000.000
Bibliometrics0.0000.001
Science and technology studies0.0000.000
Scholarly communication0.0000.000
Open science0.0000.000
Research integrity0.0000.001
Insufficient payload (model declined to judge)0.0000.000

Machine scores (provisional)

The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.

Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.

Opus teacher head0.028
GPT teacher head0.354
Teacher spread0.326 · how far apart the two teachers sit on this one work
Validation statusscore_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from it

Classification

machine, unvalidated

Machine predicted; a candidate call from one teacher head, not a consensus.

The models applied no category: nothing in the taxonomy fit this work.
Study designObservational
Domainnot available
GenreEmpirical

How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".

Quick stats

Citations2
Published2025
Admission routes3
Has abstractyes

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