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Record W4410871823 · doi:10.1007/s42000-025-00678-8

Interrelationship between the menstrual cycle and the phenomena associated with orthodontic tooth movement in young female patients: a systematic review

2025· review· en· W4410871823 on OpenAlexaboutno aff
Hayat M R M A Almansour, Athanasios E. Athanasiou, Miltiadis A. Makrygiannakis, Eleftherios G. Kaklamanos

Bibliographic record

VenueHORMONES · 2025
Typereview
Languageen
FieldDentistry
TopicOrthodontics and Dentofacial Orthopedics
Canadian institutionsnot available
Fundersnot available
KeywordsMenstrual cycleMenstruationMedicineLuteal phaseCochrane LibraryDentistryRandomized controlled trialFollicular phaseHormoneEndocrinologySurgeryInternal medicine

Abstract

fetched live from OpenAlex

PURPOSE: Alterations in the levels of female sex hormones throughout the menstrual cycle can affect bone turnover, which, in turn, may influence the phenomena related to orthodontic tooth movement. The aim of the present study was to investigate in a systematic manner and summarize the existing evidence regarding the interrelationship between the menstrual cycle and the phenomena associated with orthodontic treatment in young females. METHOD: An unrestricted search was performed. Studies investigating the interdependence between the menstrual cycle in young females and the phenomena associated with tooth movement were reviewed. Study retrieval and selection were followed by extraction of relevant data and risk of bias assessment with the Cochrane ROB 2 tool for randomized controlled studies and the Newcastle-Ottawa Scale for the remaining studies. RESULTS: Finally, seven studies, with variable risk of bias, met the inclusion criteria. Overall, force application during menstruation led to greater tooth movement. Orthodontic pain increased when forces were applied in the luteal phase and was exacerbated when patients presented with primary dysmenorrhea. Orthodontic treatment did not affect the duration of menstrual bleeding or cycle length in the long term. CONCLUSION: The menstrual cycle may exert an effect on the phenomena associated with orthodontic tooth movement: an orthodontist should therefore be able to identify possible repercussions.

Fetched live from OpenAlex and de-inverted. Abstracts are not stored in this database: the inverted indexes are 8.6 GB of the frame’s 9.3 GB of text, and the host has 13 GB free.

How this classification was reachedexpand

Full frame distilled prediction

Teacher imitation

Not calibrated prevalence, not ground truth. Human validation pending. Learned from the 10,348 direct Codex labels and 10,348 direct Gemma labels. Candidate is the union of thresholded teacher heads; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels or direct frontier model labels.

metaresearch head score (Codex)0.003
metaresearch head score (Gemma)0.002
Version: codex-gemma-dda1882f352aValidation status: machine_predicted_unvalidated
Candidate categoriesMeta-epidemiology (narrow)
Consensus categoriesnone
DomainCandidate signal: none · Consensus signal: none
Study designCandidate signal: Systematic review · Consensus signal: Systematic review
GenreCandidate signal: Review · Consensus signal: Review
Teacher disagreement score0.092
Threshold uncertainty score1.000

Codex and Gemma teacher scores by category

CategoryCodexGemma
Metaresearch0.0030.002
Meta-epidemiology (narrow)0.0010.000
Meta-epidemiology (broad)0.0030.000
Bibliometrics0.0000.001
Science and technology studies0.0000.000
Scholarly communication0.0000.000
Open science0.0000.000
Research integrity0.0000.001
Insufficient payload (model declined to judge)0.0000.000

Machine scores (provisional)

The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.

Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.

Opus teacher head0.029
GPT teacher head0.301
Teacher spread0.272 · how far apart the two teachers sit on this one work
Validation statusscore_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from it

Classification

machine, unvalidated

Machine predicted; a candidate call from one teacher head, not a consensus.

Study designSystematic review
Domainnot available
GenreReview

How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".

Quick stats

Citations2
Published2025
Admission routes1
Has abstractyes

Explore more

Same venueHORMONESSame topicOrthodontics and Dentofacial OrthopedicsFrench-language works237,207