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Record W4410873883 · doi:10.1111/dar.14086

Patterns of Acute Gamma‐Hydroxybutyrate Harms Requiring Ambulance Attendance: Should Greater Focus Be on Regional Areas?

2025· article· en· W4410873883 on OpenAlexaboutno aff
Naomi Beard, J. C. Wilson, Bosco Rowland, Ziad Nehme, Dan I. Lubman, Rowan P. Ogeil

Bibliographic record

VenueDrug and Alcohol Review · 2025
Typearticle
Languageen
FieldPharmacology, Toxicology and Pharmaceutics
TopicForensic Toxicology and Drug Analysis
Canadian institutionsnot available
FundersAustralian Institute of Health and Welfare, Australian GovernmentMonash UniversityDepartment of Health, State Government of VictoriaDepartment of Health and Human Services, State Government of Victoria
KeywordsMedicineQuarter (Canadian coin)DemographyAttendancePopulationMedical emergencyMetropolitan areaEmergency medicineGeographyEnvironmental health

Abstract

fetched live from OpenAlex

INTRODUCTION: Gamma-hydroxybutyrate (GHB) use and attributable harms have been increasing in Europe and Australia. However, there are limited population surveillance tools available to map and track acute GHB-related harms, particularly outside metropolitan areas. The present study examined GHB-related ambulance attendances from January 2015 to March 2024 across the state of Victoria, and in Greater Geelong, the region associated with the highest number of attendances outside the state capital. METHODS: Retrospective analysis of all GHB-related ambulance attendances between 1 January 2015 and 31 March 2024 from the Victorian arm of the National Ambulance Surveillance System. Descriptives and time series analyses were used to present demographic and spatio-temporal patterns. RESULTS: There were 16,971 ambulance attendances for GHB during the study period. A sinusoidal trend was apparent in the statewide data, suggesting a seasonal factor to GHB-related attendances, with greater numbers occurring during quarter four of each year. Whilst a seasonal effect was also apparent in Greater Geelong, increases in attendances have been consistent since quarter four of 2021 (between 7% and 34%). The magnitude of these increases was not observed in other regional areas. DISCUSSION AND CONCLUSIONS: Acute GHB-related harms have increased in Victoria over time, in addition to a seasonal effect being apparent that coincided with summer in the Southern Hemisphere. Our findings support recent media reports from emergency department workers in the region of Greater Geelong that GHB harms have risen. This study demonstrates the value of using ambulance surveillance data to assess pre-hospital harms resulting from GHB use.

Fetched live from OpenAlex and de-inverted. Abstracts are not stored in this database: the inverted indexes are 8.6 GB of the frame’s 9.3 GB of text, and the host has 13 GB free.

How this classification was reachedexpand

Full frame distilled prediction

Teacher imitation

Not calibrated prevalence, not ground truth. Human validation pending. Learned from the 10,348 direct Codex labels and 10,348 direct Gemma labels. Candidate is the union of thresholded teacher heads; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels or direct frontier model labels.

metaresearch head score (Codex)0.001
metaresearch head score (Gemma)0.000
Version: codex-gemma-dda1882f352aValidation status: machine_predicted_unvalidated
Candidate categoriesMeta-epidemiology (narrow)
Consensus categoriesnone
DomainCandidate signal: none · Consensus signal: none
Study designCandidate signal: Not applicable · Consensus signal: none
GenreCandidate signal: Empirical · Consensus signal: Empirical
Teacher disagreement score0.483
Threshold uncertainty score1.000

Codex and Gemma teacher scores by category

CategoryCodexGemma
Metaresearch0.0010.000
Meta-epidemiology (narrow)0.0000.000
Meta-epidemiology (broad)0.0010.000
Bibliometrics0.0000.000
Science and technology studies0.0000.000
Scholarly communication0.0000.000
Open science0.0000.000
Research integrity0.0000.001
Insufficient payload (model declined to judge)0.0010.000

Machine scores (provisional)

The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.

Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.

Opus teacher head0.128
GPT teacher head0.439
Teacher spread0.312 · how far apart the two teachers sit on this one work
Validation statusscore_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from it

Classification

machine, unvalidated

Machine predicted; a candidate call from one teacher head, not a consensus.

Study designNot applicable
Domainnot available
GenreEmpirical

How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".

Quick stats

Citations0
Published2025
Admission routes1
Has abstractyes

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