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Record W4410885215 · doi:10.1007/s00125-025-06370-1

European Association for the Study of Diabetes (EASD) Standard Operating Procedure for the development of guidelines

2025· article· en· W4410885215 on OpenAlexafffund
Thomas Karagiannis, Andrew Advani, Melanie J. Davies, Stefano Del Prato, Seán F. Dinneen, Oliver Kuß, Valentina Lorenzoni, Chantal Mathieu, Dı́dac Mauricio, Tsvetalina Tankova, Francesco Zaccardi, Richard I. G. Holt, Απόστολος Τσάπας

Bibliographic record

VenueDiabetologia · 2025
Typearticle
Languageen
FieldMedicine
TopicClinical practice guidelines implementation
Canadian institutionsSt. Michael's Hospital
FundersUniversità degli Studi di FirenzeMcMaster University
KeywordsHuman physiologyDiabetes mellitusMedicineAssociation (psychology)Internal medicineEndocrinologyPsychology

Abstract

fetched live from OpenAlex

The European Association for the Study of Diabetes (EASD) has developed a Standard Operating Procedure (SOP) for the development of clinical practice guidelines, ensuring adherence to rigorous methodological standards based on the principles of the Grading of Recommendations, Assessment, Development, and Evaluation (GRADE) framework. Key components include a transparent process for managing conflicts of interest, the incorporation of multidisciplinary panels including individuals with lived experience of diabetes, an evidence synthesis based on comprehensive systematic reviews, and an explicit peer review process. This SOP delineates the roles and responsibilities of the main structures involved, including the Guidelines Oversight Committee, Guideline Development Panels, and Evidence Synthesis Teams. Additionally, the SOP describes the main stages in guideline development, namely scoping of the guideline topic, evidence synthesis, development of Evidence-to-Decision frameworks for the formulation of clear, patient-centred recommendations, writing of the guideline document and the review process.

Fetched live from OpenAlex and de-inverted. Abstracts are not stored in this database: the inverted indexes are 8.6 GB of the frame’s 9.3 GB of text, and the host has 13 GB free.

How this classification was reachedexpand

Full frame machine prediction

Teacher imitation

Not calibrated prevalence, not ground truth. Human validation pending. The Gemma side is a direct model label for every work in the frame, read from the title-only record. The Codex side is a classifier learned from the 10,348 direct Codex labels and calibrated to design-weighted sample rates; fields without enough sample support carry no Codex call. Candidate is the union of the two sides; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels.

metaresearch head score (Codex)0.189
metaresearch head score (Gemma)0.379
Version: metacan-v3-hybrid-931329e0061cValidation status: machine_predicted_unvalidated
Candidate categoriesMetaresearch
Consensus categoriesMetaresearch
DomainCandidate signal: Methods · Consensus signal: none
Study designCandidate signal: Not applicable · Consensus signal: Not applicable
GenreCandidate signal: Protocol · Consensus signal: none
Teacher disagreement score0.811
Threshold uncertainty score1.000

Distilled classifier scores by category (both heads)

CategoryCodexGemma
Metaresearch0.1890.379
Meta-epidemiology (narrow)0.0020.003
Meta-epidemiology (broad)0.0040.005
Bibliometrics0.0150.017
Science and technology studies0.0020.005
Scholarly communication0.0120.004
Open science0.0040.007
Research integrity0.0080.013
Insufficient payload (model declined to judge)0.0410.036

Machine scores (provisional)

The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.

Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.

Opus teacher head0.207
GPT teacher head0.485
Teacher spread0.278 · how far apart the two teachers sit on this one work
Validation statusscore_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from it

Classification

machine, unvalidated

Machine predicted; the direct Gemma label and the distilled Codex classifier agree on what is shown here.

Study designNot applicable
DomainMethods
GenreProtocol

How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".

Quick stats

Citations9
Published2025
Admission routes2
Has abstractyes

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