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Record W4410887978 · doi:10.1371/journal.pone.0323246

Antimicrobial-resistance of Escherichia coli in dogs and cats: A scoping review

2025· review· en· W4410887978 on OpenAlexaff
Rasaq A. Ojasanya, J. Scott Weese, Zvonimir Poljak, Kurtis E. Sobkowich, Uththami Kukathasan, Theresa M. Bernardo

Bibliographic record

VenuePLoS ONE · 2025
Typereview
Languageen
FieldBiochemistry, Genetics and Molecular Biology
TopicAntibiotic Resistance in Bacteria
Canadian institutionsUniversity of Guelph
FundersIDEXX Laboratories
KeywordsAntimicrobialAntimicrobial stewardshipAntibiotic resistanceMEDLINEMedicineObservational studyDrug resistanceCATSCompanion animalVeterinary medicineBiologyInternal medicineMicrobiologyAntibiotics

Abstract

fetched live from OpenAlex

Pathogenic Escherichia coli causes a range of clinical manifestations in dogs and cats, and the use of antimicrobials in pets is associated with the risk of antimicrobial resistance (AMR). Pets contribute to the dissemination of AMR both within their species and to humans. This study conducts a scoping review to assess the existing evidence on the AMR of E. coli in dogs and cats, noting the purpose of antimicrobial susceptibility testing (AST) and determining the knowledge gaps to inform future research. The search utilized specific and generic strings aligned with the research objectives, spanning databases such as MEDLINE®, Web of Science, Biological Science Collection, AGRICOLA, CAB Direct, and Google Scholar, from January 1990 to July 2023. The study selection included only articles published in English and related to primary research. Following deduplication, the initial search identified 1,205 studies. After a detailed full-text review, 108 independent studies were identified. Studies on the AMR of E. coli in companion animals are largely concentrated in North America and Western Europe. Most of the studies were observational and were conducted in veterinary clinics. AST was primarily conducted to guide the antimicrobial treatment of E. coli infections in pets. Although not all studies provided clinical histories, among those that did, multi-drug resistant (MDR) E. coli was reported in both healthy and ailing pets. The detection of MDR E. coli in healthy and sick pets serve as a clarion call for antimicrobial stewardship. However, the limited number of studies dedicated to AMR monitoring and surveillance programs for companion animals raises a substantial concern.

Fetched live from OpenAlex and de-inverted. Abstracts are not stored in this database: the inverted indexes are 8.6 GB of the frame’s 9.3 GB of text, and the host has 13 GB free.

How this classification was reachedexpand

Full frame machine prediction

Teacher imitation

Not calibrated prevalence, not ground truth. Human validation pending. The Gemma side is a direct model label for every work in the frame, read from the title-only record. The Codex side is a classifier learned from the 10,348 direct Codex labels and calibrated to design-weighted sample rates; fields without enough sample support carry no Codex call. Candidate is the union of the two sides; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels.

metaresearch head score (Codex)0.005
metaresearch head score (Gemma)0.026
Version: metacan-v3-hybrid-931329e0061cValidation status: machine_predicted_unvalidated
Candidate categoriesnone
Consensus categoriesnone
DomainCandidate signal: none · Consensus signal: none
Study designCandidate signal: Systematic review · Consensus signal: Systematic review
GenreCandidate signal: Review · Consensus signal: Review
Teacher disagreement score0.019
Threshold uncertainty score0.029

Distilled classifier scores by category (both heads)

CategoryCodexGemma
Metaresearch0.0050.026
Meta-epidemiology (narrow)0.0010.001
Meta-epidemiology (broad)0.0040.004
Bibliometrics0.0190.016
Science and technology studies0.0010.001
Scholarly communication0.0030.003
Open science0.0010.002
Research integrity0.0030.001
Insufficient payload (model declined to judge)0.0040.000

Machine scores (provisional)

The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.

Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.

Opus teacher head0.033
GPT teacher head0.300
Teacher spread0.266 · how far apart the two teachers sit on this one work
Validation statusscore_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from it

Classification

machine, unvalidated

Machine predicted; a candidate call from one source (direct Gemma or distilled Codex), not a consensus.

The models applied no category: nothing in the taxonomy fit this work.
Study designSystematic review
Domainnot available
GenreReview

How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".

Quick stats

Citations2
Published2025
Admission routes1
Has abstractyes

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