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Record W4410903571 · doi:10.62347/crqk7620

Local injection of platelet-rich plasma is effective for non-healing hand wounds

2025· article· en· W4410903571 on OpenAlexaboutno aff
Jiangqiang Chen

Bibliographic record

VenueAmerican Journal of Translational Research · 2025
Typearticle
Languageen
FieldMedicine
TopicPeriodontal Regeneration and Treatments
Canadian institutionsnot available
Fundersnot available
KeywordsPlatelet-rich plasmaWound healingPlateletMedicineSurgeryInternal medicine

Abstract

fetched live from OpenAlex

OBJECTIVE: To evaluate the clinical efficacy of local platelet-rich plasma (PRP) injections in treating non-healing hand wounds. METHODS: Data of 80 patients with non-healing hand wounds were retrospectively selected for this study. Among them, 48 patients in the research group received local PRP injections, while 32 patients in the control group were treated with conventional dressing changes. The outcomes assessed included treatment efficacy, safety, frequency of dressing change, wound healing time, duration of hospitalization, treatment costs, wound healing rate, wound infection rate, Vancouver Scar Scale (VSS) scores, Bates-Jensen Wound Assessment Tool (BWAT) scores, Visual Analogue Scale (VAS) scores, serum wound growth factors, and patient satisfaction with wound appearance. RESULTS: The research group demonstrated significantly superior outcomes compared to the control group, including higher overall treatment efficacy and wound healing rates. Furthermore, the research group exhibited a significantly lower incidence of adverse events, reduced frequency of dressing changes, shorter wound healing time, reduced hospitalization duration, lower treatment costs, and a lower infection rate. Post-treatment assessments revealed significantly lower VSS, BWAT, and VAS scores in the research group. Additionally, the upregulation of serum wound growth factors was more pronounced in the research group following treatment. CONCLUSIONS: Local PRP injection demonstrates clear efficacy in the management of non-healing hand wounds.

Fetched live from OpenAlex and de-inverted. Abstracts are not stored in this database: the inverted indexes are 8.6 GB of the frame’s 9.3 GB of text, and the host has 13 GB free.

How this classification was reachedexpand

Full frame machine prediction

Teacher imitation

Not calibrated prevalence, not ground truth. Human validation pending. The Gemma side is a direct model label for every work in the frame, read from the title-only record. The Codex side is a classifier learned from the 10,348 direct Codex labels and calibrated to design-weighted sample rates; fields without enough sample support carry no Codex call. Candidate is the union of the two sides; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels.

metaresearch head score (Codex)0.001
metaresearch head score (Gemma)0.002
Version: metacan-v3-hybrid-931329e0061cValidation status: machine_predicted_unvalidated
Candidate categoriesnone
Consensus categoriesnone
DomainCandidate signal: none · Consensus signal: none
Study designCandidate signal: Observational · Consensus signal: none
GenreCandidate signal: Empirical · Consensus signal: Empirical
Teacher disagreement score0.002
Threshold uncertainty score0.006

Distilled classifier scores by category (both heads)

CategoryCodexGemma
Metaresearch0.0010.002
Meta-epidemiology (narrow)0.0000.000
Meta-epidemiology (broad)0.0010.000
Bibliometrics0.0000.000
Science and technology studies0.0000.000
Scholarly communication0.0000.000
Open science0.0000.000
Research integrity0.0000.000
Insufficient payload (model declined to judge)0.0020.000

Machine scores (provisional)

The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.

Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.

Opus teacher head0.034
GPT teacher head0.405
Teacher spread0.372 · how far apart the two teachers sit on this one work
Validation statusscore_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from it

Classification

machine, unvalidated

Machine predicted; a candidate call from one source (direct Gemma or distilled Codex), not a consensus.

The models applied no category: nothing in the taxonomy fit this work.
Study designObservational
Domainnot available
GenreEmpirical

How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".

Quick stats

Citations0
Published2025
Admission routes1
Has abstractyes

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Same venueAmerican Journal of Translational ResearchSame topicPeriodontal Regeneration and TreatmentsFrench-language works237,207